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Published in: CEN Case Reports 4/2023

12-03-2023 | Hyperkalemia | Case Report

Marked hyperkalemia due to inappropriate blood sample storage in two suspected cases of familial pseudohyperkalemia

Authors: Katsuhisa Kuwano, Sayaka Shimizu, Yoko Fujita, Satoshi Akatsu, Yugo Shibagaki, Masahiko Yazawa

Published in: CEN Case Reports | Issue 4/2023

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Abstract

We herein report two suspected cases of pseudohyperkalemia who presented with severe hyperkalemia examined at small primary care clinics; however, re-exams at a tertiary care hospital showed normal potassium levels. We reproduced the laboratory examination conditions of the clinics and found that hyperkalemia was due to sampling/storage condition of serum, which is strongly suggestive of familial pseudohyperkalemia (FP). FP is a possible but under-appreciated cause of hyperkalemia, which does not require treatment, so it is important to include FP in the differential diagnosis of hyperkalemia especially in cases with discrepant of serum potassium levels at different settings.
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Metadata
Title
Marked hyperkalemia due to inappropriate blood sample storage in two suspected cases of familial pseudohyperkalemia
Authors
Katsuhisa Kuwano
Sayaka Shimizu
Yoko Fujita
Satoshi Akatsu
Yugo Shibagaki
Masahiko Yazawa
Publication date
12-03-2023
Publisher
Springer Nature Singapore
Keyword
Hyperkalemia
Published in
CEN Case Reports / Issue 4/2023
Electronic ISSN: 2192-4449
DOI
https://doi.org/10.1007/s13730-023-00781-y

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