Is Nodular Gastritis a Precancerous Condition?

Excerpt

I read with great interest the article by Hong et al. [1]. They analyzed clinico-epidemiological characteristics of 52 patients with nodular gastritis (NG) and 2,527 controls. Gastric neoplasm was detected in a single patient in the NG group (1.9 %) and in five patients in the control group (0.2 %). In this study NG was associated with increased gastric neoplasia, including gastric adenoma and adenocarcinoma based on multivariate analysis (odds ratio = 10.52, 95 % CI [1.20–92.0]). The authors stated that the clinical implication of this finding was unclear because the range of the 95 % CI was notably wide and a positive association between NG and gastric neoplasm could not be found in the subgroup analysis comparing the Helicobacter pylori (−) controls or H. pylori (+) controls [1]. …