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13-06-2022 | IgA Vasculitis | Case Based Review

Vasculitis flare after COVID-19: report of two cases in patients with preexistent controlled IgA vasculitis and review of the literature

Authors: Cristina Valero, Juan Pablo Baldivieso-Achá, Miren Uriarte, Esther F. Vicente-Rabaneda, Santos Castañeda, Rosario García-Vicuña

Published in: Rheumatology International | Issue 9/2022

Abstract

COVID-19 has been related to several autoimmune diseases, triggering the appearance of autoantibodies and endothelial dysfunction. Current evidence has drawn attention to vasculitis-like phenomena and leukocytoclastic vasculitis in some COVID-19 patients. Moreover, it has been hypothesized that COVID-19 could induce flares of preexisting autoimmune disorders. Here, we present two patients with previously controlled IgA vasculitis who developed a renal and cutaneous flare of vasculitis after mild COVID-19, one of them with new-onset ANCA vasculitis. These patients were treated with glucocorticoids and immunosuppressants achieving successful response. We also provide a focused literature review and conclude that COVID-19 may be associated with triggering of vasculitis and could induce flares of previous autoimmune diseases.

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Title: Vasculitis flare after COVID-19: report of two cases in patients with preexistent controlled IgA vasculitis and review of the literature
Authors: Cristina Valero
Juan Pablo Baldivieso-Achá
Miren Uriarte
Esther F. Vicente-Rabaneda
Santos Castañeda
Rosario García-Vicuña
Publication date: 13-06-2022
Publisher: Springer Berlin Heidelberg
Keywords: IgA Vasculitis
ANCA-Associated Vasculitis
Vasculitis
IgA Vasculitis
ANCA-Associated Vasculitis
Vasculitis
Leukocytoclastic Vasculitis
Leukocytoclastic Vasculitis
Glucocorticoid
Rituximab
SARS-CoV-2
Pneumonia
COVID-19
Glomerulonephritis
Rituximab
Published in: Rheumatology International / Issue 9/2022
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-022-05153-w

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