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Published in: BMC Infectious Diseases 1/2016

Open Access 01-12-2016 | Research article

Influenza in long-term Dutch travelers in the tropics: symptoms and infections

Authors: Jane Whelan, Guus F. Rimmelzwaan, Anneke van den Hoek, Sanne-Meike Belderok, Gerard J. B. Sonder

Published in: BMC Infectious Diseases | Issue 1/2016

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Abstract

Background

Influenza is a common infection among travelers, and attack rates are well documented in short-term travelers and holiday makers. Little data exists on long-term, non-expatriate travelers.

Methods

This was a prospective mono-centre study of immunocompetent, Dutch travelers aged ≥18 to 64 years. It was conducted at the Public Health Service travel clinic in Amsterdam from December 2008 to September 2011, and included all travelers intending to travel to a tropical or sub-tropical country.

Results

Among 602 Dutch long-term travelers to tropical regions, 82 % had protective influenza antibody titres pre-travel. The influenza attack rate of serologically confirmed infection during travel was 15 %, and of symptomatic infection was 6.3 % (fever alone) and 2 % (ILI), respectively.

Conclusions

The attack rate in this study is similar to seasonal rates of infection in the general population. Influenza vaccination pre-travel is therefore most important for people at risk of medical complications due to influenza.
Literature
1.
go back to reference Mutsch M, Tavernini M, Marx A, et al. Influenza virus infection in travelers to tropical and subtropical countries. Clin Infect Dis Off Publication Infect Dis Soc Am. 2005;40(9):1282–7.CrossRef Mutsch M, Tavernini M, Marx A, et al. Influenza virus infection in travelers to tropical and subtropical countries. Clin Infect Dis Off Publication Infect Dis Soc Am. 2005;40(9):1282–7.CrossRef
2.
go back to reference Odolini S, Parola P, Gkrania-Klotsas E, Caumes E, Schlagenhauf P, Lopez-Velez R, et al. Travel-related imported infections in europe, EuroTravNet 2009. Clinical microbiology and infection: the official publication of the european society of clinical microbiology and infectious diseases. Clin Microbiol Infect. 2012;18(5):468–74.CrossRefPubMed Odolini S, Parola P, Gkrania-Klotsas E, Caumes E, Schlagenhauf P, Lopez-Velez R, et al. Travel-related imported infections in europe, EuroTravNet 2009. Clinical microbiology and infection: the official publication of the european society of clinical microbiology and infectious diseases. Clin Microbiol Infect. 2012;18(5):468–74.CrossRefPubMed
3.
go back to reference Reid D, Dewar RD, Fallon RJ, Cossar JH, Grist NR. Infection and travel: the experience of package tourists and other travellers. J Infect. 1980;2(4):365–70.CrossRefPubMed Reid D, Dewar RD, Fallon RJ, Cossar JH, Grist NR. Infection and travel: the experience of package tourists and other travellers. J Infect. 1980;2(4):365–70.CrossRefPubMed
4.
5.
go back to reference Miller JM, Tam TW, Maloney S, et al. Cruise ships: high-risk passengers and the global spread of new influenza viruses. Clin Infect Dis Off Publication Infect Dis Soc Am. 2000;31(2):433–8.CrossRef Miller JM, Tam TW, Maloney S, et al. Cruise ships: high-risk passengers and the global spread of new influenza viruses. Clin Infect Dis Off Publication Infect Dis Soc Am. 2000;31(2):433–8.CrossRef
6.
go back to reference Davis XM, Hay KA, Plier DA, et al. International travelers as sentinels for sustained influenza transmission during the 2009 influenza A(H1N1)pdm09 pandemic. J Travel Med. 2013;20(3):177–84.CrossRefPubMed Davis XM, Hay KA, Plier DA, et al. International travelers as sentinels for sustained influenza transmission during the 2009 influenza A(H1N1)pdm09 pandemic. J Travel Med. 2013;20(3):177–84.CrossRefPubMed
7.
go back to reference Palmer D, Dowdle W, Coleman M, Schild G. Hemagglutination in hibition test. Advance laboratory techniques for influenza diagnosis. Procedural guide. Atlanta: US Department of Health, Education, and Welfare; 1975. p. 25–62. Palmer D, Dowdle W, Coleman M, Schild G. Hemagglutination in hibition test. Advance laboratory techniques for influenza diagnosis. Procedural guide. Atlanta: US Department of Health, Education, and Welfare; 1975. p. 25–62.
8.
go back to reference Masurel N, Ophof P, de Jong P. Antibody response to immunization with influenza A/USSR/77 (H1N1) virus in young individuals primed or unprimed for A/New Jersey/76 (H1N1) virus. J Hyg (Lond). 1981;87(2):201–9.CrossRef Masurel N, Ophof P, de Jong P. Antibody response to immunization with influenza A/USSR/77 (H1N1) virus in young individuals primed or unprimed for A/New Jersey/76 (H1N1) virus. J Hyg (Lond). 1981;87(2):201–9.CrossRef
11.
go back to reference Novel Swine Origin Influenza A(H1N1) Virus Investigation Team, Dawood FS, Jain S, et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med. 2009;360(25):2605–15.CrossRef Novel Swine Origin Influenza A(H1N1) Virus Investigation Team, Dawood FS, Jain S, et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med. 2009;360(25):2605–15.CrossRef
13.
go back to reference Ratnam I, Black J, Leder K, et al. Incidence and risk factors for acute respiratory illnesses and influenza virus infections in Australian travellers to Asia. J Clin Virol. 2013;57(1):54–8.CrossRefPubMed Ratnam I, Black J, Leder K, et al. Incidence and risk factors for acute respiratory illnesses and influenza virus infections in Australian travellers to Asia. J Clin Virol. 2013;57(1):54–8.CrossRefPubMed
14.
go back to reference Hayward AC, Fragaszy EB, Bermingham A, et al. Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study. Lancet Respir Med. 2014;2(6):445–54.CrossRefPubMed Hayward AC, Fragaszy EB, Bermingham A, et al. Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study. Lancet Respir Med. 2014;2(6):445–54.CrossRefPubMed
15.
go back to reference Horby P, le Mai Q, Fox A, et al. The epidemiology of interpandemic and pandemic influenza in Vietnam, 2007–2010: the Ha Nam household cohort study I. Am J Epidemiol. 2012;175(10):1062–74.CrossRefPubMedPubMedCentral Horby P, le Mai Q, Fox A, et al. The epidemiology of interpandemic and pandemic influenza in Vietnam, 2007–2010: the Ha Nam household cohort study I. Am J Epidemiol. 2012;175(10):1062–74.CrossRefPubMedPubMedCentral
16.
go back to reference Freedman DO, Leder K. Influenza: changing approaches to prevention and treatment in travelers. J Travel Med. 2005;12:36–44.CrossRefPubMed Freedman DO, Leder K. Influenza: changing approaches to prevention and treatment in travelers. J Travel Med. 2005;12:36–44.CrossRefPubMed
Metadata
Title
Influenza in long-term Dutch travelers in the tropics: symptoms and infections
Authors
Jane Whelan
Guus F. Rimmelzwaan
Anneke van den Hoek
Sanne-Meike Belderok
Gerard J. B. Sonder
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2016
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-016-1502-6

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