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Published in: Archives of Virology 10/2008

01-10-2008 | Brief Report

Human group A rotavirus P[8] Hun9-like and rare OP354-like strains are circulating among diarrhoeic children in Eastern India

Authors: S. Samajdar, S. Ghosh, D. Dutta, M. Chawla-Sarkar, N. Kobayashi, T. N. Naik

Published in: Archives of Virology | Issue 10/2008

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Abstract

During 2004–2006, group A rotavirus P[8] strains were the major VP4 genotype (43.2%, = 317) among diarrhoeic children in Eastern India. Phylogenetic analysis of VP8* amino acid sequences of 16 of these strains with other P[8] strains revealed four distinct lineages. P[8] strains from Eastern India clustered within rare OP354-like and Hun9-like lineages, pointing towards co-prevalence of divergent P[8] strains. Although it is unclear whether the observed genetic diversity might affect to some extent the efficacy of vaccines, the present study emphasized further efforts to address the much lacking information on diversity of P[8] strains across the Indian subcontinent.
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Metadata
Title
Human group A rotavirus P[8] Hun9-like and rare OP354-like strains are circulating among diarrhoeic children in Eastern India
Authors
S. Samajdar
S. Ghosh
D. Dutta
M. Chawla-Sarkar
N. Kobayashi
T. N. Naik
Publication date
01-10-2008
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 10/2008
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-008-0187-6

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