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Published in: Journal of Gastrointestinal Cancer 3/2019

01-09-2019 | Case Report

Indolent Nodal Relapse of Colon Carcinoma with Associated Tumor Thrombus Invading the Superior Mesenteric Vein

Authors: Megan Greally, Keith Pilson, Anna Linehan, Conor O’Keane, Conor J. Shields, John B. Conneely, John A. McCaffrey

Published in: Journal of Gastrointestinal Cancer | Issue 3/2019

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Excerpt

Approximately 50–60% of patients with colorectal cancer develop metastatic disease, with the liver, lungs, and peritoneum being the commonest sites of occurrence. While there is data supporting the role of metastatectomy for liver disease, especially when occurring metachronously, evidence is limited for resection of extrahepatic disease. However, there is some evidence that judicious use of salvage surgery has a role in well-selected patients. This case highlights the extremely rare diagnosis of superior mesenteric vein (SMV) tumor thrombus related to metastatic nodal recurrence of colon cancer in a 54-year-old male with a history of T3N2b colon cancer. We present the diagnostic and management issues associated with this complex case which demonstrated an unusual pattern of recurrence. …
Literature
2.
go back to reference Edge S, Byrd DR, Compton CC, Fritz AG, Greene F, Trotti A. AJCC (American Joint Committee on Cancer) cancer staging manual. 7th ed. New York: Springer; 2010. Edge S, Byrd DR, Compton CC, Fritz AG, Greene F, Trotti A. AJCC (American Joint Committee on Cancer) cancer staging manual. 7th ed. New York: Springer; 2010.
3.
go back to reference Booth CM, Nanji S, Wei X, Peng Y, Biagi JJ, Hanna TP, et al. Use and effectiveness of adjuvant chemotherapy for stage III colon cancer: a population-based study. J Nat Comp Cancer Net: JNCCN. 2016;14(1):47–56.CrossRef Booth CM, Nanji S, Wei X, Peng Y, Biagi JJ, Hanna TP, et al. Use and effectiveness of adjuvant chemotherapy for stage III colon cancer: a population-based study. J Nat Comp Cancer Net: JNCCN. 2016;14(1):47–56.CrossRef
4.
10.
go back to reference Pita-Fernandez S, Alhayek-Ai M, Gonzalez-Martin C, Lopez-Calvino B, Seoane-Pillado T, Pertega-Diaz S. Intensive follow-up strategies improve outcomes in nonmetastatic colorectal cancer patients after curative surgery: a systematic review and meta-analysis. Ann Oncol: Off J Eur Soc Med Oncol. 2015;26(4):644–56. https://doi.org/10.1093/annonc/mdu543.CrossRef Pita-Fernandez S, Alhayek-Ai M, Gonzalez-Martin C, Lopez-Calvino B, Seoane-Pillado T, Pertega-Diaz S. Intensive follow-up strategies improve outcomes in nonmetastatic colorectal cancer patients after curative surgery: a systematic review and meta-analysis. Ann Oncol: Off J Eur Soc Med Oncol. 2015;26(4):644–56. https://​doi.​org/​10.​1093/​annonc/​mdu543.CrossRef
12.
go back to reference Goldberg RM, Fleming TR, Tangen CM, Moertel CG, Macdonald JS, Haller DG, et al. Surgery for recurrent colon cancer: strategies for identifying resectable recurrence and success rates after resection. Eastern Cooperative Oncology Group, the North Central Cancer Treatment Group, and the Southwest Oncology Group. Ann Intern Med. 1998;129(1):27–35.CrossRefPubMed Goldberg RM, Fleming TR, Tangen CM, Moertel CG, Macdonald JS, Haller DG, et al. Surgery for recurrent colon cancer: strategies for identifying resectable recurrence and success rates after resection. Eastern Cooperative Oncology Group, the North Central Cancer Treatment Group, and the Southwest Oncology Group. Ann Intern Med. 1998;129(1):27–35.CrossRefPubMed
14.
go back to reference Kaida H, Ishibashi M, Kurata S, Uchida M, Hayabuchi N. Tumor thrombus in the inferior vena cava from colon cancer detected by 18F-FDG-PET. Ann Nucl Med. 2007;21(3):185–8.CrossRefPubMed Kaida H, Ishibashi M, Kurata S, Uchida M, Hayabuchi N. Tumor thrombus in the inferior vena cava from colon cancer detected by 18F-FDG-PET. Ann Nucl Med. 2007;21(3):185–8.CrossRefPubMed
15.
go back to reference Matsumura A, Hatakeyama T, Ogino S, Takemura M, Mugitani T, Akami T, et al. Two cases of colorectal cancer with tumor thrombus in the inferior mesenteric vein. Gan to kagaku ryoho Cancer Chemother. 2015;42(12):2224–6. Matsumura A, Hatakeyama T, Ogino S, Takemura M, Mugitani T, Akami T, et al. Two cases of colorectal cancer with tumor thrombus in the inferior mesenteric vein. Gan to kagaku ryoho Cancer Chemother. 2015;42(12):2224–6.
17.
go back to reference Izumi R, Shimizu K, Ii T, Yagi M, Matsui O, Nonomura A, et al. Prognostic factors of hepatocellular carcinoma in patients undergoing hepatic resection. Gastroenterology. 1994;106(3):720–7.CrossRef Izumi R, Shimizu K, Ii T, Yagi M, Matsui O, Nonomura A, et al. Prognostic factors of hepatocellular carcinoma in patients undergoing hepatic resection. Gastroenterology. 1994;106(3):720–7.CrossRef
21.
go back to reference Gupta P, Kramer EL, Ponzo F. FDG uptake in tumor thrombus in inferior vena cava from rectal cancer on positron emission tomography. Clin Nucl Med. 2005;30(5):342–3.CrossRefPubMed Gupta P, Kramer EL, Ponzo F. FDG uptake in tumor thrombus in inferior vena cava from rectal cancer on positron emission tomography. Clin Nucl Med. 2005;30(5):342–3.CrossRefPubMed
22.
go back to reference Davidson T, Goitein O, Avigdor A, Zwas ST, Goshen E. 18F- FDG-PET/CT for the diagnosis of tumor thrombosis. Israel Med Assoc J: IMAJ. 2009;11(2):69–73. Davidson T, Goitein O, Avigdor A, Zwas ST, Goshen E. 18F- FDG-PET/CT for the diagnosis of tumor thrombosis. Israel Med Assoc J: IMAJ. 2009;11(2):69–73.
25.
go back to reference Nissan A, Guillem JG, Paty PB, Wong WD, Cohen AM. Signet-ring cell carcinoma of the colon and rectum: a matched control study. Dis Colon rectum. 1999;42(9):1176–80.CrossRefPubMed Nissan A, Guillem JG, Paty PB, Wong WD, Cohen AM. Signet-ring cell carcinoma of the colon and rectum: a matched control study. Dis Colon rectum. 1999;42(9):1176–80.CrossRefPubMed
26.
go back to reference Psathakis D, Schiedeck TH, Krug F, Oevermann E, Kujath P, Bruch HP. Ordinary colorectal adenocarcinoma vs. primary colorectal signet-ring cell carcinoma: study matched for age, gender, grade, and stage. Dis Colon rectum. 1999;42(12):1618–25.CrossRefPubMed Psathakis D, Schiedeck TH, Krug F, Oevermann E, Kujath P, Bruch HP. Ordinary colorectal adenocarcinoma vs. primary colorectal signet-ring cell carcinoma: study matched for age, gender, grade, and stage. Dis Colon rectum. 1999;42(12):1618–25.CrossRefPubMed
27.
go back to reference Bismuth H, Adam R, Levi F, Farabos C, Waechter F, Castaing D, et al. Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy. Ann Surg. 1996;224(4):509–20. discussion 520-502CrossRefPubMedPubMedCentral Bismuth H, Adam R, Levi F, Farabos C, Waechter F, Castaing D, et al. Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy. Ann Surg. 1996;224(4):509–20. discussion 520-502CrossRefPubMedPubMedCentral
28.
go back to reference Fernandez FG, Drebin JA, Linehan DC, Dehdashti F, Siegel BA, Strasberg SM. Five-year survival after resection of hepatic metastases from colorectal cancer in patients screened by positron emission tomography with F-18 fluorodeoxyglucose (FDG-PET). Ann Surg. 2004;240(3):438–447; discussion 447-450.CrossRefPubMedPubMedCentral Fernandez FG, Drebin JA, Linehan DC, Dehdashti F, Siegel BA, Strasberg SM. Five-year survival after resection of hepatic metastases from colorectal cancer in patients screened by positron emission tomography with F-18 fluorodeoxyglucose (FDG-PET). Ann Surg. 2004;240(3):438–447; discussion 447-450.CrossRefPubMedPubMedCentral
30.
go back to reference Shibata D, Paty PB, Guillem JG, Wong WD, Cohen AM. Surgical management of isolated retroperitoneal recurrences of colorectal carcinoma. Dis Colon rectum. 2002;45(6):795–801.CrossRefPubMed Shibata D, Paty PB, Guillem JG, Wong WD, Cohen AM. Surgical management of isolated retroperitoneal recurrences of colorectal carcinoma. Dis Colon rectum. 2002;45(6):795–801.CrossRefPubMed
34.
go back to reference Takeshima K, Yamafuji K, Asami A, Baba H, Okamoto N, Takahashi H, et al. Successful resection of isolated para-aortic lymph node recurrence from advanced sigmoid colon cancer following 156 courses of FOLFIRI regimen. Case Rep Surger. 2016;2016(4548798):1–5. https://doi.org/10.1155/2016/4548798.CrossRef Takeshima K, Yamafuji K, Asami A, Baba H, Okamoto N, Takahashi H, et al. Successful resection of isolated para-aortic lymph node recurrence from advanced sigmoid colon cancer following 156 courses of FOLFIRI regimen. Case Rep Surger. 2016;2016(4548798):1–5. https://​doi.​org/​10.​1155/​2016/​4548798.CrossRef
35.
36.
go back to reference Ychou M, Hohenberger W, Thezenas S, Navarro M, Maurel J, Bokemeyer C, et al. A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer. Ann Oncol: Off J Eur Soc Med Oncol. 2009;20(12):1964–70. https://doi.org/10.1093/annonc/mdp236.CrossRef Ychou M, Hohenberger W, Thezenas S, Navarro M, Maurel J, Bokemeyer C, et al. A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer. Ann Oncol: Off J Eur Soc Med Oncol. 2009;20(12):1964–70. https://​doi.​org/​10.​1093/​annonc/​mdp236.CrossRef
Metadata
Title
Indolent Nodal Relapse of Colon Carcinoma with Associated Tumor Thrombus Invading the Superior Mesenteric Vein
Authors
Megan Greally
Keith Pilson
Anna Linehan
Conor O’Keane
Conor J. Shields
John B. Conneely
John A. McCaffrey
Publication date
01-09-2019
Publisher
Springer US
Published in
Journal of Gastrointestinal Cancer / Issue 3/2019
Print ISSN: 1941-6628
Electronic ISSN: 1941-6636
DOI
https://doi.org/10.1007/s12029-018-0101-8

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