Top

Published in:

01-09-2010 | Technical innovation

Initial experience of dual-energy lung perfusion CT using a dual-source CT system in children

Author: Hyun Woo Goo

Published in: Pediatric Radiology | Issue 9/2010

Abstract

Initial experience of dual-source dual-energy (DE) lung perfusion CT in children is described. In addition to traditional identification of pulmonary emboli, the assessment of lung perfusion is technically feasible with dual-source DE CT in children with acceptable radiation dose. This article describes how to perform dual-source DE lung perfusion CT in children, including the optimization of intravenous injection method and CT dose parameters. How to produce weighted-average CT images for the assessment of pulmonary emboli and colour-coded perfusion maps for the assessment of regional lung perfusion is also detailed. Lung perfusion status can then be evaluated on perfusion maps by means of either qualitative or quantitative analysis. Potential advantages and disadvantages of this emerging CT technique compared to lung perfusion scintigraphy and cardiac MRI are discussed.

Kritsaneepaiboon S, Lee EY, Zurakowski D et al (2009) MDCT pulmonary angiography evaluation of pulmonary embolism in children. AJR 192:1246–1252CrossRefPubMed

Victoria T, Mong A, Altes T et al (2009) Evaluation of pulmonary embolism in a pediatric population with high clinical suspicion. Pediatr Radiol 39:35–41CrossRefPubMed

Babyn PS, Gahunia HK, Massicotte P (2005) Pulmonary thromboembolism in children. Pediatr Radiol 35:258–274CrossRefPubMed

Remy-Jardin M, Pistolesi M, Goodman LR et al (2007) Management of suspected acute pulmonary embolism in the era of CT angiography: a statement from the Fleischner Society. Radiology 245:315–329CrossRefPubMed

Johnson TR, Krauss B, Sedlmair M et al (2007) Material differentiation by dual energy CT: initial experience. Eur Radiol 17:1510–1517CrossRefPubMed

Thieme SF, Becker CR, Hacker M et al (2008) Dual energy CT for the assessment of lung perfusion—correlation to scintigraphy. Eur J Radiol 68:369–374CrossRefPubMed

Fink C, Johnson TR, Michaely HJ et al (2008) Dual-energy CT angiography of the lung in patients with suspected pulmonary embolism: initial results. Rofo 180:879–883PubMed

Pontana F, Faivre JB, Remy-Jardin M et al (2008) Lung perfusion with dual-energy multidetector-row CT (MDCT): feasibility for the evaluation of acute pulmonary embolism in 117 consecutive patients. Acad Radiol 15:1494–1504CrossRefPubMed

Thieme SF, Johnson TR, Lee C et al (2009) Dual-energy CT for the assessment of contrast material distribution in the pulmonary parenchyma. AJR 193:144–149CrossRefPubMed

10.

Zhang LJ, Yang GF, Zhao YE et al (2009) Detection of pulmonary embolism using dual-energy computed tomography and correlation with cardiovascular measurements: a preliminary study. Acta Radiol 50:892–901CrossRefPubMed

11.

Chae EJ, Seo JB, Jang YM et al (2010) Dual-energy CT for assessment of the severity of acute pulmonary embolism: pulmonary perfusion defect score compared with CT angiographic obstruction score and right ventricular/left ventricular diameter ratio. AJR 194:604–610CrossRefPubMed

12.

Zhang LJ, Zhao YE, Wu SY et al (2009) Pulmonary embolism detection with dual-energy CT: experimental study of dual-source CT in rabbits. Radiology 252:61–70CrossRefPubMed

13.

Yang DH, Goo HW (2008) Pediatric 16-slice CT protocols: radiation dose and image quality. J Korean Radiol Soc 59:333–347

14.

Bryan AC, Bentivoglio LG, Beerel F et al (1964) Factors affecting regional distribution of ventilation and perfusion in the lung. J Appl Physiol 19:395–402PubMed

15.

Reinartz P, Windberger JE, Schaefer W et al (2004) Tomographic imaging in the diagnosis of pulmonary embolism: a comparison between V/Q lung scintigraphy in SPECT technique and multislice spiral CT. J Nucl Med 45:1501–1508PubMed

16.

Goo HW, Yang DH, Park IS et al (2007) Time-resolved three-dimensional contrast-enhanced magnetic resonance angiography in patients who have undergone a Fontan operation or bidirectional cavopulmonary connection: initial experience. J Magn Reson Imaging 25:727–736CrossRefPubMed

17.

Mai VM, Berr SS (1999) MR perfusion imaging of pulmonary parenchyma using pulsed arterial spin labeling techniques: FAIRER and FAIR. J Magn Reson Imaging 9:483–487CrossRefPubMed

18.

Schoepf UJ, Bruening R, Konschitzky H et al (2000) Pulmonary embolism: comprehensive diagnosis by using electron-beam CT for detection of emboli and assessment of pulmonary blood flow. Radiology 217:693–700PubMed

19.

Wildberger JE, Klotz E, Ditt H et al (2005) Multislice computed tomography perfusion imaging for visualization of acute pulmonary embolism: animal experience. Eur Radiol 15:1378–1386CrossRefPubMed

20.

Petersilka M, Bruder H, Krauss B et al (2008) Technical principles of dual source CT. Eur J Radiol 68:362–368CrossRefPubMed

21.

Chae EJ, Seo JB, Goo HW et al (2008) Xenon ventilation CT with a dual-energy technique of dual-source CT: initial experience. Radiology 248:615–624CrossRefPubMed

22.

Goo HW, Chae EJ, Seo JB et al (2008) Xenon ventilation CT using a dual-source dual-energy technique: dynamic ventilation abnormality in a child with bronchial atresia. Pediatr Radiol 38:1113–1116CrossRefPubMed

Title: Initial experience of dual-energy lung perfusion CT using a dual-source CT system in children
Author: Hyun Woo Goo
Publication date: 01-09-2010
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 9/2010
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-010-1759-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Initial experience of dual-energy lung perfusion CT using a dual-source CT system in children

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 9/2010

Biphasic threat to femoral head perfusion in abduction: arterial hypoperfusion and venous congestion

Sonographic assessment of renal size and growth in premature infants

A pictorial review of imaging of abdominal tumours in adolescence

Reply to Wiwanitkit: MRI finding in vaccine-associated paralytic poliomyelitis

Congenital megacalyces

Congenital megacalyces presenting as neonatal hydronephrosis