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European Archives of Oto-Rhino-Laryngology
Published in: European Archives of Oto-Rhino-Laryngology 3/2017

Open Access 01-03-2017 | Rhinology

Incidence of IP and risk of malignant transformation in the Swedish population 1960–2010

Authors: Alexandra Elliot, Linda Marklund, Niclas Håkansson, Huan Song, Weimin Ye, Pär Stjärne, Lalle Hammarstedt-Nordenvall

Published in: European Archives of Oto-Rhino-Laryngology | Issue 3/2017

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Abstract

The true incidence of inverted papilloma (IP) is not yet known. From hospital-based studies, its incidence has been estimated to approximately 0.5/100,000 person years. Earlier hospital case studies have shown that IP can undergo a malignant transformation in 1–53 %. The frequency of its malignant transformation on a population basis is unknown. To our knowledge, no standardised incidence ratio (SIR) has been reported for malignancies among IPs. This study aims to investigate these incidences on a population basis. Using the data from the Swedish Cancer Registry (SCR), we have identified patients with IP and patients with Squamous Cell Carcinoma (SCC) diagnosed between 1960 and 2010 in Sweden. Incidence of IP and incidence of SCC among patients with IP and SIR were analyzed. Eight hundred and fourteen patients with IP were identified. The incidence of IPs reported to the SCR increased from 1960 to 2010. In this cohort, SCC was overrepresented, as compared with the general population. The incidence of IP in the Swedish population seems to have increased.
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Metadata
Title
Incidence of IP and risk of malignant transformation in the Swedish population 1960–2010
Authors
Alexandra Elliot
Linda Marklund
Niclas Håkansson
Huan Song
Weimin Ye
Pär Stjärne
Lalle Hammarstedt-Nordenvall
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 3/2017
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-016-4321-x

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