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Open Access 01-12-2022 | Insomnia | Research

Effect of insomnia in the major depressive disorder

Authors: Guohong Xu, Xiaoling Li, Caixia Xu, Guojun Xie, Jiaquan Liang

Published in: BMC Neurology | Issue 1/2022

Abstract

Background

People with sleep problems are more likely to have mental disorders. This study aimed to assess the effect of insomnia on the prognosis of patients with major depressive disorder (MDD).

Methods

We divided the patients into three groups according to the Insomnia Severity Index (ISI) scores. In addition, we compared the results of the Hamilton Depression Scale (HAMD) and Symptom Checklist-90 (SCL-90) scores. We evaluated the effect of insomnia at the 2nd, 4th, and 8th-week follow-up on the prognosis of MDD.

Results

Fifty-five patients between 19 and 58 years old, with a diagnosis of MDD via the Structured Clinical Interview for the Diagnostic and Statistical Manual-5 (DSM-5). The ISI scores of the moderate and severe group decreased significantly (P < 0.05) in the 2nd week compared to the baseline. The HAMD scores in all groups improved significantly in the 2nd week.

Conclusions

This study was inspired to assess insomnia as a comorbid disorder for patients with MDD, which may bring poor treatment consequences.

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Title: Effect of insomnia in the major depressive disorder
Authors: Guohong Xu
Xiaoling Li
Caixia Xu
Guojun Xie
Jiaquan Liang
Publication date: 01-12-2022
Publisher: BioMed Central
Keyword: Insomnia
Published in: BMC Neurology / Issue 1/2022
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-022-02869-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Effect of insomnia in the major depressive disorder

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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