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01-04-2012 | Pictorial Essay

Imaging of neonatal brain emergencies: multisequence MRI analysis of pathologic spectrum including diffusion and MR spectroscopy

Authors: Asha Ittoop, T. Thomas Zacharia

Published in: Emergency Radiology | Issue 2/2012

Abstract

The purpose of this pictorial essay is to review the normal neonatal brain MR anatomy and the MR imaging appearances of neonatal brain emergencies and discuss the advantages of individual MR imaging sequences and the clinical implications of utilizing MRI as a problem-solving modality in the neonatal intensive care unit. Here we briefly discuss the normal MR imaging anatomy and myelination pattern and normal MR spectroscopy findings in a neonate. The role of individual MR imaging sequences in evaluating various neonatal abnormalities is being emphasized. For example, the utility of diffusion-weighted imaging for the diagnosis of profound hypoxic–ischemic injury and other forms of hypoxic–ischemic encephalopathies and MR spectroscopy in the diagnosis of metabolic encephalopathies and genetic disorders including aminoacidurias is being presented.

Sie LT, van der Knaap MS, van Wezel-Meijler G et al (2000) Early MR features of hypoxic-ischemic brain injury in neonates with periventricular densities on sonograms. AJNR Am J Neuroradiol 21(5):852–861PubMed

Eken P, Jansen GH, Groenendaal F, Rademaker KJ, De Vries LS (1994) Intracranial lesions in the full term infant with hypoxic ischemic encephalopathy: ultrasound and autopsy correlation. Neuropediatrics 25:301–307PubMedCrossRef

Barkovich AJ (ed) (2005) Normal development of neonatal and infant brain, skull, and spine. In: Pediatric neuroimaging. Lippincott Williams & Wilkins, Philadelphia. p. 57

Evans AC (2006) The NIH MRI study of normal brain development. Neuroimage 30:184–202PubMedCrossRef

Bartha AI, Yap KR, Miller SP et al (2007) The normal neonatal brain: MR imaging, diffusion tensor imaging, and 3D MR spectroscopy in healthy term neonates. AJNR Am J Neuroradiol 28(6):1015–1021PubMedCrossRef

Liauw L, Palm-Meinders IH, van der Grond J et al (2007) Differentiating normal myelination from hypoxic-ischemic encephalopathy on T1-weighted MR images: a new approach. AJNR Am J Neuroradiol 28(4):660–665PubMed

Huang BY, Castillo M (2008) Hypoxic-ischemic brain Injury: imaging findings from birth to adulthood. Radiographics 28(2):417–439PubMedCrossRef

Counsell SJ, Rutherford MA, Cowan FM et al (2003) Magnetic resonance imaging of preterm brain injury. Arch Dis Child Fetal Neonatal Ed 88(4):269–274CrossRef

Miller SP, Cozzio CC, Goldstein RB et al (2003) Comparing the diagnosis of white matter injury in premature newborns with serial MR imaging and transfontanel ultrasonography findings. AJNR Am J Neuroradiol 24(8):1661–1669PubMed

10.

Ferriero DM (2004) Neonatal brain injury. N Engl J Med 351:1985–1995PubMedCrossRef

11.

Simbrunner J, Riccabona M (2006) Imaging of the neonatal CNS. Eur J Radiol 60(2):133–151PubMedCrossRef

12.

Barkovich AJ, Miller SP, Bartha A et al (2006) MR Imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathy. AJNR Am J Neuroradiol 27(3):533–547PubMed

13.

Boichot C, Walker PM, Durand C et al (2006) Term neonate prognoses after perinatal asphyxia: contributions of MR imaging, MR spectroscopy, relaxation times, and apparent diffusion coefficients. Radiology 239(3):839–848PubMedCrossRef

14.

Blaser S, Feigenbaum A (2004) A neuroimaging approach to inborn errors of metabolism. Neuroimaging Clin N Am 14(2):307–329PubMedCrossRef

15.

Barkovich AJ (2005) Congenital malformations of the brain and skull. In: Pediatric neuroimaging, 4th ed. Lippincott Williams & Wilkins, Philadelphia. pp. 291–439

16.

Vossough A, Zimmerman RA, Bilaniuk LT et al (2008) Imaging findings of neonatal herpes simplex virus type 2 encephalitis. Neuroradiology 50(4):355–366PubMedCrossRef

Title: Imaging of neonatal brain emergencies: multisequence MRI analysis of pathologic spectrum including diffusion and MR spectroscopy
Authors: Asha Ittoop
T. Thomas Zacharia
Publication date: 01-04-2012
Publisher: Springer-Verlag
Published in: Emergency Radiology / Issue 2/2012
Print ISSN: 1070-3004
Electronic ISSN: 1438-1435
DOI: https://doi.org/10.1007/s10140-011-0995-y

At a glance: The STEP trials

Springer Medicine

Imaging of neonatal brain emergencies: multisequence MRI analysis of pathologic spectrum including diffusion and MR spectroscopy

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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