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CardioVascular and Interventional Radiology

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01-05-2016 | Clinical Investigation

Intra-vesical Prostatic Protrusion (IPP) Can Be Reduced by Prostatic Artery Embolization

Authors: Yen-Ting Lin, Grégory Amouyal, Nicolas Thiounn, Olivier Pellerin, Héléna Pereira, Costantino Del Giudice, Carole Déan, Marc Sapoval

Published in: CardioVascular and Interventional Radiology | Issue 5/2016

Abstract

Background

Prostate artery embolization (PAE) is a new approach to improve lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia. PAE results in global reduction of prostate volume (PV). There are no data available on the efficacy of PAE in reducing intra-vesical prostatic protrusion (IPP), an anatomic feature that is clinically related with bladder outlet obstruction and LUTS.

Objective

To assess the results of PAE in patients with significant IPP due to median lobe hyperplasia and to compare the IPSS decrease and IPP change.

Material and Methods

Prospective analysis of 18 consecutive patients with significant IPP (>5 mm) related to median lobe hyperplasia undergoing PAE using 30–500-μm-calibrated trisacryl microspheres. We measured IPP on sagittal T2-weighted images before and 3 months after PAE. IPSS and clinical results were also evaluated at 3 months.

Results

PAE resulted in significant IPP reduction (1.57 cm ± 0.55 before PAE and 1.30 cm ± 0.46 after PAE, p = 0.0005) (Fig. 1) with no complication. IPSS, quality of life (QoL), total prostate-specific antigen (PSA) level, and PV showed significant reduction after PAE, and maximum urinary flow rate (Q _max) showed significant increase after PAE. No significant change of International Index of Erectile Function (IIEF) for clinical evaluation after PAE. A significant correlation was found between the IPP change and the IPSS change (r = 0.636, p = 0.0045).

Conclusion

Patients had significant IPP reduction as well as significant symptomatic improvement after PAE, and these improvements were positively correlated.

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Title: Intra-vesical Prostatic Protrusion (IPP) Can Be Reduced by Prostatic Artery Embolization
Authors: Yen-Ting Lin
Grégory Amouyal
Nicolas Thiounn
Olivier Pellerin
Héléna Pereira
Costantino Del Giudice
Carole Déan
Marc Sapoval
Publication date: 01-05-2016
Publisher: Springer US
Published in: CardioVascular and Interventional Radiology / Issue 5/2016
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-015-1235-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Intra-vesical Prostatic Protrusion (IPP) Can Be Reduced by Prostatic Artery Embolization

Abstract

Background

Objective

Material and Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Objective

Material and Methods

Results

Conclusion

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