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Journal of Translational Medicine
Published in: Journal of Translational Medicine 1/2010

Open Access 01-12-2010 | Research

In vivo evidence of htid suppressive activity on ErbB-2 in breast cancers over expressing the receptor

Authors: Ursula Kurzik-Dumke, Manuela Hörner, Maria R Nicotra, Michael Koslowski, Pier G Natali

Published in: Journal of Translational Medicine | Issue 1/2010

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Excerpt

Htid encoded proteins are physiological partners of a wide spectrum of molecules relevant to neoplastic transformation. One of the molecular ligands of the cytosolic hTid-L and hTid-I forms is the ErbB-2 receptor variably over expressed in diverse solid tumors. Altered ErbB-2 signalling is associated with an unfavourable prognosis in about 30% of human breast malignancies. …
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Metadata
Title
In vivo evidence of htid suppressive activity on ErbB-2 in breast cancers over expressing the receptor
Authors
Ursula Kurzik-Dumke
Manuela Hörner
Maria R Nicotra
Michael Koslowski
Pier G Natali
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue 1/2010
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/1479-5876-8-58

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Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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Developed by: Springer Medicine
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