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01-08-2015 | “How To” Article

I-123 MIBG Cardiac Imaging

Authors: Prem Soman, MD, PhD, FASNC, Mark I. Travin, MD, FASNC, Myron Gerson, MD, FASNC, S. James Cullom, PhD, DABR, Randall Thompson, MD, FASNC

Published in: Journal of Nuclear Cardiology | Issue 4/2015

Excerpt

I-123 metaiodobenzylguanidine (MIBG) is a radionuclide tracer that can be used to image the function of myocardial sympathetic nerve terminals. It is an analog of guanethidine, a false neurotransmitter that is structurally similar to the sympathetic neurotransmitter norepinephrine. The kinetics of I-123 MIBG at the sympathetic nerve terminal reflects adrenergic activity and thus, it can be used to image sympathetic nerve terminal function. 1-123 MIBG for cardiac imaging is marketed as Adreview^TM (GE Healthcare).1 …

Healthcare G. Adrview^TM Iobenguane I-123 Injection Prescribing Infomation. 2013.

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Title: I-123 MIBG Cardiac Imaging
Authors: Prem Soman, MD, PhD, FASNC
Mark I. Travin, MD, FASNC
Myron Gerson, MD, FASNC
S. James Cullom, PhD, DABR
Randall Thompson, MD, FASNC
Publication date: 01-08-2015
Publisher: Springer US
Published in: Journal of Nuclear Cardiology / Issue 4/2015
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-015-0108-5

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