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Published in: Medical Gas Research 1/2011

Open Access 01-12-2011 | Case report

Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports

Author: Kenneth P Stoller

Published in: Medical Gas Research | Issue 1/2011

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Abstract

Despite adequate evidence, including randomized controlled trials; hyperbaric oxygen is not yet recognized as efficacious for treating various forms of brain injury, specifically traumatic brain injury. Political-economic issues have kept this benign therapy from being widely adopted despite the lack of viable alternatives. Two football players with TBI/CTE are herewith shown to benefit from being treated with hyperbaric oxygen as documented by neurocognitive examinations and functional brain imaging, in one case treatment commenced decades after the brain injury. Perhaps the interest in HBOT by those participating in high-risk sports will help expand this orphan therapy into mainstream medicine.
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Literature
1.
go back to reference Sluiter ME: The treatment of carbon monoxide poisoning by the administration of oxygen at high atmospheric pressure. Proc R Soc Med. 1963, 1002-8. 56 Sluiter ME: The treatment of carbon monoxide poisoning by the administration of oxygen at high atmospheric pressure. Proc R Soc Med. 1963, 1002-8. 56
3.
go back to reference Stoller KP: Hyperbaric oxygen and carbon monoxide poisoning: a critical review. Neurological Research. 2007, 29: 146-155. 10.1179/016164107X181770.CrossRefPubMed Stoller KP: Hyperbaric oxygen and carbon monoxide poisoning: a critical review. Neurological Research. 2007, 29: 146-155. 10.1179/016164107X181770.CrossRefPubMed
4.
go back to reference Duff JH, Shibata HR, Vanschaik L, Usher R, Wigmore RA, MacLean LD: Hyperbaric oxygen: a review of treatment in eighty-three patients. Can Med Assoc J. 1967, 97 (10): 510-5.PubMedCentralPubMed Duff JH, Shibata HR, Vanschaik L, Usher R, Wigmore RA, MacLean LD: Hyperbaric oxygen: a review of treatment in eighty-three patients. Can Med Assoc J. 1967, 97 (10): 510-5.PubMedCentralPubMed
5.
go back to reference Workman RD: Oxygen decompression following air dives for use in hyperbaric oxygen therapy. Res Rep 2-64. Rep US Navy Exp Diving Unit. 1964 Dec 15:1-10 Workman RD: Oxygen decompression following air dives for use in hyperbaric oxygen therapy. Res Rep 2-64. Rep US Navy Exp Diving Unit. 1964 Dec 15:1-10
6.
go back to reference Hart GB, Thompson RE: The treatment of cerebral ischemia with hyperbaric oxygen (OHP). Stroke. 1971, 2 (3): 247-50. 10.1161/01.STR.2.3.247.CrossRefPubMed Hart GB, Thompson RE: The treatment of cerebral ischemia with hyperbaric oxygen (OHP). Stroke. 1971, 2 (3): 247-50. 10.1161/01.STR.2.3.247.CrossRefPubMed
7.
go back to reference Neubauer RA, James P: Cerebral oxygenation and the recoverable brain. Neurol Res. 1998, 20 (Suppl 1): S33-6.PubMed Neubauer RA, James P: Cerebral oxygenation and the recoverable brain. Neurol Res. 1998, 20 (Suppl 1): S33-6.PubMed
8.
go back to reference Chang DC, Lee JT, Lo CP, Fan YM, Huang KL, Kang BH, Hsieh HL, Chen SY: Hyperbaric oxygen ameliorates delayed neuropsychiatric syndrome of carbon monoxide poisoning. Undersea Hyperb Med. 2010, 37 (1): 23-33.PubMed Chang DC, Lee JT, Lo CP, Fan YM, Huang KL, Kang BH, Hsieh HL, Chen SY: Hyperbaric oxygen ameliorates delayed neuropsychiatric syndrome of carbon monoxide poisoning. Undersea Hyperb Med. 2010, 37 (1): 23-33.PubMed
9.
go back to reference Senol MG, Yildiz S, Ersanli D, Uzun G, Gumus T, Narin Y, Ozkan S, Ayata A: Carbon monoxide-induced cortical visual loss: treatment with hyperbaric oxygen four years later. Med Princ Pract. 2009, 18 (1): 67-9. 10.1159/000163050.CrossRefPubMed Senol MG, Yildiz S, Ersanli D, Uzun G, Gumus T, Narin Y, Ozkan S, Ayata A: Carbon monoxide-induced cortical visual loss: treatment with hyperbaric oxygen four years later. Med Princ Pract. 2009, 18 (1): 67-9. 10.1159/000163050.CrossRefPubMed
10.
go back to reference Stoller KP: Hyperbaric oxygen and carbon monoxide poisoning: a critical review. Neurological Research. 2007, 29: 146-155. 10.1179/016164107X181770.CrossRefPubMed Stoller KP: Hyperbaric oxygen and carbon monoxide poisoning: a critical review. Neurological Research. 2007, 29: 146-155. 10.1179/016164107X181770.CrossRefPubMed
11.
go back to reference Clifton GL: Hypothermia and hyperbaric oxygen as treatment modalities for severe head injury. New Horiz. 1995, 3 (3): 474-8. ReviewPubMed Clifton GL: Hypothermia and hyperbaric oxygen as treatment modalities for severe head injury. New Horiz. 1995, 3 (3): 474-8. ReviewPubMed
12.
go back to reference Harch PG, Van Meter KW, Gottlieb SF, Staab P: HMPAO SPECT brain imaging and low pressure HBOT in the diagnosis and treatment of chronic traumatic, ischemic, hypoxic and anoxic encephalopathies. Undersea and Hyperbaric Medicine. 1994, 21 (Suppl): 30- Harch PG, Van Meter KW, Gottlieb SF, Staab P: HMPAO SPECT brain imaging and low pressure HBOT in the diagnosis and treatment of chronic traumatic, ischemic, hypoxic and anoxic encephalopathies. Undersea and Hyperbaric Medicine. 1994, 21 (Suppl): 30-
13.
go back to reference Harch PG, Van Meter KW, Neubauer RA, Gottlieb SF: Use of HMPAO SPECT for assessment of response to HBO in ischemic/hypoxic encephalopathies. Textbook of Hyperbaric Medicine, Appendix. Edited by: Jain KK. 1996, Seattle (WA): Hogrefe &Huber Pubs, 480-491. 2 Harch PG, Van Meter KW, Neubauer RA, Gottlieb SF: Use of HMPAO SPECT for assessment of response to HBO in ischemic/hypoxic encephalopathies. Textbook of Hyperbaric Medicine, Appendix. Edited by: Jain KK. 1996, Seattle (WA): Hogrefe &Huber Pubs, 480-491. 2
14.
go back to reference Harch PG, Neubauer RA: Hyperbaric oxygen therapy in global cerebral ischemia/anoxia and coma. Textbook of Hyperbaric Medicine. Edited by: Jain KK. 1999, Hogrefe & Huber Publishers, Seattle WA, Chapter 18: 319-345. 3 Harch PG, Neubauer RA: Hyperbaric oxygen therapy in global cerebral ischemia/anoxia and coma. Textbook of Hyperbaric Medicine. Edited by: Jain KK. 1999, Hogrefe & Huber Publishers, Seattle WA, Chapter 18: 319-345. 3
15.
go back to reference Harch PG, Neubauer RA: Hyperbaric oxygen therapy in global cerebral ischemia/anoxia and coma. Textbook of Hyperbaric Medicine. Edited by: Jain KK. 1999, Hogrefe & Huber Publishers, Seattle WA, Chapter 18: 319-345. 3 Harch PG, Neubauer RA: Hyperbaric oxygen therapy in global cerebral ischemia/anoxia and coma. Textbook of Hyperbaric Medicine. Edited by: Jain KK. 1999, Hogrefe & Huber Publishers, Seattle WA, Chapter 18: 319-345. 3
16.
go back to reference Neubauer RA, Gottlieb SF, Pevsner NH: Hyperbaric Oxygen for Treatment of Closed Head Injury. Southern Medical Journal. 1994, 87 (9): 933-936. 10.1097/00007611-199409000-00015.CrossRefPubMed Neubauer RA, Gottlieb SF, Pevsner NH: Hyperbaric Oxygen for Treatment of Closed Head Injury. Southern Medical Journal. 1994, 87 (9): 933-936. 10.1097/00007611-199409000-00015.CrossRefPubMed
17.
go back to reference Barrett KF, Masel BE, Harch PG, Ingram F, Corson KP, Mader JT: Cerebral blood flow changes and cognitive improvement in chronic stable traumatic brain injuries treated with hyperbaric oxygen therapy. Neurol. 1998, A178-A179. Suppl Barrett KF, Masel BE, Harch PG, Ingram F, Corson KP, Mader JT: Cerebral blood flow changes and cognitive improvement in chronic stable traumatic brain injuries treated with hyperbaric oxygen therapy. Neurol. 1998, A178-A179. Suppl
18.
go back to reference Harch PG, Andrews SR, Fogarty E, Lucarini J, Aubrey C, Staab PK, Van Meter KW: Hyperbaric Oxygen Therapy Treatment of Chronic Mild-Moderate Blast-Induced Traumatic Brain Injury/Post Concussion Syndrome with Post Traumatic Stress Disorder: Pilot Trial. Presented at 8th World Congress on Brain Injury. 2010, Washington DC Harch PG, Andrews SR, Fogarty E, Lucarini J, Aubrey C, Staab PK, Van Meter KW: Hyperbaric Oxygen Therapy Treatment of Chronic Mild-Moderate Blast-Induced Traumatic Brain Injury/Post Concussion Syndrome with Post Traumatic Stress Disorder: Pilot Trial. Presented at 8th World Congress on Brain Injury. 2010, Washington DC
19.
go back to reference Harch PG, Fogarty EF, Staab PK, Van Meter K: Low pressure hyperbaric oxygen therapy and SPECT brain imaging in the treatment of blast-induced chronic traumatic brain injury (post-concussion syndrome) and post traumatic stress disorder: a case report. Cases J. 2009, 2: 6538-10.4076/1757-1626-2-6538.PubMedCentralCrossRefPubMed Harch PG, Fogarty EF, Staab PK, Van Meter K: Low pressure hyperbaric oxygen therapy and SPECT brain imaging in the treatment of blast-induced chronic traumatic brain injury (post-concussion syndrome) and post traumatic stress disorder: a case report. Cases J. 2009, 2: 6538-10.4076/1757-1626-2-6538.PubMedCentralCrossRefPubMed
20.
go back to reference Wright JK, Zant E, Groom K, Schlegel RE, Gilliland K: Case report: Treatment of mild traumatic brain injury with hyperbaric oxygen. Undersea Hyperb Med. 2009, 36 (6): 391-9.PubMed Wright JK, Zant E, Groom K, Schlegel RE, Gilliland K: Case report: Treatment of mild traumatic brain injury with hyperbaric oxygen. Undersea Hyperb Med. 2009, 36 (6): 391-9.PubMed
21.
go back to reference Lin JW, Tsai JT, Lee LM, Lin CM, Hung CC, Hung KS, Chen WY, Wei L, Ko CP, Su YK, Chiu WT: Effect of hyperbaric oxygen on patients with traumatic brain injury. Acta Neurochir Suppl. 2008, 101: 145-9. 10.1007/978-3-211-78205-7_25.CrossRefPubMed Lin JW, Tsai JT, Lee LM, Lin CM, Hung CC, Hung KS, Chen WY, Wei L, Ko CP, Su YK, Chiu WT: Effect of hyperbaric oxygen on patients with traumatic brain injury. Acta Neurochir Suppl. 2008, 101: 145-9. 10.1007/978-3-211-78205-7_25.CrossRefPubMed
22.
go back to reference Rockswold SB, Rockswold GL, Zaun DA, Zhang X, Cerra CE, Bergman TA, Liu J: A prospective, randomized clinical trial to compare the effect of hyperbaric to normobaric hyperoxia on cerebral metabolism, intracranial pressure, and oxygen toxicity in severe traumatic brain injury. J Neurosurg. 2010, 112 (5): 1080-94. 10.3171/2009.7.JNS09363.CrossRefPubMed Rockswold SB, Rockswold GL, Zaun DA, Zhang X, Cerra CE, Bergman TA, Liu J: A prospective, randomized clinical trial to compare the effect of hyperbaric to normobaric hyperoxia on cerebral metabolism, intracranial pressure, and oxygen toxicity in severe traumatic brain injury. J Neurosurg. 2010, 112 (5): 1080-94. 10.3171/2009.7.JNS09363.CrossRefPubMed
23.
go back to reference Rockswold SB, Rockswold GL, Defillo A: Hyperbaric oxygen in traumatic brain injury. Neurol Res. 2007, 29 (2): 162-72. 10.1179/016164107X181798. ReviewCrossRefPubMed Rockswold SB, Rockswold GL, Defillo A: Hyperbaric oxygen in traumatic brain injury. Neurol Res. 2007, 29 (2): 162-72. 10.1179/016164107X181798. ReviewCrossRefPubMed
24.
go back to reference Rockswold SB, Rockswold GL, Defillo A: Hyperbaric oxygen in traumatic brain injury. Neurol Res. 2007, 29 (2): 162-72. 10.1179/016164107X181798. ReviewCrossRefPubMed Rockswold SB, Rockswold GL, Defillo A: Hyperbaric oxygen in traumatic brain injury. Neurol Res. 2007, 29 (2): 162-72. 10.1179/016164107X181798. ReviewCrossRefPubMed
25.
go back to reference Hardy P, Johnston KM, De Beaumont L, Montgomery DL, Lecomte JM, Soucy JP, Bourbonnais D, Lassonde M: Pilot case study of the therapeutic potential of hyperbaric oxygen therapy on chronic brain injury. J Neurol Sci. 2007, 253 (1-2): 94-105. 10.1016/j.jns.2006.12.005. Epub 2007 Jan 16CrossRefPubMed Hardy P, Johnston KM, De Beaumont L, Montgomery DL, Lecomte JM, Soucy JP, Bourbonnais D, Lassonde M: Pilot case study of the therapeutic potential of hyperbaric oxygen therapy on chronic brain injury. J Neurol Sci. 2007, 253 (1-2): 94-105. 10.1016/j.jns.2006.12.005. Epub 2007 Jan 16CrossRefPubMed
26.
go back to reference Shi XY, Tang ZQ, Sun D, He XJ: Evaluation of hyperbaric oxygen treatment of neuropsychiatric disorders following traumatic brain injury. Chin Med J (Engl). 2006, 119 (23): 1978-82. Shi XY, Tang ZQ, Sun D, He XJ: Evaluation of hyperbaric oxygen treatment of neuropsychiatric disorders following traumatic brain injury. Chin Med J (Engl). 2006, 119 (23): 1978-82.
27.
go back to reference Golden Z, Golden CJ, Neubauer RA: Improving neuropsychological function after chronic brain injury with hyperbaric oxygen. Disabil Rehabil. 2006, 28 (22): 1379-86. 10.1080/09638280600638364.CrossRefPubMed Golden Z, Golden CJ, Neubauer RA: Improving neuropsychological function after chronic brain injury with hyperbaric oxygen. Disabil Rehabil. 2006, 28 (22): 1379-86. 10.1080/09638280600638364.CrossRefPubMed
28.
go back to reference Collins MW, Lovell MR, Mckeag DB: Current Issues in managing sports-related concussion. JAMA. 1999, 282: 2283-2285. 10.1001/jama.282.24.2283.CrossRefPubMed Collins MW, Lovell MR, Mckeag DB: Current Issues in managing sports-related concussion. JAMA. 1999, 282: 2283-2285. 10.1001/jama.282.24.2283.CrossRefPubMed
29.
go back to reference Collins MW, Grindel SH, Lovell MR, Dede DE, Moser DJ, Phalin BR, Nogle S, Wasik M, Cordry D, Sears SF, Nicolette G, Indelicato P, McKeag D: Relationship between concussion and neuropsychological performance in college football players. JAMA. 1999, 282: 989-991. 10.1001/jama.282.10.989.CrossRef Collins MW, Grindel SH, Lovell MR, Dede DE, Moser DJ, Phalin BR, Nogle S, Wasik M, Cordry D, Sears SF, Nicolette G, Indelicato P, McKeag D: Relationship between concussion and neuropsychological performance in college football players. JAMA. 1999, 282: 989-991. 10.1001/jama.282.10.989.CrossRef
30.
go back to reference Iverson GL, Lovell MR, Collins MW: Interpreting change on ImPACT following sport concussion. Clin Neuropsychol. 2003, 17: 460-467.CrossRefPubMed Iverson GL, Lovell MR, Collins MW: Interpreting change on ImPACT following sport concussion. Clin Neuropsychol. 2003, 17: 460-467.CrossRefPubMed
Metadata
Title
Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports
Author
Kenneth P Stoller
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Medical Gas Research / Issue 1/2011
Electronic ISSN: 2045-9912
DOI
https://doi.org/10.1186/2045-9912-1-17

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