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Published in: Pediatric Cardiology 1/2012

01-01-2012 | Original Article

John Locke, “Rhickets” and the Cardiopulmonary Circulation

Author: A. N. Williams

Published in: Pediatric Cardiology | Issue 1/2012

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Excerpt

In 2009, Pediatric Cardiology published a short article describing a postmortem examination performed June 1666 by physician/philosopher John Locke (1632–1704) on an 18-month-old child who was “dead of the Rhickets.” Although Locke attributed the death to rickets, his clear descriptions of the clinical history and postmortem findings are more consistent with a congenital cardiac malformation and Ebstein’s anomaly in addition to the rickets [50]. This short article places this case in its historical context, a period during which the Galenic view of the cardiopulmonary circulation was overturned. …
Literature
1.
go back to reference Anstey P, Principe L (eds) John Locke: writings on natural philosophy and medicine. Oxford (forthcoming) Anstey P, Principe L (eds) John Locke: writings on natural philosophy and medicine. Oxford (forthcoming)
2.
go back to reference Ansty P, Burrows J, John Locke, Thomas Sydenham, and the authorship of two medical essays. e BLJ 2009 Article 3 Ansty P, Burrows J, John Locke, Thomas Sydenham, and the authorship of two medical essays. e BLJ 2009 Article 3
3.
go back to reference Aubrey J (1987) Brief lives: William Harvey. Penguin Books, London, pp 212–213 Aubrey J (1987) Brief lives: William Harvey. Penguin Books, London, pp 212–213
4.
go back to reference Bacon F (1960) Instauratio Magnae: the great instauration (1620). Indianapolis, p 7 Bacon F (1960) Instauratio Magnae: the great instauration (1620). Indianapolis, p 7
6.
go back to reference Bylebyl JJ (1979) The medical side of Harvey’s discovery. In: Bylebyl JJ (ed) William Harvey and his age. Johns Hopkins, Baltimore, pp 28–102 Bylebyl JJ (1979) The medical side of Harvey’s discovery. In: Bylebyl JJ (ed) William Harvey and his age. Johns Hopkins, Baltimore, pp 28–102
7.
go back to reference Coleman WO (2000) The significance of John Locke’s medical studies for his economic thought. Hist Polit Econ 32:711–731CrossRef Coleman WO (2000) The significance of John Locke’s medical studies for his economic thought. Hist Polit Econ 32:711–731CrossRef
8.
go back to reference Conrad LI, Neve M, Nutton V, Porter R, Wear A (1995) The Western medical tradition. Cambridge University Press, Cambridge, p 346 Conrad LI, Neve M, Nutton V, Porter R, Wear A (1995) The Western medical tradition. Cambridge University Press, Cambridge, p 346
9.
go back to reference Conrad LI, Neve M, Nutton V, Porter R, Wear A (1995) The Western medical tradition. Cambridge University Press, Cambridge, pp 339–340 Conrad LI, Neve M, Nutton V, Porter R, Wear A (1995) The Western medical tradition. Cambridge University Press, Cambridge, pp 339–340
10.
go back to reference Conrad LI, Neve M, Nutton V, Porter R, Wear A (1995) The Western medical tradition. Cambridge University Press, Cambridge, p 344 Conrad LI, Neve M, Nutton V, Porter R, Wear A (1995) The Western medical tradition. Cambridge University Press, Cambridge, p 344
11.
go back to reference Davies JH, Shaw NJ (2011) Preventable but no strategy: vitamin D deficiency in the UK. Arch Dis Child 96:614–615PubMedCrossRef Davies JH, Shaw NJ (2011) Preventable but no strategy: vitamin D deficiency in the UK. Arch Dis Child 96:614–615PubMedCrossRef
12.
go back to reference Locke to John Locke Senior 20 December 1660 The Correspondence of John Locke. edited by de Beer, Clarendon Press, Oxford: 1989: Vol 1 p 162 Locke to John Locke Senior 20 December 1660 The Correspondence of John Locke. edited by de Beer, Clarendon Press, Oxford: 1989: Vol 1 p 162
13.
go back to reference Dewhurst K (1963) John Locke (1632–1704), physician and philosopher: a medical biography. Wellcome Historical Medical Library, London, p 6 Dewhurst K (1963) John Locke (1632–1704), physician and philosopher: a medical biography. Wellcome Historical Medical Library, London, p 6
14.
go back to reference Dewhurst K (1966) Dr Thomas Sydenham (1624–1689): his life and original writings. University of California Press, Berkeley, p 88, citing P.R.O., 30/24/47/2, ff. 33 r-v Dewhurst K (1966) Dr Thomas Sydenham (1624–1689): his life and original writings. University of California Press, Berkeley, p 88, citing P.R.O., 30/24/47/2, ff. 33 r-v
15.
go back to reference Dewhurst K (1983) Richard Lower’s vindicatio: a defence of the experimental method. Sandford Publications, Oxford p 284 (in text p 184) Dewhurst K (1983) Richard Lower’s vindicatio: a defence of the experimental method. Sandford Publications, Oxford p 284 (in text p 184)
16.
go back to reference Dow RS (1940) Thomas Willis (1621–1675) as a comparative neurologist. Ann Med Hist 2:181–185 Dow RS (1940) Thomas Willis (1621–1675) as a comparative neurologist. Ann Med Hist 2:181–185
17.
go back to reference Ebstein W (1866) Über einen sehr seltenen Fall von Insufficienz der Valvula tricuspidalis, bedingt durch eine angeborene hochgradige Missbildung derselben. Archiv für Anatomie, Physiologie und wissenschaftliche Medicin, Leipzig, pp 238–254 Ebstein W (1866) Über einen sehr seltenen Fall von Insufficienz der Valvula tricuspidalis, bedingt durch eine angeborene hochgradige Missbildung derselben. Archiv für Anatomie, Physiologie und wissenschaftliche Medicin, Leipzig, pp 238–254
18.
go back to reference Fleming PA (1997) Short history of cardiology. Editions Rodopi BV, Amsterdam, p 1 Fleming PA (1997) Short history of cardiology. Editions Rodopi BV, Amsterdam, p 1
19.
go back to reference French R (1989) Harvey in Holland; circulation and the Calvanists. In: French R, Wear A (eds) The medical revolution of the seventeenth century. Cambridge, pp 66–67 French R (1989) Harvey in Holland; circulation and the Calvanists. In: French R, Wear A (eds) The medical revolution of the seventeenth century. Cambridge, pp 66–67
20.
go back to reference French R (1993) The anatomical tradition. In: Bynum WF, Porter R (eds) Companion encyclopedia of the history of medicine, vol 1. London, pp 88–89 French R (1993) The anatomical tradition. In: Bynum WF, Porter R (eds) Companion encyclopedia of the history of medicine, vol 1. London, pp 88–89
21.
go back to reference French R (1994) William Harvey’s natural philosophy. Cambridge, pp 341–345 French R (1994) William Harvey’s natural philosophy. Cambridge, pp 341–345
22.
go back to reference Glisson F (1650) De Rachidite, cited in Ruhrär J (1925) Pediatrics of the past. New York, pp 260–284 Glisson F (1650) De Rachidite, cited in Ruhrär J (1925) Pediatrics of the past. New York, pp 260–284
23.
go back to reference Gunther RT (1969) Early science in Oxford. vol 9. De Corde by Richard Lower, London. Introduction and translation by K. J. Franklin, chapter 111 Movement and Colour of the Blood Oxford 1932 pp 167–168 and p 170 Gunther RT (1969) Early science in Oxford. vol 9. De Corde by Richard Lower, London. Introduction and translation by K. J. Franklin, chapter 111 Movement and Colour of the Blood Oxford 1932 pp 167–168 and p 170
24.
go back to reference Gunther RT (1969) Early science in Oxford. vol 9. De Corde by Richard Lower, London. Introduction and translation by K. J. Franklin, chapter 111 Movement and Colour of the Blood Oxford 1932, pp 54–55 Gunther RT (1969) Early science in Oxford. vol 9. De Corde by Richard Lower, London. Introduction and translation by K. J. Franklin, chapter 111 Movement and Colour of the Blood Oxford 1932, pp 54–55
25.
go back to reference Guthrie D (1946) A history of medicine. Thomas Nelson and Sons, London, p 188 Guthrie D (1946) A history of medicine. Thomas Nelson and Sons, London, p 188
26.
go back to reference Harrison J, Laslett P (eds) (1971) The library of John Locke. 2nd ed. Oxford, p 179 Harrison J, Laslett P (eds) (1971) The library of John Locke. 2nd ed. Oxford, p 179
27.
go back to reference Dr Edmund Meara to Locke 2 January 1661 The Correspondence of John Locke. edited by de Beer, Clarendon Press, Oxford: 1989: Vol 1 p 163 Dr Edmund Meara to Locke 2 January 1661 The Correspondence of John Locke. edited by de Beer, Clarendon Press, Oxford: 1989: Vol 1 p 163
28.
go back to reference Letter Locke to Dr (later Sir) Thomas Molyneux 20 January 1693. The Correspondence of John Locke. edited by de Beer, Clarendon Press, Oxford: 1989.: vol 4. pp 629–630 Letter Locke to Dr (later Sir) Thomas Molyneux 20 January 1693. The Correspondence of John Locke. edited by de Beer, Clarendon Press, Oxford: 1989.: vol 4. pp 629–630
30.
go back to reference Lower R (1665) Diatribae Thomae Willisii de febribus vindicaton adversus Edmundum de Meara. Maryn and Allestry, London, quoted on pp 256–257, a facsimile edition introduced and edited by Kenneth Dewhurst. Oxford: Sandford, 1983 Lower R (1665) Diatribae Thomae Willisii de febribus vindicaton adversus Edmundum de Meara. Maryn and Allestry, London, quoted on pp 256–257, a facsimile edition introduced and edited by Kenneth Dewhurst. Oxford: Sandford, 1983
31.
go back to reference Malpighi M (1661) De pulmonibus epistolae!! ad borellium. Bologna Malpighi M (1661) De pulmonibus epistolae!! ad borellium. Bologna
33.
go back to reference O’Rourke Boyle M (2008) William Harvey’s soliloquy to the College of Physicians: reprising Terence’s plot. Med Hist 52:365–386, citing Harvey W (1628) Excitatio anatomica de motu cordis et sanguinis in animalibus. Frankfurt, p 21 O’Rourke Boyle M (2008) William Harvey’s soliloquy to the College of Physicians: reprising Terence’s plot. Med Hist 52:365–386, citing Harvey W (1628) Excitatio anatomica de motu cordis et sanguinis in animalibus. Frankfurt, p 21
34.
go back to reference Osler W (1900) John Locke as a physician. Lancet, p 1116 Osler W (1900) John Locke as a physician. Lancet, p 1116
35.
go back to reference Porter R (1997) The greatest benefit to mankind: a medical history of humanity from antiquity to the present. HarperCollins Publishers, London, p 218 Porter R (1997) The greatest benefit to mankind: a medical history of humanity from antiquity to the present. HarperCollins Publishers, London, p 218
36.
go back to reference Porter R (1997) The greatest benefit to mankind. Harper Collins, London, p 220 Porter R (1997) The greatest benefit to mankind. Harper Collins, London, p 220
37.
go back to reference Porter R (1997) The greatest benefit to mankind a medical history of humanity from antiquity to the present. Harper Collins, London, p 243 Porter R (1997) The greatest benefit to mankind a medical history of humanity from antiquity to the present. Harper Collins, London, p 243
38.
go back to reference Primrose J (1640) Animadversiones in theses, quas pro circulatione sanguinis in academiâ ultrajectensi D. Henricus le Roy, ibidem medicinae professor, disputandas proposuit (preface). Leyden Primrose J (1640) Animadversiones in theses, quas pro circulatione sanguinis in academiâ ultrajectensi D. Henricus le Roy, ibidem medicinae professor, disputandas proposuit (preface). Leyden
39.
go back to reference Rather LJ (1974) Pathology at mid-century: a reassessment of Thomas Willis and Thomas Sydenham. In: Debus AG (ed) Medicine in seventeenth-century England, Berkeley, pp 73–76 Rather LJ (1974) Pathology at mid-century: a reassessment of Thomas Willis and Thomas Sydenham. In: Debus AG (ed) Medicine in seventeenth-century England, Berkeley, pp 73–76
40.
go back to reference Romanell P (1984) John Locke and medicine. Prometheus books, New York Romanell P (1984) John Locke and medicine. Prometheus books, New York
42.
go back to reference Shane Tubbs R, Loukas M, Shoja MM, Ardalan MR, Okaes WJ (2008) Richard Lower (1631–1691 and his early contribution to cardiology. Int J Cardiol 128:17–21PubMedCrossRef Shane Tubbs R, Loukas M, Shoja MM, Ardalan MR, Okaes WJ (2008) Richard Lower (1631–1691 and his early contribution to cardiology. Int J Cardiol 128:17–21PubMedCrossRef
43.
go back to reference Singer C (1957) A short history of anatomy and physiology from the Greeks to Harvey. Dover, pp 46–62, 182–183 Singer C (1957) A short history of anatomy and physiology from the Greeks to Harvey. Dover, pp 46–62, 182–183
44.
go back to reference Walmsley P (2007) John Locke on respiration. Med Hist 51:464 Walmsley P (2007) John Locke on respiration. Med Hist 51:464
45.
go back to reference Walmsley P (2007) John Locke on respiration. Med Hist 51:453–476 Walmsley P (2007) John Locke on respiration. Med Hist 51:453–476
46.
go back to reference Wear A (1989) Medical practice in late seventeenth- and early eighteenth-century England: continuity and union. In: French R, Wear A (eds) The medical revolution of the seventeenth century. Cambridge, pp 294–320 Wear A (1989) Medical practice in late seventeenth- and early eighteenth-century England: continuity and union. In: French R, Wear A (eds) The medical revolution of the seventeenth century. Cambridge, pp 294–320
47.
go back to reference Wear A (2000) Knowledge & practice in English medicine, 1550–1680. Cambridge, p 5 and chapter 10 Wear A (2000) Knowledge & practice in English medicine, 1550–1680. Cambridge, p 5 and chapter 10
48.
go back to reference Wear A (2000) Knowledge & practice in English medicine, 1550–1680. Cambridge, pp 358–359 Wear A (2000) Knowledge & practice in English medicine, 1550–1680. Cambridge, pp 358–359
49.
go back to reference Wear A (2000) Knowledge & practice in English medicine, 1550–1680. Cambridge, chapters 9 and 10 Wear A (2000) Knowledge & practice in English medicine, 1550–1680. Cambridge, chapters 9 and 10
50.
go back to reference Williams AN, Wilson N, Sunderland R (2009) Philosopher, pediatrician, pathologist? John Locke’s thoughts on rhicketts and a missed case of Ebstein’s anomaly. Pediatr Cardiol 30:191–193PubMedCrossRef Williams AN, Wilson N, Sunderland R (2009) Philosopher, pediatrician, pathologist? John Locke’s thoughts on rhicketts and a missed case of Ebstein’s anomaly. Pediatr Cardiol 30:191–193PubMedCrossRef
Metadata
Title
John Locke, “Rhickets” and the Cardiopulmonary Circulation
Author
A. N. Williams
Publication date
01-01-2012
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 1/2012
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-011-0100-z

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