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01-07-2018 | Head and Neck

In vivo imaging of saccular hydrops in humans reflects sensorineural hearing loss rather than Meniere’s disease symptoms

Authors: Arnaud Attyé, Michael Eliezer, Maud Medici, Irène Tropres, Georges Dumas, Alexandre Krainik, Sébastien Schmerber

Published in: European Radiology | Issue 7/2018

Abstract

Objectives

A case-controlled imaging study demonstrated that saccular hydrops was specific to Meniere’s disease (MD), but only present in a subset of patients. Here, we compared patients with definite MD, vertigo and sensorineural hearing loss (SNHL) to elucidate the relationship between saccular hydrops and extent of SNHL.

Methods

In this prospective study, we performed 3D-FLAIR sequences between 4.5 and 5.5 h after contrast media injection in patients with MD (n=20), SNHL (n=20), vertigo (n=20) and 30 healthy subjects. Two radiologists independently graded saccular hydrops. ROC analysis was performed to determine the hearing loss threshold to differentiate patients with saccular hydrops.

Results

Saccular hydrops was found in 11 of 20 MD patients, 10 of 20 SNHL patients and in none of the vertigo patients and healthy subjects. In SNHL patients, 45 dB was the threshold above which there was a significant association with saccular hydrops, with sensitivity of 100 % and specificity of 90 %. In MD patients, 40 dB was the threshold above which there was a significant association with saccular hydrops, with sensitivity of 100 % and specificity of 44 %.

Conclusions

Our results indicate saccular hydrops as a feature of worse than moderate SNHL rather than MD itself.

Key Points

• MRI helps clinicians to assess patients with isolated low-tone sensorineural hearing loss.

• Saccular hydrops correlates with sensorineural hearing loss at levels above 40 dB.

• Vertigo patients without sensorineural hearing loss do not have saccular hydrops.

• Saccular hydrops is described in patients without clinical diagnosis of Meniere’s disease.

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Title: In vivo imaging of saccular hydrops in humans reflects sensorineural hearing loss rather than Meniere’s disease symptoms
Authors: Arnaud Attyé
Michael Eliezer
Maud Medici
Irène Tropres
Georges Dumas
Alexandre Krainik
Sébastien Schmerber
Publication date: 01-07-2018
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 7/2018
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-017-5260-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

In vivo imaging of saccular hydrops in humans reflects sensorineural hearing loss rather than Meniere’s disease symptoms

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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