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Autoimmunity Highlights
Published in: Autoimmunity Highlights 1/2016

Open Access 01-12-2016 | Review Article

Infections as a cause of autoimmune rheumatic diseases

Authors: Lazaros I. Sakkas, Dimitrios P. Bogdanos

Published in: Autoimmunity Highlights | Issue 1/2016

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Abstract

Exogenous and endogenous environmental exposures and particularly infections may participate in the breakage of tolerance and the induction of autoimmunity in rheumatic diseases. Response to infections apparently occurs years before clinical manifestations and features of autoimmunity, such as autoantibodies, are detected years before clinical manifestations in autoimmune rheumatic diseases. In this review, we summarize the current evidence for a potential causal link between infectious agents and rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, Sjogren’s syndrome and ANCA-associated vasculitis.
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Metadata
Title
Infections as a cause of autoimmune rheumatic diseases
Authors
Lazaros I. Sakkas
Dimitrios P. Bogdanos
Publication date
01-12-2016
Publisher
Springer International Publishing
Published in
Autoimmunity Highlights / Issue 1/2016
Print ISSN: 2038-0305
Electronic ISSN: 2038-3274
DOI
https://doi.org/10.1007/s13317-016-0086-x

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