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Supportive Care in Cancer

Published in:

01-01-2016 | Original Article

Interval versus continuous aerobic exercise training in breast cancer survivors—a pilot RCT

Authors: Lianne B. Dolan, Kristin Campbell, Karen Gelmon, Sarah Neil-Sztramko, Daniel Holmes, Donald C. McKenzie

Published in: Supportive Care in Cancer | Issue 1/2016

Abstract

Background

Exercise therapy is being explored in a variety of cancer populations to counteract treatment-related deconditioning. Higher intensity interval protocols are being prescribed to improve physical function and attenuate surrogates of comorbidity in non-cancer populations. The purpose of this study is to explore the safety of higher intensity exercise stimuli on cardiorespiratory fitness (VO_2peak) in breast cancer survivors.

Methods

Postmenopausal breast cancer survivors were randomized into three groups: supervised aerobic interval training (AIT), supervised continuous moderate exercise training (CMT), and an unsupervised control group (CON). For 6 weeks, AIT exercised between 70 and 100 % VO_2peak, while CMT exercised between 60 and 70 % VO_2peak. Both groups followed a matched-work design.

Results

Thirty-three participants completed the study (age, 57.2 (9) years; weight, 67.6 (12) kg) with no adverse advents. Between-group baseline values were non-significant. VO_2peak at baseline (25.3 (5.4) mL·kg⁻¹·min⁻¹) was below population norms. Compared to CON, cardiorespiratory fitness improved in AIT and CMT by 12 % (P < 0.001) with no significant difference between exercise groups. AIT had a greater influence on lower extremity strength (P = 0.026) and body weight (P = 0.031).

Conclusion

This pilot study provides evidence that similar to CMT, AIT can safely increase VO_2peak in a small group of breast cancer survivors. Further exploration of the benefits of implementing higher intensity training protocols is warranted.

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Title: Interval versus continuous aerobic exercise training in breast cancer survivors—a pilot RCT
Authors: Lianne B. Dolan
Kristin Campbell
Karen Gelmon
Sarah Neil-Sztramko
Daniel Holmes
Donald C. McKenzie
Publication date: 01-01-2016
Publisher: Springer Berlin Heidelberg
Published in: Supportive Care in Cancer / Issue 1/2016
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-015-2749-y

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Abstract

Background

Methods

Results

Conclusion

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