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BMC Public Health
Published in: BMC Public Health 1/2024

Open Access 01-12-2024 | Research

Investigation of infant deaths associated with critical congenital heart diseases; 2018–2021, Türkiye

Authors: Nilgün Çaylan, Sıddika Songül Yalçin, Başak Tezel, Oben Üner, Şirin Aydin, Fatih Kara

Published in: BMC Public Health | Issue 1/2024

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Abstract

Background

The aim of this study was to examine the characteristics of infant mortality associated with critical congenital heart disease (CCHD).

Methods

In a cross-sectional study, data for the study were obtained through Death Notification System, Birth Notification System and Turkish Statistical Institute birth statistics.

Results

Of all infant deaths, 9.8% (4083) were associated with CCHD, and the infant mortality rate specific to CCHD was 8.8 per 10,000 live births. CCHD-related infant deaths accounted for 8.0% of all neonatal deaths, while the CCHD specific neonatal death rate was 4.6 per 10,000 live births. Of the deaths 21.7% occurred in the early neonatal, 30.3% in the late neonatal and 48.0% in the post neonatal period. Group 1 diseases accounted for 59.1% (n = 2415) of CCHD related infant deaths, 40.5% (n = 1652) were in Group 2 and 0.4% (n = 16) were in the unspecified group. Hypoplastic left heart syndrome was the most common CCHD among infant deaths (n = 1012; 24.8%). The highest CCHD related mortality rate was found in infants with preterm birth and low birth-weight while multiparity, maternal age ≥ 35 years, twin/triplet pregnancy, male gender, maternal education in secondary school and below, and cesarean delivery were also associated with higher CCHD related infant mortality rate. There was at least one non-cardiac congenital anomaly/genetic disorder in 26.1% of all cases.

Conclusion

CCHD holds a significant role in neonatal and infant mortality in Türkiye. To mitigate CCHD-related mortality rates, it is crucial to enhance prenatal diagnosis rates and promote widespread screening for neonatal CCHD.
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Metadata
Title
Investigation of infant deaths associated with critical congenital heart diseases; 2018–2021, Türkiye
Authors
Nilgün Çaylan
Sıddika Songül Yalçin
Başak Tezel
Oben Üner
Şirin Aydin
Fatih Kara
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2024
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-024-17966-4

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