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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 1/2022

01-01-2022 | Hypertensive Emergency | Editorial Commentary

Acute Severe Hypertension in Children: An Ongoing Search for Therapeutic Agent of Choice

Authors: Nitin Dhochak, Rakesh Lodha

Published in: Indian Journal of Pediatrics | Issue 1/2022

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Excerpt

Children with acute severe hypertension present to pediatric emergency with end-organ dysfunction (hypertensive emergency); this demands prompt therapy. The blood pressure cutoffs for acute severe hypertension are not very clear and vary among guidelines: (a) 30 mm Hg or more above the 95th centile (2017 American Academy of Pediatrics guidelines); (b) 20% above the stage 2 hypertension limit (2016 European Society of Hypertension guidelines) [1, 2]. Both guidelines also mention that these are commonly used cutoffs but children may have features of end-organ dysfunction even at lower blood pressures, if the blood pressure rise is abrupt. …
Literature
1.
Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, et al. Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics. 2017;140:e20171904.
2.
Lurbe E, Agabiti-Rosei E, Cruickshank JK, et al. European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents. J Hypertens. 2016;34:1887–920.CrossRef
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4.
Tabbutt S, Nicolson SC, Adamson PC, et al. The safety, efficacy, and pharmacokinetics of esmolol for blood pressure control immediately after repair of coarctation of the aorta in infants and children: a multicenter, double-blind, randomized trial. J Thorac Cardiovasc Surg. 2008;136:321–8.CrossRef
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Hari P, Sinha A. Hypertensive emergencies in children. Indian J Pediatr. 2011;78:569–75.CrossRef
Metadata
Title
Acute Severe Hypertension in Children: An Ongoing Search for Therapeutic Agent of Choice
Authors
Nitin Dhochak
Rakesh Lodha
Publication date
01-01-2022
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 1/2022
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-021-04036-5

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