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Published in: Pediatric Radiology 9/2010

01-09-2010 | Pictorial Essay

A pictorial review of imaging of abdominal tumours in adolescence

Authors: Darshana D. Rasalkar, Winnie C. W. Chu, Frankie W. T. Cheng, Sze Ki Hui, Siu Cheung Ling, Chi Kong Li

Published in: Pediatric Radiology | Issue 9/2010

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Abstract

Neoplastic abdominal tumours, particularly those originating from embryonal tissue (such as hepatoblastoma and nephroblastoma) and neural crest cells (such as neuroblastoma), are well-documented in young children. Neoplasms of adulthood, most commonly carcinoma of different visceral organs, are also well-documented. Abdominal tumours in adolescence constitute a distinct pathological group. The radiological features of some of these tumours have been described only in isolated reports. The purpose of this pictorial essay was to review the imaging findings of various kinds of abdominal tumours in adolescent patients (with an age range of 10–16 years) who presented to the Children Cancer Center of our institution in the past 15 years. Some tumours, though rare, have characteristic imaging appearances (especially in CT) that enable an accurate diagnosis before definite histological confirmation.
Literature
1.
go back to reference Slovis TL (2003) Children, computed tomography radiation dose, and the As Low As Reasonably Achievable (ALARA) concept. Pediatrics 112:971–972CrossRefPubMed Slovis TL (2003) Children, computed tomography radiation dose, and the As Low As Reasonably Achievable (ALARA) concept. Pediatrics 112:971–972CrossRefPubMed
2.
go back to reference Kaste SC (2009) Imaging challenges: a US perspective on controlling exposure to ionizing radiation in children with cancer. Pediatr Radiol 39:S74–S79CrossRefPubMed Kaste SC (2009) Imaging challenges: a US perspective on controlling exposure to ionizing radiation in children with cancer. Pediatr Radiol 39:S74–S79CrossRefPubMed
3.
go back to reference Isaacs HJ (1997) Liver tumours In: Tumours of the fetus and newborn. Saunders, Philadelphia, pp 278–297 Isaacs HJ (1997) Liver tumours In: Tumours of the fetus and newborn. Saunders, Philadelphia, pp 278–297
4.
go back to reference Huguet C, Stipa F, Gavelli A (1994) Primary hepatocellular cancer: Western experience. In: Blumgart LH (ed) Surgery of the liver and biliary tract. Churchill Livingstone, Edinburgh, pp 1365–1369 Huguet C, Stipa F, Gavelli A (1994) Primary hepatocellular cancer: Western experience. In: Blumgart LH (ed) Surgery of the liver and biliary tract. Churchill Livingstone, Edinburgh, pp 1365–1369
5.
go back to reference Bellani FF, Massimino M (1993) Liver tumors in childhood: epidemiology and clinics. J Surg Oncol Suppl 3:119–121CrossRefPubMed Bellani FF, Massimino M (1993) Liver tumors in childhood: epidemiology and clinics. J Surg Oncol Suppl 3:119–121CrossRefPubMed
6.
go back to reference Chen JC, Chen CC, Chen WJ et al (1998) Hepatocellular carcinoma in children: clinical review and comparison with adult cases. J Pediatr Surg 33:1350–1354CrossRefPubMed Chen JC, Chen CC, Chen WJ et al (1998) Hepatocellular carcinoma in children: clinical review and comparison with adult cases. J Pediatr Surg 33:1350–1354CrossRefPubMed
7.
go back to reference Kim T, Murakami T, Oi H et al (1995) Detection of hypervascular hepatocellular carcinoma by dynamic MRI and dynamic spiral CT. J Comput Assist Tomogr 19:948–954CrossRefPubMed Kim T, Murakami T, Oi H et al (1995) Detection of hypervascular hepatocellular carcinoma by dynamic MRI and dynamic spiral CT. J Comput Assist Tomogr 19:948–954CrossRefPubMed
8.
go back to reference Wanless IR, Mawdsley C, Adams R (1985) On the pathogenesis of focal nodular hyperplasia of the liver. Hepatology 5:1194–1200CrossRefPubMed Wanless IR, Mawdsley C, Adams R (1985) On the pathogenesis of focal nodular hyperplasia of the liver. Hepatology 5:1194–1200CrossRefPubMed
9.
go back to reference Shamsi K, De Schepper A, Degryse H et al (1993) Focal nodular hyperplasia of the liver: radiologic findings. Abdom Imaging 18:32–38CrossRefPubMed Shamsi K, De Schepper A, Degryse H et al (1993) Focal nodular hyperplasia of the liver: radiologic findings. Abdom Imaging 18:32–38CrossRefPubMed
10.
go back to reference Wanless IR (1990) Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2, 500 autopsies and a new classification of benign hepatocellular nodules. Hepatology 11:787–797CrossRefPubMed Wanless IR (1990) Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2, 500 autopsies and a new classification of benign hepatocellular nodules. Hepatology 11:787–797CrossRefPubMed
11.
go back to reference Brisse H, Servois V, Bouche B et al (2000) Hepatic regenerating nodules: a mimic of recurrent cancer in children. Pediatr Radiol 30:386–393CrossRefPubMed Brisse H, Servois V, Bouche B et al (2000) Hepatic regenerating nodules: a mimic of recurrent cancer in children. Pediatr Radiol 30:386–393CrossRefPubMed
12.
go back to reference Kirks DR (1998) Practical pediatric imaging. Diagnostic radiology of infants and children, 3rd edn. Lippincott, Williams and Wilkins, Philadelphia Kirks DR (1998) Practical pediatric imaging. Diagnostic radiology of infants and children, 3rd edn. Lippincott, Williams and Wilkins, Philadelphia
13.
go back to reference Murphy WM, Grignon DJ, Perlman EJ (2004) Tumors of the kidney, bladder, and related urinary structures. American Registry of Pathology, Washington, DC Murphy WM, Grignon DJ, Perlman EJ (2004) Tumors of the kidney, bladder, and related urinary structures. American Registry of Pathology, Washington, DC
14.
go back to reference Lowe LH, Isuani BH, Heller RM et al (2000) Pediatric renal masses: Wilms tumor and beyond. Radiographics 20:1585–1603PubMed Lowe LH, Isuani BH, Heller RM et al (2000) Pediatric renal masses: Wilms tumor and beyond. Radiographics 20:1585–1603PubMed
15.
16.
go back to reference Maccioni F, Della Rocca C, Salvi PF et al (2000) Malignant peripheral neuroectodermal tumor (MPNET) of the kidney. Abdom Imaging 25:103–106CrossRefPubMed Maccioni F, Della Rocca C, Salvi PF et al (2000) Malignant peripheral neuroectodermal tumor (MPNET) of the kidney. Abdom Imaging 25:103–106CrossRefPubMed
17.
go back to reference Jurgens H, Bier V, Harms D et al (1988) Malignant peripheral neuroectodermal tumors. A retrospective analysis of 42 patients. Cancer 61:349–357CrossRefPubMed Jurgens H, Bier V, Harms D et al (1988) Malignant peripheral neuroectodermal tumors. A retrospective analysis of 42 patients. Cancer 61:349–357CrossRefPubMed
18.
go back to reference Chu WC, Reznikov B, Lee EY et al (2008) Primitive neuroectodermal tumour (PNET) of the kidney: a rare renal tumour in adolescents with seemingly characteristic radiological features. Pediatr Radiol 38:1089–1094CrossRefPubMed Chu WC, Reznikov B, Lee EY et al (2008) Primitive neuroectodermal tumour (PNET) of the kidney: a rare renal tumour in adolescents with seemingly characteristic radiological features. Pediatr Radiol 38:1089–1094CrossRefPubMed
19.
go back to reference Mor Y, Nass D, Raviv G et al (1994) Malignant peripheral primitive neuroectodermal tumor (PNET) of the kidney. Med Pediatr Oncol 23:437–440CrossRefPubMed Mor Y, Nass D, Raviv G et al (1994) Malignant peripheral primitive neuroectodermal tumor (PNET) of the kidney. Med Pediatr Oncol 23:437–440CrossRefPubMed
20.
go back to reference Cools J, Wlodarska I, Somers R et al (2002) Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor. Genes Chromosom Cancer 34:354–362CrossRefPubMed Cools J, Wlodarska I, Somers R et al (2002) Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor. Genes Chromosom Cancer 34:354–362CrossRefPubMed
21.
go back to reference Schneider G, Ahlhelm F, Altmeyer K et al (2001) Rare pseudotumors of the urinary bladder in childhood. Eur Radiol 11:1024–1029CrossRefPubMed Schneider G, Ahlhelm F, Altmeyer K et al (2001) Rare pseudotumors of the urinary bladder in childhood. Eur Radiol 11:1024–1029CrossRefPubMed
22.
go back to reference Grovas A, Fremgen A, Rauck A et al (1997) The National Cancer Data Base report on patterns of childhood cancers in the United States. Cancer 80:2321–2332CrossRefPubMed Grovas A, Fremgen A, Rauck A et al (1997) The National Cancer Data Base report on patterns of childhood cancers in the United States. Cancer 80:2321–2332CrossRefPubMed
23.
go back to reference Kaufman BH, Telander RL, van Heerden JA et al (1983) Pheochromocytoma in the pediatric age group: current status. J Pediatr Surg 18:879–884CrossRefPubMed Kaufman BH, Telander RL, van Heerden JA et al (1983) Pheochromocytoma in the pediatric age group: current status. J Pediatr Surg 18:879–884CrossRefPubMed
24.
go back to reference Allolio B, Hahner S, Weismann D et al (2004) Management of adrenocortical carcinoma. Clin Endocrinol 60:273–287CrossRef Allolio B, Hahner S, Weismann D et al (2004) Management of adrenocortical carcinoma. Clin Endocrinol 60:273–287CrossRef
25.
go back to reference Dunnick NR, Heaston D, Halvorsen R et al (1982) CT appearance of adrenal cortical carcinoma. J Comput Assist Tomogr 6:978–982CrossRefPubMed Dunnick NR, Heaston D, Halvorsen R et al (1982) CT appearance of adrenal cortical carcinoma. J Comput Assist Tomogr 6:978–982CrossRefPubMed
26.
go back to reference Skinner MA, Schlatter MG, Heifetz SA et al (1993) Ovarian neoplasms in children. Arch Surg 128:849–853, discussion 853–844PubMed Skinner MA, Schlatter MG, Heifetz SA et al (1993) Ovarian neoplasms in children. Arch Surg 128:849–853, discussion 853–844PubMed
27.
go back to reference van Winter JT, Simmons PS, Podratz KC (1994) Surgically treated adnexal masses in infancy, childhood, and adolescence. Am J Obstet Gynecol 170:1780–1786, discussion 1786–1789PubMed van Winter JT, Simmons PS, Podratz KC (1994) Surgically treated adnexal masses in infancy, childhood, and adolescence. Am J Obstet Gynecol 170:1780–1786, discussion 1786–1789PubMed
28.
go back to reference Brown MF, Hebra A, McGeehin K et al (1993) Ovarian masses in children: a review of 91 cases of malignant and benign masses. J Pediatr Surg 28:930–933CrossRefPubMed Brown MF, Hebra A, McGeehin K et al (1993) Ovarian masses in children: a review of 91 cases of malignant and benign masses. J Pediatr Surg 28:930–933CrossRefPubMed
29.
go back to reference Caruso PA, Marsh MR, Minkowitz S et al (1971) An intense clinicopathologic study of 305 teratomas of the ovary. Cancer 27:343–348CrossRefPubMed Caruso PA, Marsh MR, Minkowitz S et al (1971) An intense clinicopathologic study of 305 teratomas of the ovary. Cancer 27:343–348CrossRefPubMed
30.
go back to reference Malkasian GD, Symmonds RE, Dockerty MB (1965) Malignant ovarina teratomas. Report of 31 Cases. Obstet Gynecol 25:810–814PubMed Malkasian GD, Symmonds RE, Dockerty MB (1965) Malignant ovarina teratomas. Report of 31 Cases. Obstet Gynecol 25:810–814PubMed
31.
go back to reference Lim FK, Chanrachakul B, Chong SM et al (1998) Malignant ovarian germ cell tumours: experience in the National University Hospital of Singapore. Ann Acad Med Singapore 27:657–661PubMed Lim FK, Chanrachakul B, Chong SM et al (1998) Malignant ovarian germ cell tumours: experience in the National University Hospital of Singapore. Ann Acad Med Singapore 27:657–661PubMed
32.
go back to reference Kurman RJ, Norris HJ (1976) Embryonal carcinoma of the ovary: a clinicopathologic entity distinct from endodermal sinus tumor resembling embryonal carcinoma of the adult testis. Cancer 38:2420–2433CrossRefPubMed Kurman RJ, Norris HJ (1976) Embryonal carcinoma of the ovary: a clinicopathologic entity distinct from endodermal sinus tumor resembling embryonal carcinoma of the adult testis. Cancer 38:2420–2433CrossRefPubMed
33.
go back to reference Jacobs BC, Wood BP (1993) Radiological case of the month. Malignant ovarian germ cell tumor. Am J Dis Child 147:1007–1008 Jacobs BC, Wood BP (1993) Radiological case of the month. Malignant ovarian germ cell tumor. Am J Dis Child 147:1007–1008
34.
go back to reference Kiratli H, Bilgic S, Gedikoglu G et al (1999) Primitive neuroectodermal tumor of the orbit in an adult. A case report and literature review. Ophthalmology 106:98–102CrossRefPubMed Kiratli H, Bilgic S, Gedikoglu G et al (1999) Primitive neuroectodermal tumor of the orbit in an adult. A case report and literature review. Ophthalmology 106:98–102CrossRefPubMed
35.
go back to reference Berek JS, Hacker NF (eds) (2000) Practical gynecologic oncology. Lippincott Williams & Wilkins, Philadelphia, pp 3–38 Berek JS, Hacker NF (eds) (2000) Practical gynecologic oncology. Lippincott Williams & Wilkins, Philadelphia, pp 3–38
36.
go back to reference Kleinman GM, Young RH, Scully RE (1993) Primary neuroectodermal tumors of the ovary. A report of 25 cases. Am J Surg Pathol 17:764–778CrossRefPubMed Kleinman GM, Young RH, Scully RE (1993) Primary neuroectodermal tumors of the ovary. A report of 25 cases. Am J Surg Pathol 17:764–778CrossRefPubMed
37.
go back to reference Young RH (2005) Sex cord-stromal tumors of the ovary and testis: their similarities and differences with consideration of selected problems. Mod Pathol 18:S81–S98CrossRefPubMed Young RH (2005) Sex cord-stromal tumors of the ovary and testis: their similarities and differences with consideration of selected problems. Mod Pathol 18:S81–S98CrossRefPubMed
38.
go back to reference Stuart GC, Dawson LM (2003) Update on granulosa cell tumours of the ovary. Curr Opin Obstet Gynecol 15:33–37CrossRefPubMed Stuart GC, Dawson LM (2003) Update on granulosa cell tumours of the ovary. Curr Opin Obstet Gynecol 15:33–37CrossRefPubMed
39.
go back to reference Buy JN, Ghossain MA, Moss AA et al (1989) Cystic teratoma of the ovary: CT detection. Radiology 171:697–701PubMed Buy JN, Ghossain MA, Moss AA et al (1989) Cystic teratoma of the ovary: CT detection. Radiology 171:697–701PubMed
40.
go back to reference Vane DW, Grosfeld JL, West KW et al (1989) Pancreatic disorders in infancy and childhood: experience with 92 cases. J Pediatr Surg 24:771–776CrossRefPubMed Vane DW, Grosfeld JL, West KW et al (1989) Pancreatic disorders in infancy and childhood: experience with 92 cases. J Pediatr Surg 24:771–776CrossRefPubMed
41.
go back to reference Procacci C, Graziani R, Bicego E et al (1995) Papillary cystic neoplasm of the pancreas: radiological findings. Abdom Imaging 20:554–558CrossRefPubMed Procacci C, Graziani R, Bicego E et al (1995) Papillary cystic neoplasm of the pancreas: radiological findings. Abdom Imaging 20:554–558CrossRefPubMed
42.
go back to reference Sun CD, Lee WJ, Choi JS et al (2005) Solid-pseudopapillary tumours of the pancreas: 14 years experience. ANZ J Surg 75:684–689CrossRefPubMed Sun CD, Lee WJ, Choi JS et al (2005) Solid-pseudopapillary tumours of the pancreas: 14 years experience. ANZ J Surg 75:684–689CrossRefPubMed
43.
go back to reference Buetow PC, Buck JL, Pantongrag-Brown L et al (1996) Solid and papillary epithelial neoplasm of the pancreas: imaging-pathologic correlation on 56 cases. Radiology 199:707–711PubMed Buetow PC, Buck JL, Pantongrag-Brown L et al (1996) Solid and papillary epithelial neoplasm of the pancreas: imaging-pathologic correlation on 56 cases. Radiology 199:707–711PubMed
44.
go back to reference Balthazar EJ, Subramanyam BR, Lefleur RS et al (1984) Solid and papillary epithelial neoplasm of the pancreas. Radiographic, CT, sonographic, and angiographic features. Radiology 150:39–40PubMed Balthazar EJ, Subramanyam BR, Lefleur RS et al (1984) Solid and papillary epithelial neoplasm of the pancreas. Radiographic, CT, sonographic, and angiographic features. Radiology 150:39–40PubMed
45.
go back to reference Bellah R, Suzuki-Bordalo L, Brecher E et al (2005) Desmoplastic small round cell tumor in the abdomen and pelvis: report of CT findings in 11 affected children and young adults. AJR 184:1910–1914PubMed Bellah R, Suzuki-Bordalo L, Brecher E et al (2005) Desmoplastic small round cell tumor in the abdomen and pelvis: report of CT findings in 11 affected children and young adults. AJR 184:1910–1914PubMed
46.
go back to reference Leuschner I, Radig K, Harms D (1996) Desmoplastic small round cell tumor. Semin Diagn Pathol 13:204–212PubMed Leuschner I, Radig K, Harms D (1996) Desmoplastic small round cell tumor. Semin Diagn Pathol 13:204–212PubMed
47.
go back to reference Kretschmar CS, Colbach C, Bhan I et al (1996) Desmoplastic small cell tumor: a report of three cases and a review of the literature. J Pediatr Hematol Oncol 18:293–298CrossRefPubMed Kretschmar CS, Colbach C, Bhan I et al (1996) Desmoplastic small cell tumor: a report of three cases and a review of the literature. J Pediatr Hematol Oncol 18:293–298CrossRefPubMed
48.
go back to reference Kushner BH, LaQuaglia MP, Wollner N et al (1996) Desmoplastic small round-cell tumor: prolonged progression-free survival with aggressive multimodality therapy. J Clin Oncol 14:1526–1531PubMed Kushner BH, LaQuaglia MP, Wollner N et al (1996) Desmoplastic small round-cell tumor: prolonged progression-free survival with aggressive multimodality therapy. J Clin Oncol 14:1526–1531PubMed
49.
go back to reference Sandlund JT, Downing JR, Crist WM (1996) Non-Hodgkin’s lymphoma in childhood. NEJM 334:1238–1248CrossRefPubMed Sandlund JT, Downing JR, Crist WM (1996) Non-Hodgkin’s lymphoma in childhood. NEJM 334:1238–1248CrossRefPubMed
50.
go back to reference Rasalkar DD, Chu WC, To KF et al (2010) Radiological appearance of inflammatory myofibroblastic tumour. Pediatr Blood Cancer 54:1029–1031PubMed Rasalkar DD, Chu WC, To KF et al (2010) Radiological appearance of inflammatory myofibroblastic tumour. Pediatr Blood Cancer 54:1029–1031PubMed
Metadata
Title
A pictorial review of imaging of abdominal tumours in adolescence
Authors
Darshana D. Rasalkar
Winnie C. W. Chu
Frankie W. T. Cheng
Sze Ki Hui
Siu Cheung Ling
Chi Kong Li
Publication date
01-09-2010
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 9/2010
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-010-1738-z

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