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Inflammation
Published in: Inflammation 2/2012

Open Access 01-04-2012

Inflammatory Markers: Exhaled Nitric Oxide and Carbon Monoxide During the Ovarian Cycle

Authors: Adam Antczak, Maciej Ciebiada, Sergei A. Kharitonov, Pawel Gorski, Peter J. Barnes

Published in: Inflammation | Issue 2/2012

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Abstract

Nitric oxide (NO) production and carbon monoxide (CO) production are increased in inflammatory lung diseases. Although there are some pieces of evidence for hormonal modulation by estrogen, little is known about exhaled NO and CO during the ovarian cycle. In 23 subjects, we measured exhaled NO and CO by an online analyzer. Significantly higher levels of exhaled NO were found at the midcycle compared with those in the premenstrual period or during menstruation. Higher levels of CO were after ovulation and reached a peak in the premenstrual phase. The lowest levels of CO were observed in the first days of the estrogen phase. In males, there was no significant variation in exhaled NO and CO. Exhaled NO and CO levels vary during the ovarian cycle in women, and this fact should be taken into account during serial measurements of these markers in the female population.
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Metadata
Title
Inflammatory Markers: Exhaled Nitric Oxide and Carbon Monoxide During the Ovarian Cycle
Authors
Adam Antczak
Maciej Ciebiada
Sergei A. Kharitonov
Pawel Gorski
Peter J. Barnes
Publication date
01-04-2012
Publisher
Springer US
Published in
Inflammation / Issue 2/2012
Print ISSN: 0360-3997
Electronic ISSN: 1573-2576
DOI
https://doi.org/10.1007/s10753-011-9345-1

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