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European Archives of Oto-Rhino-Laryngology

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Open Access 01-07-2010 | Editorial

Is it necessary to perform radical neck dissection as a salvage procedure for persistent or recurrent neck disease after chemoradiotherapy in patients with nasopharyngeal cancer?

Authors: Avi Khafif, Alfio Ferlito, Robert P. Takes, K. Thomas Robbins

Published in: European Archives of Oto-Rhino-Laryngology | Issue 7/2010

Excerpt

Nasopharyngeal carcinoma (NPC) is well known for its high propensity for nodal metastases and in up to 70% of the patients cervical lymphadenopathy may be the presenting symptom. Following standard treatment with radiotherapy or a combination of chemotherapy and radiotherapy most patients with NPC are cured from their disease. However, persistent or recurrent nodal disease following the initial treatment is not uncommon. The treatment of such persistent or recurrent neck disease following radiotherapy with or without chemotherapy is controversial. …

Khoo ML, Soo KC, Lim DT, Fong KW, Goh CH, Sethi DS (1999) The pattern of nodal recurrence following definitive radiotherapy for nasopharyngeal carcinoma. Aust N Z J Surg 69:354–356CrossRefPubMed

King AD, Ahuja AT, Leung SF, Lam WW, Teo P, Chan YL, Metreweli C (2000) Neck node metastases from nasopharyngeal carcinoma: MR imaging of patterns of disease. Head Neck 22:275–281CrossRefPubMed

Ahuja AT, Leung SF, Teo P, Ying M, King W, Metreweli C (1999) Submental metastases from nasopharyngeal carcinoma. Clin Radiol 54:25–28CrossRefPubMed

Wei EI, Ho CM, Wong MP, Ng WF, Lau SK, Lam KH (1992) Pathological basis of surgery in the management of postradiotherapy cervical metastasis in nasopharyngeal carcinoma. Arch Otolaryngol Head Neck Surg 118:923–929, discussion 930

Wei WI, Ho WK, Cheng AC, Wu X, Li GK, Nicholls J, Yuen PW, Sham JS (2001) Management of extensive cervical nodal metastasis in nasopharyngeal carcinoma after radiotherapy: a clinicopathological study. Arch Otolaryngol Head Neck Surg 127:1457–1462PubMed

Wei WI, Mok VW (2007) The management of neck metastases in nasopharyngeal cancer. Curr Opin Otolaryngol Head Neck Surg 15:99–102CrossRefPubMed

Yen KL, Hsu LP, Sheen TS, Chang YL, Hsu MH (1997) Salvage neck dissection for cervical recurrence of nasopharyngeal carcinoma. Arch Otolaryngol Head Neck Surg 123:725–729PubMed

Xia LP, Zeng ZY, Chen ZH, Guo ZM, Guo X, Zhang Q (2005) Surgery for the recurrent and persistent lymph node of nasopharyngeal carcinoma after radiotherapy. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 40:95–99 (in Chinese)PubMed

Ferlito A, Kowalski LP, Silver CE, Shaha AR, Rinaldo A, Byers RM (2002) The use and misuse of level IA dissection for head and neck cancer. Acta Otolaryngol 122:553–555CrossRefPubMed

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Ferlito A, Rinaldo A (2008) Is radical neck dissection a current option for neck disease? Laryngoscope 118:1717–1718CrossRefPubMed

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Ferlito A, Corry J, Silver CE, Shaha AR, Robbins KT, Rinaldo A (2010) Planned neck dissection for patients with complete response to chemoradiotherapy: a concept approaching obsolescence. Head Neck 32:253–261PubMed

Title: Is it necessary to perform radical neck dissection as a salvage procedure for persistent or recurrent neck disease after chemoradiotherapy in patients with nasopharyngeal cancer?
Authors: Avi Khafif
Alfio Ferlito
Robert P. Takes
K. Thomas Robbins
Publication date: 01-07-2010
Publisher: Springer-Verlag
Published in: European Archives of Oto-Rhino-Laryngology / Issue 7/2010
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-010-1235-x

Keynote webinar | Spotlight on medication adherence

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Is it necessary to perform radical neck dissection as a salvage procedure for persistent or recurrent neck disease after chemoradiotherapy in patients with nasopharyngeal cancer?

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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