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World Journal of Surgical Oncology

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Open Access 01-12-2014 | Research

Is concomitant splenectomy beneficial for the long-term survival of patients with gastric cancer undergoing curative gastrectomy? A single-institution study

Authors: Hao Zhang, Deyan Pang, Huanming Xu, Yuan Ren, Caigang Liu

Published in: World Journal of Surgical Oncology | Issue 1/2014

Abstract

Background

Curative resection is the treatment of choice for gastric cancer, but it is unclear whether gastrectomy should also include splenectomy. We retrospectively analyzed long-term survival in patients in our hospital who underwent gastrectomy plus splenectomy (G + S) or gastrectomy alone (G-A) for gastric cancer.

Methods

We identified 214 patients who underwent surgery with curative intent between 1980 and 2003. Of these, 100 underwent G + S, and 114 underwent G-A. The primary endpoint was 5-year overall survival (OS).

Results

Median follow-up was 18 months in patients who underwent G + S, and 26.5 months in patients who underwent G-A. The 5-year OS rate was significantly higher in patients who underwent G-A (33.8%; 95% CI 24.2 to 43.4%) than in those who underwent G + S (28.8%; 95% CI 19.6 to 38.0%) (log-rank test, P = 0.013).

Conclusions

Splenectomy does not benefit patients undergoing gastrectomy for gastric cancer. Routine splenectomy should be abandoned in patients undergoing radical resections for gastric cancer.

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Title: Is concomitant splenectomy beneficial for the long-term survival of patients with gastric cancer undergoing curative gastrectomy? A single-institution study
Authors: Hao Zhang
Deyan Pang
Huanming Xu
Yuan Ren
Caigang Liu
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2014
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-12-193

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Is concomitant splenectomy beneficial for the long-term survival of patients with gastric cancer undergoing curative gastrectomy? A single-institution study

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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