Published in:
01-03-2015 | Editor’s Commentary
Is there an appropriate time to initiate the rehabilitation of human gametes destined for human ARTs?
Author:
David F. Albertini
Published in:
Journal of Assisted Reproduction and Genetics
|
Issue 3/2015
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Excerpt
It is an unavoidable tenet in the practice of human ARTs that at some stage or another, gametes will be collected and united ex vivo with the expressed purpose of generating embryos. Whether those embryos will carry with them the toolkit that endows them with the ability to attach to the endometrium, effect implantation, and propagate a maternal environment conducive to the support of a term gestation is another matter altogether. In fact, few amongst us would doubt the importance of the embryonic toolkit nor would doubts be raised that the toolkit itself is comprised of assorted devices that arose during the differentiation and maturation of eggs and sperm. Think mitochondria, centrioles, chromosomes, gap junctions, and ribosomes to name a few. …