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Journal of Clinical Immunology

Published in:

01-03-2009

Human Immune Memory to Yellow Fever and Smallpox Vaccination

Authors: Jens Wrammert, Joe Miller, Rama Akondy, Rafi Ahmed

Published in: Journal of Clinical Immunology | Issue 2/2009

Abstract

Background

Establishment of immunological memory is a hallmark of adaptive immune responses and the biological mechanism for the success of vaccines. However, in humans, much of our knowledge about adaptive immune responses derives from studies of chronic viral infections.

Objective

Here, we summarize the work of our laboratory and others on B and T cell responses and the establishment and maintenance of immune memory after acute viral infections induced by vaccination with two of the most successful vaccines to date, the yellow fever and the smallpox vaccines.

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Title: Human Immune Memory to Yellow Fever and Smallpox Vaccination
Authors: Jens Wrammert
Joe Miller
Rama Akondy
Rafi Ahmed
Publication date: 01-03-2009
Publisher: Springer US
Published in: Journal of Clinical Immunology / Issue 2/2009
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI: https://doi.org/10.1007/s10875-008-9267-3

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Abstract

Background

Objective

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