Published in:
01-06-2011 | Materno-fetal Medicine
Investigation of the factors affecting the perinatal outcome of monochorionic diamniotic twins
Authors:
Masahiro Murakami, Takeshi Iwasa, Machiko Kiyokawa, Yohei Takahashi, Mikio Morine
Published in:
Archives of Gynecology and Obstetrics
|
Issue 6/2011
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Abstract
Purpose
To investigate the factors affecting the perinatal outcome in monochorionic diamniotic (MD) twins.
Methods
We conducted a retrospective study of MD twins treated in our hospital between April 1, 2006 and February 28, 2010. The neonatal outcomes of MD twins conceived by assisted reproductive technology or ovulation induction were compared to the outcomes of those conceived naturally.
Results
In MD twins with twin-to-twin transfusion syndrome (TTTS), fetoscopic laser photocoagulation (FLP) resulted in the survival of at least one twin. In naturally conceived MD twins with two live births, we found that there was a higher discordance rate and the incidence of intrauterine growth retardation was higher in twins born to nulliparous women than multiparous women.
Conclusions
Further FLP treatment can be performed on twins with TTTS so that prognosis may be improved. Since the risk of discordant growth is significantly greater in twins of nulliparous women, they should be monitored more carefully than multiparous women.