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Journal of Anesthesia
Published in: Journal of Anesthesia 5/2012

01-10-2012 | Original Article

Intravenous ketamine compared with diclofenac suppository in suppressing acute postoperative pain in women undergoing gynecologic laparoscopy

Authors: Maryam Vosoughin, Shabnam Mohammadi, Ali Dabbagh

Published in: Journal of Anesthesia | Issue 5/2012

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Abstract

Purpose

We aimed to compare the analgesic effects of low-dose intravenous ketamine with the effects of diclofenac suppositories in acute postoperative pain management in women undergoing gynecologic laparoscopic surgery under general anesthesia.

Methods

In a double-blind, randomized clinical trial, 80 patients were selected and entered the study. After the induction of general anesthesia, one group received 0.15 mg/kg intravenous ketamine and the other group received a 100-mg rectal diclofenac suppository. The two groups were compared regarding acute pain scores, postoperative morphine requirements, and untoward complications.

Results

Pain scores and morphine requirements were lower in the rectal diclofenac suppository group at the 1st, 3rd, and 6th postoperative hours. Higher incidences of postoperative nausea and vomiting (PONV), delusions, and oral secretions were observed in the ketamine group.

Conclusions

Diclofenac 100-mg suppositories were more effective in suppressing acute pain than 0.15 mg/kg intravenous ketamine in women undergoing elective gynecologic laparoscopy, with fewer untoward complications.
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Metadata
Title
Intravenous ketamine compared with diclofenac suppository in suppressing acute postoperative pain in women undergoing gynecologic laparoscopy
Authors
Maryam Vosoughin
Shabnam Mohammadi
Ali Dabbagh
Publication date
01-10-2012
Publisher
Springer Japan
Published in
Journal of Anesthesia / Issue 5/2012
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-012-1399-1

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