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Keynote webinar | Spotlight on medication adherence

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Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
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AIDS Research and Therapy
Published in: AIDS Research and Therapy 1/2022

Open Access 01-12-2022 | Human Immunodeficiency Virus | Research

Impact of antiretroviral therapy (ART) duration on ART adherence among men who have sex with men (MSM) living with HIV in Jinan of China

Authors: Kedi Jiao, Meizhen Liao, Guangmei Liu, Yanmei Bi, Xiuhong Zhao, Qian Chen, Jing Ma, Yu Yan, Chunxiao Cheng, Yijun Li, Wenwen Jia, Lina Wang, Yanwen Cao, Zhonghui Zhao, Xuan Yang, Jing Meng, Jianzhuo Li, Xinrui Li, Chunmei Wang, Dianmin Kang, Wei Ma

Published in: AIDS Research and Therapy | Issue 1/2022

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Abstract

Background

Consistent and complete adherence is considered an essential requirement for patients on antiretroviral therapy (ART). This study aimed to evaluate the impact of ART duration on ART adherence, identify the trend of complete adherence, and compare the factors associated with ART adherence between short-term and long-term ART group among men who have sex with men (MSM) living with HIV in Jinan of China.

Methods

MSM living with HIV aged 18 or above and currently on ART were recruited from October to December 2020 using convenience sampling. Univariate and multivariable logistic regressions were used to evaluate the impact of ART duration on adherence and compare factors associated with ART adherence between subgroups. The Mann–Kendall test was used to identify the trend of complete adherence.

Results

A total of 585 participants were included in analysis, consisting of 352 on short-term ART (ART initiation ≤ 3 years) and 233 on long-term ART (ART initiation > 3 years). Significant difference of complete ART adherence between short-term and long-term ART group was detected (79.8% vs. 69.1%, P = 0.003). Multivariable analysis showed that men with longer ART duration were less likely to report complete ART adherence (AOR = 0.88, 95% CI 0.81–0.95). A descending trend of complete adherence was identified (Z = 1.787, P = 0.037). Alcohol use and lack of medication reminders were barriers to complete adherence for both of the subgroups.

Conclusions

Sustained efforts to encourage maintaining adherence for a lifetime are necessary, especially for those on long-term ART. Future interventions should be tailored to subgroups with different ART duration and individuals with specific characteristics.
Appendix
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Metadata
Title
Impact of antiretroviral therapy (ART) duration on ART adherence among men who have sex with men (MSM) living with HIV in Jinan of China
Authors
Kedi Jiao
Meizhen Liao
Guangmei Liu
Yanmei Bi
Xiuhong Zhao
Qian Chen
Jing Ma
Yu Yan
Chunxiao Cheng
Yijun Li
Wenwen Jia
Lina Wang
Yanwen Cao
Zhonghui Zhao
Xuan Yang
Jing Meng
Jianzhuo Li
Xinrui Li
Chunmei Wang
Dianmin Kang
Wei Ma
Publication date
01-12-2022
Publisher
BioMed Central
Published in
AIDS Research and Therapy / Issue 1/2022
Electronic ISSN: 1742-6405
DOI
https://doi.org/10.1186/s12981-022-00482-z

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Keynote webinar | Spotlight on medication adherence

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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