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01-03-2019 | Original Article

Bone tissue reaction, setting time, solubility, and pH of root repair materials

Authors: Ramiro Martins Quintana, Alexander Pompermayer Jardine, Tuane Regina Grechi, Renata Grazziotin-Soares, Diego Machado Ardenghi, Roberta Kochenborger Scarparo, Fabiana Soares Grecca, Patrícia Maria Poli Kopper

Published in: Clinical Oral Investigations | Issue 3/2019

Abstract

Objectives

This study aims to compare the bone tissue reaction, setting time, solubility, and pH of NeoMTA Plus, Biodentine (BD), and MTA Angelus (MTA-A).

Materials and methods

Initial and final setting times (n = 7) and solubility up to 7 days (n = 11) were evaluated in accordance with ASTM C266–15 and ANSI/ADA Specification No. 57, respectively. pH (n = 10) was measured up to 28 days. Bone tissue reactions in 48 rats’ femur were histologically analyzed after 7, 30, and 90 days. ANOVA and Tukey’s tests compared setting time, solubility, and pH data; bone reactions data were compared by Kruskal-Wallis and Dunn’s tests.

Results

NeoMTA Plus had longer initial and final setting times than MTA-A and BD (P < 0.05). At 7 days, BD showed the highest solubility, similar to NeoMTA Plus (P > 0.05) and different from MTA-A (P < 0.05). NeoMTA Plus had a progressive mass loss over time; at 7 days, it was significantly different from the initial mass (P < 0.05). BD showed higher pH in the periods assessed when compared to the other materials (P < 0.05). Bone tissue repair had no differences between groups in each experimental period (P > 0.05). All groups presented no difference from 30 to 90 days (P > 0.05) and had better bone repair at 90 days than at 7 days (P < 0.05).

Conclusions

NeoMTA Plus, BD, and MTA-A showed satisfactory setting time, high mass loss, alkaline pH, and allowed bone repair.

Clinical relevance

Calcium silicate-based cements are indicated for multiple clinical situations. NeoMTA Plus and BD showed satisfactory physical-chemical and biological properties, being considered as alternatives to MTA-A, as root repair materials for clinical use.

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Title: Bone tissue reaction, setting time, solubility, and pH of root repair materials
Authors: Ramiro Martins Quintana
Alexander Pompermayer Jardine
Tuane Regina Grechi
Renata Grazziotin-Soares
Diego Machado Ardenghi
Roberta Kochenborger Scarparo
Fabiana Soares Grecca
Patrícia Maria Poli Kopper
Publication date: 01-03-2019
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 3/2019
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-018-2564-1

At a glance: The STEP trials

Springer Medicine

Bone tissue reaction, setting time, solubility, and pH of root repair materials

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

At a glance: The STEP trials

Springer Medicine

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

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