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BMC Pediatrics

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Open Access 01-12-2024 | Infantile Hemangioma | Research

Clinical characteristics of infantile haemangioma in twins: a retrospective study

Authors: Zhengwei Sun, Miaomiao Li, Changxian Dong, Shiwei Mei

Published in: BMC Pediatrics | Issue 1/2024

Abstract

Background

Infantile hemangioma is one of the most common benign soft tissue tumors in infants. The pathogenesis of infantile hemangioma remains unclear and twin studies regarding its incidence may help clarify disease pathogenesis. Thus, this study aimed to analyze the clinical characteristics of infantile hemangioma in twin patients and discuss its clinical incidence.

Methods

We retrospectively analyzed the data of 83 pairs of twins with infantile hemangioma admitted to the Guangdong Provincial Women and Children Hospital and Henan Provincial People’s Hospital between May 2016 and May 2022. Thirty-one pairs of twins among whom both developed infantile hemangioma and 52 pairs of twins among whom only one twin was affected were included. Analysis was performed using the Spearman correlation. Additionally, we analyzed the influence of factors such as sex, twin zygosity, preterm birth, birth weight, and assisted reproduction on the clinical characteristics of twins.

Results

We observed that disease occurrence in both twins correlated with assisted reproduction (χ2 = 13. 102, P < 0.05) and preterm birth (χ2 = 36.523, P < 0.05). Twin zygosity (χ2 = 0.716, P > 0.05) and total birth weight of twins (t=-3.369, P > 0.05) were not correlated with infantile hemangioma. However, among twins, the ones with lesser birth weight were more likely to develop infantile hemangioma.

Conclusions

The clinical characteristics of infantile hemangioma in twins were consistent with their epidemiological characteristics. Female sex, preterm birth, less birth weight, and assisted reproduction increased the probability of morbidity in both twins. Analysis of the characteristics of infantile hemangioma in twins may assist further research and clinical treatment.

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Title: Clinical characteristics of infantile haemangioma in twins: a retrospective study
Authors: Zhengwei Sun
Miaomiao Li
Changxian Dong
Shiwei Mei
Publication date: 01-12-2024
Publisher: BioMed Central
Keywords: Infantile Hemangioma
Infantile Hemangioma
Assisted Reproduction
Premature Birth
Hemangioma
Hemangioma
Hemangioma
Hemangioma
Hemangioma
Published in: BMC Pediatrics / Issue 1/2024
Electronic ISSN: 1471-2431
DOI: https://doi.org/10.1186/s12887-024-04602-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical characteristics of infantile haemangioma in twins: a retrospective study

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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