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Published in: Abdominal Radiology 5/2017

01-05-2017

Impact of low-energy CT imaging on selection of positive oral contrast media concentration

Authors: Manuel Patino, Diana J. Murcia, Andrea Prochowski Iamurri, Avinash R. Kambadakone, Peter F. Hahn, Dushyant V. Sahani

Published in: Abdominal Radiology | Issue 5/2017

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Abstract

Objectives

To determine to what extent low-energy CT imaging affects attenuation of gastrointestinal tract (GIT) opacified with positive oral contrast media (OCM). Second, to establish optimal OCM concentrations for low-energy diagnostic CT exams.

Methods

One hundred patients (38 men and 62 women; age 62 ± 11 years; BMI 26 ± 5) with positive OCM-enhanced 120-kVp single-energy CT (SECT), and follow-up 100-kVp acquisitions (group A; n = 50), or 40–70-keV reconstructions from rapid kV switching-single-source dual-energy CT (ssDECT) (group B; n = 50) were included. Luminal attenuation from different GIT segments was compared between exams. Standard dose of three OCM and diluted solutions (75%, 50%, and 25% concentrations) were introduced serially in a gastrointestinal phantom and scanned using SECT (120, 100, and 80 kVp) and DECT (80/140 kVp) acquisitions on a ssDECT scanner. Luminal attenuation was obtained on SECT and DECT images (40–70 keV), and compared to 120-kVp scans with standard OCM concentrations.

Results

Luminal attenuation was higher on 100-kVp (328 HU) and on 40–60-keV images (410–924 HU) in comparison to 120-kVp scans (298 HU) in groups A and B (p < 0.05). Phantom: There was an inverse correlation between luminal attenuation and X-ray energy, increasing up to 527 HU on low-kVp and 999 HU on low-keV images (p < 0.05). 25% and 50% diluted OCM solutions provided similar or higher attenuation than 120 kVp, at low kVp and keV, respectively.

Conclusions

Low-energy CT imaging increases the attenuation of GIT opacified with positive OCM, permitting reduction of 25%–75% OCM concentration.
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Metadata
Title
Impact of low-energy CT imaging on selection of positive oral contrast media concentration
Authors
Manuel Patino
Diana J. Murcia
Andrea Prochowski Iamurri
Avinash R. Kambadakone
Peter F. Hahn
Dushyant V. Sahani
Publication date
01-05-2017
Publisher
Springer US
Published in
Abdominal Radiology / Issue 5/2017
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-016-0993-3

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