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Published in: BMC Endocrine Disorders 1/2023

Open Access 06-07-2023 | Hyperparathyroidism | Case report

Selective venous sampling in primary hyperparathyroidism caused by ectopic parathyroid gland: a case report and literature review

Authors: Xubin Yang, Xueyan Chen, Huan Xu, Junwei Chen, Bin Yao, Qiongyan Lin, Hongrong Deng, Wen Xu

Published in: BMC Endocrine Disorders | Issue 1/2023

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Abstract

Background

As an invasive technique, selective venous sampling (SVS) is considered a useful method to identify a lesion’s location to increase the success rate of secondary surgery in patients with primary hyperparathyroidism (pHPT) caused by ectopic parathyroid adenomas.

Case presentation

We present a case of post-surgical persistent hypercalcemia and elevated parathyroid hormone (PTH) levels in a 44-year-old woman with previously undetected parathyroid adenoma. An SVS was then performed for further localization of the adenoma, as other non-invasive methods showed negative results. After SVS, an ectopic adenoma was suspected in the sheath of the left carotid artery, previously considered as a schwannoma, and was pathologically confirmed after the second operation. Postoperatively, the patient’s symptoms disappeared and serum levels of PTH and calcium normalized.

Conclusions

SVS can provide precise diagnosis and accurate positioning before re-operation in patients with pHPT.
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Metadata
Title
Selective venous sampling in primary hyperparathyroidism caused by ectopic parathyroid gland: a case report and literature review
Authors
Xubin Yang
Xueyan Chen
Huan Xu
Junwei Chen
Bin Yao
Qiongyan Lin
Hongrong Deng
Wen Xu
Publication date
06-07-2023
Publisher
BioMed Central
Published in
BMC Endocrine Disorders / Issue 1/2023
Electronic ISSN: 1472-6823
DOI
https://doi.org/10.1186/s12902-023-01376-5

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