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Published in: BMC Health Services Research 1/2004

Open Access 01-12-2004 | Research article

Is there a clinically significant seasonal component to hospital admissions for atrial fibrillation?

Authors: Ross EG Upshur, Rahim Moineddin, Eric J Crighton, Muhammad Mamdani

Published in: BMC Health Services Research | Issue 1/2004

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Abstract

Background

Atrial fibrillation is a common cardiac dysrhythmia, particularly in the elderly. Recent studies have indicated a statistically significant seasonal component to atrial fibrillation hospitalizations.

Methods

We conducted a retrospective population cohort study using time series analysis to evaluate seasonal patterns of atrial fibrillation hospitalizations for the province of Ontario for the years 1988 to 2001. Five different series methods were used to analyze the data, including spectral analysis, X11, R-Squared, autocorrelation function and monthly aggregation.

Results

This study found evidence of weak seasonality, most apparent at aggregate levels including both ages and sexes. There was dramatic increase in hospitalizations for atrial fibrillation over the years studied and an age dependent increase in rates per 100,000. Overall, the magnitude of seasonal difference between peak and trough months is in the order of 1.4 admissions per 100,000 population. The peaks for hospitalizations were predominantly in April, and the troughs in August.

Conclusions

Our study confirms statistical evidence of seasonality for atrial fibrillation hospitalizations. This effect is small in absolute terms and likely not significant for policy or etiological research purposes.
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Literature
1.
2.
go back to reference Go AS, Hylek EM, Phillips KA, Chang Y, Henault LE, Selby JV, Singer DE: Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA. 2001, 285: 2370-2375. 10.1001/jama.285.18.2370.CrossRefPubMed Go AS, Hylek EM, Phillips KA, Chang Y, Henault LE, Selby JV, Singer DE: Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA. 2001, 285: 2370-2375. 10.1001/jama.285.18.2370.CrossRefPubMed
3.
go back to reference Viskin S, Golovner M, Malov N, Fish R, Alroy I, Vila Y, Laniado S, Kaplinsky E, Roth A: Circadian variation of symptomatic paroxysmal atrial fibrillation. Data from almost 10 000 episodes. Eur Heart J. 1999, 20: 1429-1434. 10.1053/euhj.1999.1632.CrossRefPubMed Viskin S, Golovner M, Malov N, Fish R, Alroy I, Vila Y, Laniado S, Kaplinsky E, Roth A: Circadian variation of symptomatic paroxysmal atrial fibrillation. Data from almost 10 000 episodes. Eur Heart J. 1999, 20: 1429-1434. 10.1053/euhj.1999.1632.CrossRefPubMed
4.
go back to reference Kupari M, Koskinen P: Seasonal variation in occurrence of acute atrial fibrillation and relation to air temperature and sale of alcohol. Am J Cardiol. 1990, 66: 1519-1520.CrossRefPubMed Kupari M, Koskinen P: Seasonal variation in occurrence of acute atrial fibrillation and relation to air temperature and sale of alcohol. Am J Cardiol. 1990, 66: 1519-1520.CrossRefPubMed
5.
go back to reference Frost L, Johnsen SP, Pedersen L, Husted S, Engholm G, Sorensen HT, Rothman KJ: Seasonal variation in hospital discharge diagnosis of atrial fibrillation: a population-based study. Epidemiology. 2002, 13: 211-215. 10.1097/00001648-200203000-00017.CrossRefPubMed Frost L, Johnsen SP, Pedersen L, Husted S, Engholm G, Sorensen HT, Rothman KJ: Seasonal variation in hospital discharge diagnosis of atrial fibrillation: a population-based study. Epidemiology. 2002, 13: 211-215. 10.1097/00001648-200203000-00017.CrossRefPubMed
6.
go back to reference Jenkins G, Watts D: Spectral analysis and its applications. 1968, San Francisco: Holden Day Jenkins G, Watts D: Spectral analysis and its applications. 1968, San Francisco: Holden Day
7.
go back to reference Priestly M: Spectral analysis and time Series. 1981, New York: Academic Press, Inc Priestly M: Spectral analysis and time Series. 1981, New York: Academic Press, Inc
8.
go back to reference Bell W, Hillmer S: Issues involved with the seasonal adjustment of economic time series. Journal of Business & Economic Statistics. 1984, 2: 291-320. Bell W, Hillmer S: Issues involved with the seasonal adjustment of economic time series. Journal of Business & Economic Statistics. 1984, 2: 291-320.
9.
go back to reference SAS/ETS user's guide version 8. 1999, Cary, NC: SAS Institute Inc SAS/ETS user's guide version 8. 1999, Cary, NC: SAS Institute Inc
10.
go back to reference Box G, Jenkins G: Time series analysis: forecasting and control. 1976, San Francisco: Holden-Day Box G, Jenkins G: Time series analysis: forecasting and control. 1976, San Francisco: Holden-Day
11.
go back to reference Moineddin R, Upshur RE, Crighton E, Mamdani M: Autoregression as a means of assessing the strength of seasonality in a time series. Popul Health Metr. 2003, 1: 10-10.1186/1478-7954-1-10.CrossRefPubMedPubMedCentral Moineddin R, Upshur RE, Crighton E, Mamdani M: Autoregression as a means of assessing the strength of seasonality in a time series. Popul Health Metr. 2003, 1: 10-10.1186/1478-7954-1-10.CrossRefPubMedPubMedCentral
12.
go back to reference Upshur RE, Knight K, Goel V: Time-series analysis of the relation between influenza virus and hospital admissions of the elderly in Ontario, Canada, for pneumonia, chronic lung disease, and congestive heart failure. Am J Epidemiol. 1999, 149: 85-92.CrossRefPubMed Upshur RE, Knight K, Goel V: Time-series analysis of the relation between influenza virus and hospital admissions of the elderly in Ontario, Canada, for pneumonia, chronic lung disease, and congestive heart failure. Am J Epidemiol. 1999, 149: 85-92.CrossRefPubMed
13.
go back to reference Crighton EJ, Mamdani MM, Upshur RE: A population based time series analysis of asthma hospitalisations in Ontario, Canada: 1988 to 2000. BMC Health Serv Res. 2001, 1: 7-10.1186/1472-6963-1-7.CrossRefPubMedPubMedCentral Crighton EJ, Mamdani MM, Upshur RE: A population based time series analysis of asthma hospitalisations in Ontario, Canada: 1988 to 2000. BMC Health Serv Res. 2001, 1: 7-10.1186/1472-6963-1-7.CrossRefPubMedPubMedCentral
14.
go back to reference Mamdani MM, Upshur RE: Fall-related hospitalizations: what's in season?. Can J Public Health. 2001, 92: 113-116.PubMed Mamdani MM, Upshur RE: Fall-related hospitalizations: what's in season?. Can J Public Health. 2001, 92: 113-116.PubMed
15.
go back to reference Crighton EJ, Moineddin R, Upshur RE, Mamdani M: The seasonality of total hospitalizations in Ontario by age and gender: a time series analysis. Can J Public Health. 2003, 94: 453-457.PubMed Crighton EJ, Moineddin R, Upshur RE, Mamdani M: The seasonality of total hospitalizations in Ontario by age and gender: a time series analysis. Can J Public Health. 2003, 94: 453-457.PubMed
Metadata
Title
Is there a clinically significant seasonal component to hospital admissions for atrial fibrillation?
Authors
Ross EG Upshur
Rahim Moineddin
Eric J Crighton
Muhammad Mamdani
Publication date
01-12-2004
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2004
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-4-5

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