Published in:
01-02-2004 | Poster presentation
Hydroxyethyl starch but not crystalloid resuscitation improves impairment of intestinal microvascular perfusion during normotensive sepsis
Authors:
J Adolphs, T Schäfer, S Mousa, H Habazettl, M Schäfer, M Welte
Published in:
Critical Care
|
Special Issue 1/2004
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Excerpt
During sepsis the impairment of gut microvascular perfusion and activation of leukocytes lead to mucosal damage and aggravation of systemic inflammation. Recently, hydroxyethyl starch (HES) has been shown to attenuate deterioration of skin microcirculation in endotoxic hamsters [
1]. This study investigates the effects of fluid resuscitation with HES or isotonic saline solution (NaCl) on intestinal microvascular perfusion in a rat model of normotensive endotoxemia. …