ASO Author Reflections: Utility of New ^99mTc-MIBI Scintigraphy Before Reoperating Patients with Persistent Sporadic Primary Hyperparathyroidism: Results of a Retrospective Multicenter Study

Excerpt

As parathyroidectomy is the only curative treatment for primary hyperparathyroidism (PHPT), focused surgical approaches are preferred, making preoperative localization imaging mandatory. The combined use of ultrasound scanning (US) and ^99mTc methoxyisobutylisonitrile (MIBI) scintigraphy is the most frequently used strategy.1 Despite a high cure rate, PHPT persists in 2.5–15% of patients.2 Persistent PHPT is defined as failure of cure within 6 months after surgery. In case of persistent PHPT, redo surgery exposes patients to higher morbidity and failure rate, and preoperative imaging studies are strongly needed.3 Studying a cohort of 50 patients who we failed to cure with first surgery preceded by MIBI scintigraphy in three tertiary referral centers, we aimed to study the interest in repeating this exam before redo surgery in persistent sporadic PHPT. …