Skip to main content
Top
Published in: Osteoporosis International 5/2018

01-05-2018 | Review

Identifying characteristics of an effective fracture liaison service: systematic literature review

Authors: C.-H. Wu, C.-H. Chen, P.-H. Chen, J.-J. Yang, P.-C. Chang, T.-C. Huang, S. Bagga, Y. Sharma, R.-M. Lin, D.-C. Chan

Published in: Osteoporosis International | Issue 5/2018

Login to get access

Abstract

Fracture liaison services (FLS) have been demonstrated to improve outcomes following osteoporotic fracture. The aim of this systematic literature review (SLR) was to determine the characteristics of an FLS that lead to improved patient outcomes. We conducted a SLR, including articles published between 2000 and February 2017, using global (Medline, EMBASE, PubMed and Cochrane Library) and local databases. Studies including patients aged ≥ 50 years with osteoporotic fractures enrolled in an FLS were assessed. Information extracted from each article included key person coordinating the FLS (physician, nurse or other healthcare professional), setting (hospital vs community), intensity (single vs multiple), duration (long vs short term), fracture type and gender. A meta-analysis of randomised controlled trials was conducted based on the key person coordinating the FLS. Out of 7236 articles, 57 were considered to be high quality and identified for further analysis. The SLR identified several components which contributed to FLS success, including multidisciplinary involvement, driven by a dedicated case manager, regular assessment and follow-up, multifaceted interventions and patient education. Meta-analytic data confirm the effectiveness of an FLS following an osteoporotic fracture: approximate 27% increase in the likelihood of BMD testing and up to 21% increase in the likelihood of treatment initiation compared with usual care. The balance of evidence indicates that the multifaceted FLS and dedicated coordination are important success factors that contribute to effective FLS interventions which reduce fracture-related morbidity and mortality.
Appendix
Available only for authorised users
Literature
3.
go back to reference Ensrud K (2013) Epidemiology of fracture risk with advancing age. J Gerontol 68(10):1236–1242CrossRef Ensrud K (2013) Epidemiology of fracture risk with advancing age. J Gerontol 68(10):1236–1242CrossRef
5.
go back to reference Strom O, Borgström F, Kanis JA, Compstom J, Cooper C, McCloskey EV, Jonsson B (2011) Osteoporosis: burden, health care provision and opportunities in the EU: a report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos 1–98 Strom O, Borgström F, Kanis JA, Compstom J, Cooper C, McCloskey EV, Jonsson B (2011) Osteoporosis: burden, health care provision and opportunities in the EU: a report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Arch Osteoporos 1–98
10.
go back to reference Kung AWFT, Xu L, Xia WB, Park IH, Sun K, Chan SW, Lee JK, Koh L, Soog YK, Soontrapa S, Songpatanaslip T, Turajane T, Yates M, Sen S (2013) Factors influencing diagnosis and treatment of osteoporosis after a fragility fracture among postmenopausal women in Asian countries: a retrospective study. BMC Women’s Health 13(7):1–7 Kung AWFT, Xu L, Xia WB, Park IH, Sun K, Chan SW, Lee JK, Koh L, Soog YK, Soontrapa S, Songpatanaslip T, Turajane T, Yates M, Sen S (2013) Factors influencing diagnosis and treatment of osteoporosis after a fragility fracture among postmenopausal women in Asian countries: a retrospective study. BMC Women’s Health 13(7):1–7
18.
go back to reference Abou-Raya SA-RA, Khadrawi T (2013) AB0627 a randomized controlled trial of early initiation of osteoporosis assessment and management in the acute setting of the fracture clinic. Ann Rheum Dis 72:A981CrossRef Abou-Raya SA-RA, Khadrawi T (2013) AB0627 a randomized controlled trial of early initiation of osteoporosis assessment and management in the acute setting of the fracture clinic. Ann Rheum Dis 72:A981CrossRef
21.
go back to reference Cranney A, Lam M, Ruhland L, Brison R, Godwin M, Harrison MM, Harrison MB, Anastassiades T, Grimshaw JM, Graham ID (2008) A multifaceted intervention to improve treatment of osteoporosis in postmenopausal women with wrist fractures: a cluster randomized trial. Osteoporos Int 19(12):1733–1740. https://doi.org/10.1007/s00198-008-0669-0 CrossRefPubMed Cranney A, Lam M, Ruhland L, Brison R, Godwin M, Harrison MM, Harrison MB, Anastassiades T, Grimshaw JM, Graham ID (2008) A multifaceted intervention to improve treatment of osteoporosis in postmenopausal women with wrist fractures: a cluster randomized trial. Osteoporos Int 19(12):1733–1740. https://​doi.​org/​10.​1007/​s00198-008-0669-0 CrossRefPubMed
22.
go back to reference Davis J, Guy P, Ashe M, Liu-Ambrose T, Khan K (2007) HipWatch: osteoporosis investigation and treatment after a hip fracture: a 6-month randomized controlled trial. J Gerontol Med Sci 62a(8):888–891CrossRef Davis J, Guy P, Ashe M, Liu-Ambrose T, Khan K (2007) HipWatch: osteoporosis investigation and treatment after a hip fracture: a 6-month randomized controlled trial. J Gerontol Med Sci 62a(8):888–891CrossRef
24.
25.
go back to reference Gardner MJ, Brophy R, Demetrakopoulos D, Koob J, Hong R, Rana A et al (2005) Interventions to improve osteoporosis treatment following hip fracture: a prospective, randomized trial. J Bone Joint Surg 87a(1):3–7CrossRef Gardner MJ, Brophy R, Demetrakopoulos D, Koob J, Hong R, Rana A et al (2005) Interventions to improve osteoporosis treatment following hip fracture: a prospective, randomized trial. J Bone Joint Surg 87a(1):3–7CrossRef
26.
go back to reference Jaglal SB, Donescu OS, Bansod V, Laprade J, Thorpe K, Hawker G, Majumdar SR, Meadows L, Cadarette SM, Papaioannou A, Kloseck M, Beaton D, Bogoch E, Zwarenstein M (2012) Impact of a centralized osteoporosis coordinator on post-fracture osteoporosis management: a cluster randomized trial. Osteoporos Int 23(1):87–95. https://doi.org/10.1007/s00198-011-1726-7 CrossRefPubMed Jaglal SB, Donescu OS, Bansod V, Laprade J, Thorpe K, Hawker G, Majumdar SR, Meadows L, Cadarette SM, Papaioannou A, Kloseck M, Beaton D, Bogoch E, Zwarenstein M (2012) Impact of a centralized osteoporosis coordinator on post-fracture osteoporosis management: a cluster randomized trial. Osteoporos Int 23(1):87–95. https://​doi.​org/​10.​1007/​s00198-011-1726-7 CrossRefPubMed
28.
go back to reference Majumdar SR, Johnson JA, Lier DA, Russell AS, Hanley DA, Blitz S, Steiner IP, Maksymowych WP, Morrish DW, Holroyd BR, Rowe BH (2007) Persistence, reproducibility, and cost-effectiveness of an intervention to improve the quality of osteoporosis care after a fracture of the wrist: results of a controlled trial. Osteoporos Int 18(3):261–270. https://doi.org/10.1007/s00198-006-0248-1 CrossRefPubMed Majumdar SR, Johnson JA, Lier DA, Russell AS, Hanley DA, Blitz S, Steiner IP, Maksymowych WP, Morrish DW, Holroyd BR, Rowe BH (2007) Persistence, reproducibility, and cost-effectiveness of an intervention to improve the quality of osteoporosis care after a fracture of the wrist: results of a controlled trial. Osteoporos Int 18(3):261–270. https://​doi.​org/​10.​1007/​s00198-006-0248-1 CrossRefPubMed
33.
go back to reference Morrish DW, Beaupre LA, Bell NR, Cinats JG, Hanley DA, Harley CH, Juby AG, Lier DA, Maksymowych WP, Majumdar SR (2009) Facilitated bone mineral density testing versus hospital-based case management to improve osteoporosis treatment for hip fracture patients: additional results from a randomized trial. Arthritis Rheum 61(2):209–215. https://doi.org/10.1002/art.24097 CrossRefPubMed Morrish DW, Beaupre LA, Bell NR, Cinats JG, Hanley DA, Harley CH, Juby AG, Lier DA, Maksymowych WP, Majumdar SR (2009) Facilitated bone mineral density testing versus hospital-based case management to improve osteoporosis treatment for hip fracture patients: additional results from a randomized trial. Arthritis Rheum 61(2):209–215. https://​doi.​org/​10.​1002/​art.​24097 CrossRefPubMed
39.
go back to reference Majumdar SR, Johnson JA, Bellerose D, McAlister FA, Russell AS, Hanley DA, Garg S, Lier DA, Maksymowych WP, Morrish DW, Rowe BH (2011) Nurse case-manager vs multifaceted intervention to improve quality of osteoporosis care after wrist fracture: randomized controlled pilot study. Osteoporos Int 22(1):223–230. https://doi.org/10.1007/s00198-010-1212-7 CrossRefPubMed Majumdar SR, Johnson JA, Bellerose D, McAlister FA, Russell AS, Hanley DA, Garg S, Lier DA, Maksymowych WP, Morrish DW, Rowe BH (2011) Nurse case-manager vs multifaceted intervention to improve quality of osteoporosis care after wrist fracture: randomized controlled pilot study. Osteoporos Int 22(1):223–230. https://​doi.​org/​10.​1007/​s00198-010-1212-7 CrossRefPubMed
47.
go back to reference Hawker G, Ridout R, Ricupero M, Jaglal S, Bogoch E (2003) The impact of a simple fracture clinic intervention in improving the diagnosis and treatment of osteoporosis in fragility fracture patients. Osteoporos Int 14(2):171–178CrossRefPubMed Hawker G, Ridout R, Ricupero M, Jaglal S, Bogoch E (2003) The impact of a simple fracture clinic intervention in improving the diagnosis and treatment of osteoporosis in fragility fracture patients. Osteoporos Int 14(2):171–178CrossRefPubMed
49.
go back to reference Jaglal SB, Hawker G, Bansod V, Salbach NM, Zwarenstein M, Carroll J, Brooks D, Cameron C, Bogoch E, Jaakkimainen L, Kreder H (2009) A demonstration project of a multi-component educational intervention to improve integrated post-fracture osteoporosis care in five rural communities in Ontario, Canada. Osteoporos Int 20(2):265–274. https://doi.org/10.1007/s00198-008-0654-7 CrossRefPubMed Jaglal SB, Hawker G, Bansod V, Salbach NM, Zwarenstein M, Carroll J, Brooks D, Cameron C, Bogoch E, Jaakkimainen L, Kreder H (2009) A demonstration project of a multi-component educational intervention to improve integrated post-fracture osteoporosis care in five rural communities in Ontario, Canada. Osteoporos Int 20(2):265–274. https://​doi.​org/​10.​1007/​s00198-008-0654-7 CrossRefPubMed
54.
go back to reference van Geel TA, Bliuc D, Geusens P, Center J, Dinant GJ, Eisman J, Van den Bergh J, McLellan A (2013) Subsequent fracture risk and mortality in the Glasgow fracture liaison service: an 8-year follow-up study. J Bone Min Res 28 van Geel TA, Bliuc D, Geusens P, Center J, Dinant GJ, Eisman J, Van den Bergh J, McLellan A (2013) Subsequent fracture risk and mortality in the Glasgow fracture liaison service: an 8-year follow-up study. J Bone Min Res 28
56.
go back to reference Hofflich HL, Oh DK, Choe CH, Clay B, Tibble C, Kulasa KM, Shah PK, Fink E, Girard PJ, Schwartz AK, Maynard GA (2014) Using a triggered endocrinology service consultation to improve the evaluation, management, and follow-up of osteoporosis in hip-fracture patients. Jt Comm J Qual Patient Saf 40(5):228–AP1. https://doi.org/10.1016/S1553-7250(14)40030-8 CrossRefPubMed Hofflich HL, Oh DK, Choe CH, Clay B, Tibble C, Kulasa KM, Shah PK, Fink E, Girard PJ, Schwartz AK, Maynard GA (2014) Using a triggered endocrinology service consultation to improve the evaluation, management, and follow-up of osteoporosis in hip-fracture patients. Jt Comm J Qual Patient Saf 40(5):228–AP1. https://​doi.​org/​10.​1016/​S1553-7250(14)40030-8 CrossRefPubMed
58.
go back to reference van Helden S (2008) Looking beyond the fracture: prevention in fracture care: Doctoral Thesis—Maastricht: Maastricht University van Helden S (2008) Looking beyond the fracture: prevention in fracture care: Doctoral Thesis—Maastricht: Maastricht University
60.
go back to reference Wallace I, Callachand F, Elliott J, Gardiner P (2011) An evaluation of an enhanced fracture liaison service as the optimal model for secondary prevention of osteoporosis. JRSM Short Rep 2(2):8CrossRefPubMedPubMedCentral Wallace I, Callachand F, Elliott J, Gardiner P (2011) An evaluation of an enhanced fracture liaison service as the optimal model for secondary prevention of osteoporosis. JRSM Short Rep 2(2):8CrossRefPubMedPubMedCentral
62.
go back to reference Beaton DE, Vidmar M, Pitzul KB, Sujic R, Rotondi NK, Bogoch ER, Sale JEM, Jain R, Weldon J (2017) Addition of a fracture risk assessment to a coordinator’s role improved treatment rates within 6 months of screening in a fragility fracture screening program. Osteoporos Int 28(3):863–869. https://doi.org/10.1007/s00198-016-3794-1 CrossRefPubMed Beaton DE, Vidmar M, Pitzul KB, Sujic R, Rotondi NK, Bogoch ER, Sale JEM, Jain R, Weldon J (2017) Addition of a fracture risk assessment to a coordinator’s role improved treatment rates within 6 months of screening in a fragility fracture screening program. Osteoporos Int 28(3):863–869. https://​doi.​org/​10.​1007/​s00198-016-3794-1 CrossRefPubMed
68.
go back to reference Streetan E, Mohamed A, Gandhi A, Orwig D, Sack P, Sterling R et al (2006) The inpatient consultation approach to osteoporosis treatment in patients with a fracture. J Bone Joint Surg 88a(9):1968–1974 Streetan E, Mohamed A, Gandhi A, Orwig D, Sack P, Sterling R et al (2006) The inpatient consultation approach to osteoporosis treatment in patients with a fracture. J Bone Joint Surg 88a(9):1968–1974
74.
go back to reference Compston J, Cooper A, Cooper C, Gittoes N, Gregson C, Harvey N, Hope S, Kanis JA, McCloskey EV, Poole KES, Reid DM, Selby P, Thompson F, Thurston A, Vine N, Osteoporosis Guideline Group (NOGG) (2017) UK clinical guideline for the prevention and treatment of osteoporosis. Arch Osteoporos 12:43. https://doi.org/10.1007/s11657-017-0324-5 Compston J, Cooper A, Cooper C, Gittoes N, Gregson C, Harvey N, Hope S, Kanis JA, McCloskey EV, Poole KES, Reid DM, Selby P, Thompson F, Thurston A, Vine N, Osteoporosis Guideline Group (NOGG) (2017) UK clinical guideline for the prevention and treatment of osteoporosis. Arch Osteoporos 12:43. https://​doi.​org/​10.​1007/​s11657-017-0324-5
80.
go back to reference Papaioannou A, Morin S, Cheung AM, Atkinson S, Brown JP, Feldman S, Hanley DA, Hodsman A, Jamal SA, Kaiser SM, Kvern B, Siminoski K, Leslie WD, for the Scientific Advisory Council of Osteoporosis Canada (2010) 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. Can Med Assoc J 182(7):1864–1873. https://doi.org/10.1503/cmaj.100771 CrossRef Papaioannou A, Morin S, Cheung AM, Atkinson S, Brown JP, Feldman S, Hanley DA, Hodsman A, Jamal SA, Kaiser SM, Kvern B, Siminoski K, Leslie WD, for the Scientific Advisory Council of Osteoporosis Canada (2010) 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. Can Med Assoc J 182(7):1864–1873. https://​doi.​org/​10.​1503/​cmaj.​100771 CrossRef
Metadata
Title
Identifying characteristics of an effective fracture liaison service: systematic literature review
Authors
C.-H. Wu
C.-H. Chen
P.-H. Chen
J.-J. Yang
P.-C. Chang
T.-C. Huang
S. Bagga
Y. Sharma
R.-M. Lin
D.-C. Chan
Publication date
01-05-2018
Publisher
Springer London
Published in
Osteoporosis International / Issue 5/2018
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-017-4370-z

Other articles of this Issue 5/2018

Osteoporosis International 5/2018 Go to the issue