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BMC Women's Health
Published in: BMC Women's Health 1/2024

Open Access 01-12-2024 | Injectable Filler | Case Report

Vulvar migration of injected polyacrylamide hydrogel following breast augmentation: a case report and literature review

Authors: Junxian Wen, Zhijin Li, Yarong Chi, Bo Chen, Tao Hong, Zhifei Liu, Nanze Yu, Xiaojun Wang

Published in: BMC Women's Health | Issue 1/2024

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Abstract

Background

Vulvar migration is a rare complication of filler injection for breast augmentation, generally presenting as repeated pain and fever. We will report a case of woman with polyacrylamide hydrogel breast injection develops vulvar abscess.

Case presentation

A woman with a history of polyacrylamide hydrogel breast injection was noted to have vulvar abscess due to migration of filler materials. Filler removal surgery and vacuum sealing drainage was performed for this patient. The patient was discharged from the hospital with no further complications. After a review of pertinent literature, only four previous case reports are found. Local inflammatory response, infection, large volume injections, inframammary fold destruction, hematogenous or lymphatic migrate, trauma, gravity and external pressure could play essential parts in the migration of injected filler.

Conclusion

Polyacrylamide hydrogel migration poses a worldwide challenge, necessitating personalized solutions. Our case study underscores the importance of comprehensive examinations for individuals with a history of filler breast injection when suspecting vulvar filler migration.
Appendix
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Literature
1.
2.
Coombs DM, Grover R, Prassinos A, Gurunluoglu R. Breast augmentation surgery: clinical considerations. Cleve Clin J Med. 2019;86(2):111–22.CrossRefPubMed
3.
4.
5.
6.
Son MJ, Ko KH, Jung HK, Koh JE, Park AY. Complications and radiologic features of breast augmentation via injection of Aquafilling Gel. J Ultrasound Med. 2018;37(7):1835–9.CrossRefPubMed
7.
Kim J, Chang H, Park JU. Complication of ruptured poly Implant Prothèse(®) breast implants combined with AQUAfilling(®) gel injection: a Case Report and Literature Review. Aesthetic Plast Surg. 2019;43(1):46–52.CrossRefPubMed
8.
Zhang MX, Li SY, Xu LL, Zhao BW, Cai XY, Wang GL. Repeated lumps and infections: a case report on breast augmentation complications. World J Clin Cases. 2019;7(20):3322–8.CrossRefPubMedPubMedCentral
9.
Jeng CJ, Ko ML, Wang TH, Huang SH. Vulvar siliconoma migrating from injected silicone breast augmentation. BJOG. 2005;112(12):1659–60.CrossRefPubMed
10.
Mouchati A, Yagoubi N. Mechanical performance and cytotoxicity of an Alginate/Polyacrylamide Bipolymer Network Developed for Medical applications. Mater (Basel) 2023, 16(5).
11.
Buzzaccarini G, Laganà AS, Borin M, Varì S, Tulipano G, Vertuè S, Noventa M, Albini M, Vercesi F. Los Deline copolyamide filler for breast and buttock augmentation. The position statement of the Italian Aesthetic Medicine Association (AMEI). J Plast Reconstr Aesthet Surg. 2022;75(8):2831–70.CrossRefPubMed
12.
Wang B, Sun J, Tong J. Breast contracture and skin sclerosis following 20 years of polyacrylamide hydrogel migration in a patient with familial vitiligo: a case report. BMC Surg. 2021;21(1):104.CrossRefPubMedPubMedCentral
13.
Unukovych D, Khrapach V, Wickman M, Liljegren A, Mishalov V, Patlazhan G, Sandelin K. Polyacrylamide gel injections for breast augmentation: management of complications in 106 patients, a multicenter study. World J Surg. 2012;36(4):695–701.CrossRefPubMed
14.
Chen B, Song H. Management of breast deformity after removal of Injectable Polyacrylamide Hydrogel: Retrospective Study of 200 cases for 7 years. Aesthetic Plast Surg. 2016;40(4):482–91.CrossRefPubMed
15.
Ding F, Zhao F, Jin R, Rao Y, Yang G, Lu L, Wang X, Sun D, Zhou X. Management of complications in 257 cases of breast augmentation with Polyacrylamide Hydrogel, using two different strategies: a retrospective study. Aesthetic Plast Surg. 2022;46(5):2107–21.CrossRefPubMed
16.
Maw AM, Sood S, Schembri GP. Case Report of 18F-FDG PET/CT Features of Polyacrylamide Hydrogel Mammoplasty. Clin Nucl Med. 2021;46(4):e206–7.CrossRefPubMed
17.
Woźniak-Roszkowska E, Maślińska M, Gierej P, Noszczyk B. Autoimmune syndrome induced by adjuvants after breast enhancement with polyacrylamide hydrogel: a study in Poland. Rheumatol Int. 2020;40(11):1851–6.CrossRefPubMedPubMedCentral
18.
Jin R, Luo X, Wang X, Ma J, Liu F, Yang Q, Yang J, Wang X. Complications and treatment strategy after breast augmentation by Polyacrylamide Hydrogel Injection: Summary of 10-Year clinical experience. Aesthetic Plast Surg. 2018;42(2):402–9.CrossRefPubMed
19.
Choi YJ, Lee IS, Song YS, Choi KU, Ahn HY. Distant migration of gel filler: imaging findings following breast augmentation. Skeletal Radiol. 2022;51(11):2223–7.CrossRefPubMed
20.
Khedher NB, David J, Trop I, Drouin S, Peloquin L, Lalonde L. Imaging findings of breast augmentation with injected hydrophilic polyacrylamide gel: patient reports and literature review. Eur J Radiol. 2011;78(1):104–11.CrossRefPubMed
21.
Wu J, Zhang X, Zhao Q, Mao D, Lu X. Vacuum sealing drainage in the treatment of migrated polyacrylamide hydrogel after breast augmentation: a case report. Breast Care (Basel). 2014;9(4):273–5.CrossRefPubMed
22.
Rish A. Polyacrylamide gel 10 years experience: with particular reference to complications from filling of the body of the lip. J Cosmet Dermatol. 2014;13(4):253–60.CrossRefPubMed
23.
Ishii H, Sakata K. Complications and management of breast enhancement using hyaluronic acid. Plast Surg (Oakv). 2014;22(3):171–4.CrossRefPubMed
24.
Duncan AM, Al Youha S, Joukhadar N, Konder R, Stecco C, Wheelock ME. Anatomy of the breast Fascial System: a systematic review of the literature. Plast Reconstr Surg. 2022;149(1):28–40.CrossRefPubMed
25.
Chen L, Sha L, Huang SP, Li SR, Wang ZX. Treatment for displacement of PAAG mixture after injection augmentation mammoplasty. Int J Clin Exp Med. 2015;8(3):3360–70.PubMedPubMedCentral
26.
Øvrebø Ø, Perale G, Wojciechowski JP, Echalier C, Jeffers JRT, Stevens MM, Haugen HJ, Rossi F. Design and clinical application of injectable hydrogels for musculoskeletal therapy. Bioeng Transl Med. 2022;7(2):e10295.CrossRefPubMedPubMedCentral
27.
Jung BK, Yun IS, Kim YS, Roh TS. Complication of AQUAfilling(®) gel injection for breast augmentation: Case Report of one case and review of literature. Aesthetic Plast Surg. 2018;42(5):1252–6.CrossRefPubMed
28.
Namgoong S, Kim HK, Hwang Y, Shin SH, You HJ, Kim DW, Kim A, Jung SP, Yoon ES. Clinical experience with treatment of Aquafilling Filler-Associated complications: a retrospective study of 146 cases. Aesthetic Plast Surg. 2020;44(6):1997–2007.CrossRefPubMed
29.
Alijotas-Reig J, Fernández-Figueras MT, Puig L. Late-onset inflammatory adverse reactions related to soft tissue filler injections. Clin Rev Allergy Immunol. 2013;45(1):97–108.CrossRefPubMed
30.
Luo SK, Chen GP, Sun ZS, Cheng NX. Our strategy in complication management of augmentation mammaplasty with polyacrylamide hydrogel injection in 235 patients. J Plast Reconstr Aesthet Surg. 2011;64(6):731–7.CrossRefPubMed
31.
Hallab NJ, Samelko L, Hammond D. The Inflammatory effects of breast Implant Particulate Shedding: comparison with Orthopedic implants. Aesthet Surg J. 2019;39(Suppl1):36–s48.CrossRef
32.
Dean RA, Glener AD, Thomas AB, Glener SR, Kurtovic S, Erdmann D. Silicone Migration and Late Hematoma following Silicone Implant rupture: Case Report and Literature Review. Plast Reconstr Surg Glob Open. 2018;6(8):e1849.CrossRefPubMedPubMedCentral
33.
Oh JH, Song SY, Lew DH, Lee DW. Distant Migration of multiple siliconomas in Lower extremities following breast Implant rupture: Case Report. Plast Reconstr Surg Glob Open. 2016;4(10):e1011.CrossRefPubMedPubMedCentral
Metadata
Title
Vulvar migration of injected polyacrylamide hydrogel following breast augmentation: a case report and literature review
Authors
Junxian Wen
Zhijin Li
Yarong Chi
Bo Chen
Tao Hong
Zhifei Liu
Nanze Yu
Xiaojun Wang
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Women's Health / Issue 1/2024
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/s12905-024-02998-0

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