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01-03-2019 | Original Article

Iodonium salt incorporation in dental adhesives and its relation with degree of conversion, ultimate tensile strength, cell viability, and oxidative stress

Authors: Camila Perelló Ferrúa, Fernanda Barbosa Leal, Marta de Oliveira Gazal, Gabriele Cordenonzi Ghisleni, Rodrigo Varella de Carvalho, Flávio Fernando Demarco, Fabrício Aulo Ogliari, Fernanda Nedel

Published in: Clinical Oral Investigations | Issue 3/2019

Abstract

Objective

The aim of this study was to evaluate the degree of conversion, ultimate tensile strength, cell viability, and oxidative stress of two different ternary initiation systems, using two photoinitiation polymerization times.

Methods

The groups investigated were camphorquinone (CQ); CQ and diphenyleneiodonium hexafluorophosphate (DPI); CQ and ethyl 4-dimethylamine benzoate (EDAB); and CQ, EDAB, and DPI, with EDAB in high and low concentration. To assess the degree of conversion (DC) and the ultimate tensile strength (UTS), a real-time Fourier transform infrared spectroscopy and a universal test machine Emic DL-500 were used, respectively. Cell viability and oxidative stress were evaluated by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), superoxide dismutase (SOD), total sulfhydryl (SH) content, and thiobarbituric acid reactive species (TBARS) formation assays.

Results

Slight lower cell viability was shown when DPI was associated with high concentrations of EDAB; this reduction seemed to be attenuated when lower concentrations of EDAB were used. When EDAB and DPI were associated, no oxidative damage was shown. The degree of conversion was increased in the ternary systems (CQ + EDAB lower concentration + DPI) group, which did not affect the UTS, cytotoxicity, and oxidative stress parameters. The polymerization time did not affect cell viability, total SH, and TBARS; however, a slight increase was shown in SOD levels.

Clinical relevance

Our study emphasizes the relevance of incorporating the third element—iodonium salt—in a binary adhesive systems composed exclusively of CQ and EDAB.

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Title: Iodonium salt incorporation in dental adhesives and its relation with degree of conversion, ultimate tensile strength, cell viability, and oxidative stress
Authors: Camila Perelló Ferrúa
Fernanda Barbosa Leal
Marta de Oliveira Gazal
Gabriele Cordenonzi Ghisleni
Rodrigo Varella de Carvalho
Flávio Fernando Demarco
Fabrício Aulo Ogliari
Fernanda Nedel
Publication date: 01-03-2019
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 3/2019
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-018-2527-6

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Springer Medicine

Iodonium salt incorporation in dental adhesives and its relation with degree of conversion, ultimate tensile strength, cell viability, and oxidative stress

Abstract

Objective

Methods

Results

Clinical relevance

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Clinical relevance

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