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Published in: Current Hypertension Reports 1/2015

01-01-2015 | Antihypertensive Agents: Mechanisms of Drug Action (M Ernst, Section Editor)

Inflammation and Hypertension: New Understandings and Potential Therapeutic Targets

Authors: Carmen De Miguel, Nathan P. Rudemiller, Justine M. Abais, David L. Mattson

Published in: Current Hypertension Reports | Issue 1/2015

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Abstract

Research studying the role of inflammation in hypertension and cardiovascular disease has flourished in recent years; however, the exact mechanisms by which the activated immune cells lead to the development and maintenance of hypertension remain to be elucidated. The objectives of this brief review are to summarize and discuss the most recent findings in the field, with special emphasis on potential therapeutics to treat or prevent hypertension. This review will cover novel immune cell subtypes recently associated to the disease including the novel role of cytokines, toll-like receptors, and inflammasomes in hypertension.
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Metadata
Title
Inflammation and Hypertension: New Understandings and Potential Therapeutic Targets
Authors
Carmen De Miguel
Nathan P. Rudemiller
Justine M. Abais
David L. Mattson
Publication date
01-01-2015
Publisher
Springer US
Published in
Current Hypertension Reports / Issue 1/2015
Print ISSN: 1522-6417
Electronic ISSN: 1534-3111
DOI
https://doi.org/10.1007/s11906-014-0507-z

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