Skip to main content
Top
Published in: World Journal of Surgical Oncology 1/2016

Open Access 01-12-2016 | Case report

Iris metastasis of gastric adenocarcinoma

Authors: Ali Riza Cenk Celebi, Ayse Ebru Kilavuzoglu, U. Emrah Altiparmak, C. Banu Cosar, Abdullah Ozkiris

Published in: World Journal of Surgical Oncology | Issue 1/2016

Login to get access

Abstract

Background

Iris metastasis in patients with gastric cancer is extremely rare. Herein, it is aimed to report on a patient with gastric adenocarcinoma and iris metastasis.

Case presentation

A 65-year-old patient with the history of gastric cancer was admitted for eye pain and eye redness on his left eye. There was ciliary injection, severe +4 cells with hypopyon in the anterior chamber and a solitary, friable, yellow-white, fleshy-creamy vascularized 2 mm × 4 mm mass on the upper nasal part of the iris within the left eye. The presented patient’s mass lesion in the iris fulfilled the criteria of the metastatic iris lesion’s appearance. The ocular metastasis occurred during chemotherapy.

Conclusions

Iris metastasis can masquerade as iridocyclitis with pseudohypopyon or glaucoma. In patients with a history of gastric cancer that present with an iris mass, uveitis, and high intraocular pressure, ocular metastasis of gastric cancer should be a consideration.
Literature
1.
go back to reference Bloch RS, Gartner S. The incidence of ocular metastatic carcinoma. Arch Ophthalmol. 1971;85:673–5.CrossRefPubMed Bloch RS, Gartner S. The incidence of ocular metastatic carcinoma. Arch Ophthalmol. 1971;85:673–5.CrossRefPubMed
2.
go back to reference Nelson CC, Hertzberg BS, Klintworth GK. A histopathologic study of 716 unselected eyes in patients with cancer at the time of death. Am J Ophthalmol. 1983;95:788–93.CrossRefPubMed Nelson CC, Hertzberg BS, Klintworth GK. A histopathologic study of 716 unselected eyes in patients with cancer at the time of death. Am J Ophthalmol. 1983;95:788–93.CrossRefPubMed
3.
go back to reference Shields CL, Shields JA, Gross NE, Schwartz GP, Lally SE. Survey of 520 eyes with uveal metastases. Ophthalmology. 1997;104:1265–76.CrossRefPubMed Shields CL, Shields JA, Gross NE, Schwartz GP, Lally SE. Survey of 520 eyes with uveal metastases. Ophthalmology. 1997;104:1265–76.CrossRefPubMed
4.
go back to reference Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. CA Cancer J Clin. 2001;61:69–90.CrossRef Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. CA Cancer J Clin. 2001;61:69–90.CrossRef
5.
go back to reference Kawai S, Nishida T, Hayashi Y, Ezaki H, Yamada T, Shinzaki S, et al. Choroidal and cutaneous metastasis from gastric adenocarcinoma. World J Gastroenterol. 2013;19:1485–8.CrossRefPubMedPubMedCentral Kawai S, Nishida T, Hayashi Y, Ezaki H, Yamada T, Shinzaki S, et al. Choroidal and cutaneous metastasis from gastric adenocarcinoma. World J Gastroenterol. 2013;19:1485–8.CrossRefPubMedPubMedCentral
6.
go back to reference Sahin A, Kiratli H. Choroidal metastasis as a first sign of recurrence in a patient with gastric adenocarcinoma. Can J Ophthalmol. 2007;42:331–2.CrossRefPubMed Sahin A, Kiratli H. Choroidal metastasis as a first sign of recurrence in a patient with gastric adenocarcinoma. Can J Ophthalmol. 2007;42:331–2.CrossRefPubMed
7.
go back to reference Liszauer AD, Wiens JJ, Brownstein S, Deschênes J. Gastric linitis plastica metastatic to the uvea. Can J Ophthalmol. 1991;26:325–7.PubMed Liszauer AD, Wiens JJ, Brownstein S, Deschênes J. Gastric linitis plastica metastatic to the uvea. Can J Ophthalmol. 1991;26:325–7.PubMed
8.
go back to reference Shields CL, Kaliki S, Crabtree GS, Peshtani A, Morton S, Anand RA, et al. Iris metastasis from systemic cancer in 104 patients: the 2014 Jerry A. Shields Lecture. Cornea. 2015;34:42–8.CrossRefPubMed Shields CL, Kaliki S, Crabtree GS, Peshtani A, Morton S, Anand RA, et al. Iris metastasis from systemic cancer in 104 patients: the 2014 Jerry A. Shields Lecture. Cornea. 2015;34:42–8.CrossRefPubMed
9.
go back to reference Imamura Y, Suzuki M, Nakajima KI, Murata H. Gastric signet ring cell adenocarcinoma metastatic to the iris. Am J Ophthalmol. 2001;131:379–81.CrossRefPubMed Imamura Y, Suzuki M, Nakajima KI, Murata H. Gastric signet ring cell adenocarcinoma metastatic to the iris. Am J Ophthalmol. 2001;131:379–81.CrossRefPubMed
10.
go back to reference Ferry AP, Font RL. Carcinoma metastatic to the eye and orbit. I. A clinicopathologic study of 227 cases. Arch Ophthalmol. 1974;92:276–86.CrossRefPubMed Ferry AP, Font RL. Carcinoma metastatic to the eye and orbit. I. A clinicopathologic study of 227 cases. Arch Ophthalmol. 1974;92:276–86.CrossRefPubMed
11.
go back to reference Ichiki Y, Morita M, Yano K, Sugio K, Yasumoto K, Hirose N. Iris metastasis of esophageal cancer. Ann Thorac Surg. 2005;79:1782–4.CrossRefPubMed Ichiki Y, Morita M, Yano K, Sugio K, Yasumoto K, Hirose N. Iris metastasis of esophageal cancer. Ann Thorac Surg. 2005;79:1782–4.CrossRefPubMed
12.
13.
go back to reference Küchle M, Holbach L, Schlötzer-Schrehardt U. Gastric adenocarcinoma presenting as an eyelid and conjunctival mass. Eur J Ophthalmol. 1992;2:3–9.PubMed Küchle M, Holbach L, Schlötzer-Schrehardt U. Gastric adenocarcinoma presenting as an eyelid and conjunctival mass. Eur J Ophthalmol. 1992;2:3–9.PubMed
14.
go back to reference Sung JU, Lam BL, Curtin VT, Tse DT. Metastatic gastric carcinoma to the optic nerve. Arch Ophthalmol. 1998;116:692–3.CrossRefPubMed Sung JU, Lam BL, Curtin VT, Tse DT. Metastatic gastric carcinoma to the optic nerve. Arch Ophthalmol. 1998;116:692–3.CrossRefPubMed
15.
go back to reference Shields JA, Shields CL, Kiratli H, de Potter P. Metastatic tumors to the iris in 40 patients. Am J Ophthalmol. 1995;119:422–30.CrossRefPubMed Shields JA, Shields CL, Kiratli H, de Potter P. Metastatic tumors to the iris in 40 patients. Am J Ophthalmol. 1995;119:422–30.CrossRefPubMed
Metadata
Title
Iris metastasis of gastric adenocarcinoma
Authors
Ali Riza Cenk Celebi
Ayse Ebru Kilavuzoglu
U. Emrah Altiparmak
C. Banu Cosar
Abdullah Ozkiris
Publication date
01-12-2016
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2016
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-016-0840-6

Other articles of this Issue 1/2016

World Journal of Surgical Oncology 1/2016 Go to the issue