Top

Published in:

01-02-2009 | Review Article

Imaging diabetes mellitus with coronary computed tomography angiography, cardiovascular magnetic resonance, and positron emission tomography

Author: Maleah Grover-McKay, MD

Published in: Journal of Nuclear Cardiology | Issue 1/2009

Abstract

The prevalence and medical expense associated with diabetes mellitus continue to increase. Using the diagnostic imaging techniques of coronary computed tomography angiography, cardiovascular magnetic resonance, and positron emission tomography, it may be possible to make earlier, non-invasive diagnoses of the type and extent of disease, thereby preventing or delaying some morbidity and mortality.

Cardiovascular disease statistics. http://www.americanheart.org/presenter.jhtml?identified=4478. Accessed 1 Nov 2008.

Diabetes incidence and prevalence. http://professional.diabetes.org/Disease_Backgrounder.aspx?TYP=6&MID=236. Accessed 1 Nov 2008.

Direct and indirect costs of diabetes in the United States. http://www.diabetes.org/diabetes-statistics/cost-of-diabetes-in-us.jsp. Accessed 1 Nov 2008.

Eurich D, et al. The darkening cloud of diabetes: Do trends in cardiovascular risk management provide a silver lining? Diabetes Care 2008;31:2136-48.PubMedCrossRef

Raggi P, Bellasi A, Ratti C. Ischemia imaging and plaque imaging in diabetes. Diabetes Care 2005;28:2787-94.PubMedCrossRef

Iwasaki K, et al. Prevalence of subclinical atherosclerosis in asymptomatic diabetic patients by 64-slice computed tomography. Coron Artery Dis 2008;19:195-201.PubMedCrossRef

Zeina AR, et al. Coronary artery disease among asymptomatic diabetic and nondiabetic patients undergoing coronary computed tomography angiography. Coron Artery Dis 2008;19:37-41.PubMedCrossRef

Scholte AJHA, et al. Prevalence of coronary artery disease and plaque morphology assessed by multi-slice computed tomography coronary angiography and calcium scoring in asymptomatic patients with type 2 diabetes. Heart 2008;94:290-5.PubMedCrossRef

Hausleiter J, et al. Prevalence of noncalcified coronary plaques by 64-slice computed tomography in patients with an intermediate risk for significant coronary artery disease. J Am Coll Cardiol 2006;48:312-8.PubMedCrossRef

10.

Morricone L, et al. Relationship of visceral fat distribution to angiographically assessed coronary artery disease: Results in subjects with or without diabetes or impaired glucose tolerance. Nutr Metab Cardiovasc Dis 2002;12:275-83.PubMed

11.

Kim RJ, et al. Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation 1999;100:1992-2002.PubMed

12.

Kwong RY, et al. Incidence and prognostic implication of unrecognized myocardial scar characterized by cardiac magnetic resonance in diabetic patients without clinical evidence of myocardial infarction. Circulation 2008;107:1011-20.CrossRef

13.

Kim WY, et al. Subclinical coronary and aortic atherosclerosis detected by magnetic resonance imaging in type 1 diabetes with and without diabetic nephropathy. Circulation 2007;115:228-35.PubMedCrossRef

14.

Diamant M, et al. Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus. J Am Coll Cardiol 2003;42:328-35.PubMedCrossRef

15.

Scheuermann-Freestone M, et al. Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes. Circulation 2003;107:3040-6.PubMedCrossRef

16.

Perseghin G, et al. Abnormal left ventricular energy metabolism in obese men with preserved systolic and diastolic functions is associated with insulin resistance. Diabetes Care 2007;30:1520-6.PubMedCrossRef

17.

McGavock JM, et al. Cardiac steatosis in diabetes mellitus: A ¹H-magnetic resonance spectroscopy study. Circulation 2007;116:1170-5.PubMedCrossRef

18.

Dong SJ, et al. MRI assessment of LV relaxation by untwisting rate: A new isovolumic phase measure of tau. Am J Physiol Heart Circ Physiol 2001;281:H2002-9.PubMed

19.

Chung J, et al. Paradoxical increase in ventricular torsion and systolic torsion rate in type I diabetic patients under tight glycemic control. J Am Coll Cardiol 2006;47:384-90.PubMedCrossRef

20.

Fonseca CG, et al. Three-dimensional assessment of left ventricular systolic strain in patients with type 2 diabetes mellitus, diastolic dysfunction, and normal ejection fraction. Am J Cardiol 2004;94:1391-5.PubMedCrossRef

21.

Finck BN. Effects of PPARα on cardiac glucose metabolism: A transcriptional equivalent of the glucose-fatty acid cycle? Expert Rev Cardiovasc Ther 2006;4:161-71.PubMedCrossRef

22.

Phillips MS, et al. Leptin receptor missense mutation in the fatty Zucker rat. Nat Genet 1996;13:18-9.PubMedCrossRef

23.

Shoghi K, et al. Time course of alterations in myocardial glucose utilization in the Zucker diabetic fatty rat with correlation to gene expression of glucose transporters: A small-animal PET investigation. J Nucl Med 2008;49:1320-7.PubMedCrossRef

24.

Simoes MV, et al. Delayed response of insulin-stimulated fluorine-18 deoxyglucose uptake in glucose transporter-4-null mice hearts. J Am Coll Cardiol 2004;43:1690-7.PubMedCrossRef

25.

Herrero P, et al. Increased myocardial fatty acid metabolism in patients with type 1 diabetes mellitus. J Am Coll Cardiol 2006;47:598-604.PubMedCrossRef

26.

Peterson LR, et al. Fatty acids and insulin modulate myocardial substrate metabolism in humans with type 1 diabetes. Diabetes 2008;57:32-40.PubMedCrossRef

27.

Herrero P, et al. PET detection of the impact of dobutamine on myocardial glucose metabolism in women with type 1 diabetes mellitus. J Nucl Cardiol 2008;15:791-9.PubMed

28.

Srinivasan M, et al. The effects of plasma insulin and glucose on myocardial blood flow in patients with type 1 diabetes mellitus. J Am Coll Cardiol 2005;46:42-8.PubMedCrossRef

29.

Lautamaki R, et al. Rosiglitazone improves myocardial glucose uptake in patients with type 2 diabetes and coronary artery disease: A 16-week randomized, double-blind, placebo-controlled study. Diabetes 2005;54:2787-94.PubMedCrossRef

Title: Imaging diabetes mellitus with coronary computed tomography angiography, cardiovascular magnetic resonance, and positron emission tomography
Author: Maleah Grover-McKay, MD
Publication date: 01-02-2009
Publisher: Springer-Verlag
Published in: Journal of Nuclear Cardiology / Issue 1/2009
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-008-9038-9

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Imaging diabetes mellitus with coronary computed tomography angiography, cardiovascular magnetic resonance, and positron emission tomography

Abstract

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 1/2009

123I-mIBG Scintigraphy to predict risk for adverse cardiac outcomes in heart failure patients: Design of two prospective multicenter international trials

Impaired myocardial oxidative metabolism in the remote normal region in patients in the chronic phase of myocardial infarction and left ventricular remodeling

ASNC Announcement

The RegEx trial: a randomized, double-blind, placebo- and active-controlled pilot study combining regadenoson, a selective A2A adenosine agonist, with low-level exercise, in patients undergoing myocardial perfusion imaging

ASNC Announcement

Incremental prognostic value of cardiac single-photon emission computed tomography after nitrate administration in patients with ischemic left ventricular dysfunction

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page