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Published in: Journal of General Internal Medicine 8/2009

01-08-2009 | Health Policy

How Well Do Guidelines Incorporate Evidence on Patient Preferences?

Authors: Christopher AKY Chong, MD, Ing-je Chen, BSc, Gary Naglie, MD, Murray D. Krahn, MD,MSc

Published in: Journal of General Internal Medicine | Issue 8/2009

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ABSTRACT

BACKGROUND

Clinical practice guidelines (CPG) are meant to consider important values such as patient preferences.

OBJECTIVE

To assess how well clinical practice guidelines (CPGs) integrate evidence on patient preferences compared with that on treatment effectiveness.

DESIGN

A cross-sectional review of a listing in 2006 of CPGs judged to be the best in their fields by an external joint government and medical association body.

STUDY SELECTION

Exclusion criterion was unavailability in electronic format. Sixty-five of 71 listed CPGs met selection criteria.

MEASUREMENTS

Two instruments originally constructed to evaluate the overall quality of CPGs were adapted to specifically assess the quality of integrating information on patient preference vs. treatment effectiveness. Counts of words and references in each CPG associated with patient preferences vs. treatment effectiveness were performed. Two reviewers independently assessed each CPG.

MAIN RESULTS

Based on our adapted instruments, CPGs scored significantly higher (p < 0.001) on the quality of integrating treatment effectiveness compared with patient preferences evidence (mean instrument one scores on a scale of 0.25 to 1.00: 0.65 vs. 0.43; mean instrument two scores on a scale of 0 to 1: 0.58 vs. 0.18). The average percentage of the total word count dedicated to treatment effectiveness was 24.2% compared with 4.6% for patient preferences. The average percentage of references citing treatment effectiveness evidence was 36.6% compared with 6.0% for patient preferences.

CONCLUSION

High quality CPGs poorly integrate evidence on patient preferences. Barriers to incorporating preference evidence into CPGs should be addressed.
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Literature
1.
go back to reference Singer DE, Albers GW, Dalen JE, Go AS, Halperin JL, Manning WJ. Antithrombotic therapy in atrial fibrillation: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126:429S–456S.PubMedCrossRef Singer DE, Albers GW, Dalen JE, Go AS, Halperin JL, Manning WJ. Antithrombotic therapy in atrial fibrillation: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126:429S–456S.PubMedCrossRef
2.
go back to reference Holoweiko M. What cookbook medicine will mean for you. Med Econ. 1989; 66: 118–20, 125–117, 130–113.PubMed Holoweiko M. What cookbook medicine will mean for you. Med Econ. 1989; 66: 118–20, 125–117, 130–113.PubMed
3.
go back to reference Sackett D, Strauss S, Richardson W, Rosenberg W, Haynes R. Evidence-based medicine: how to practice and teach EBM. 2nd ed. London: Churchill Livingstone; 2000. Sackett D, Strauss S, Richardson W, Rosenberg W, Haynes R. Evidence-based medicine: how to practice and teach EBM. 2nd ed. London: Churchill Livingstone; 2000.
4.
go back to reference Hayward RS, Wilson MC, Tunis SR, Bass EB, Guyatt G. Users’ guides to the medical literature. VIII. How to use clinical practice guidelines. A. Are the recommendations valid? The Evidence-Based Medicine Working Group. JAMA. 1995;274:570–4.PubMedCrossRef Hayward RS, Wilson MC, Tunis SR, Bass EB, Guyatt G. Users’ guides to the medical literature. VIII. How to use clinical practice guidelines. A. Are the recommendations valid? The Evidence-Based Medicine Working Group. JAMA. 1995;274:570–4.PubMedCrossRef
5.
go back to reference Gafni A, Charles C, Whelan T. The physician-patient encounter: the physician as a perfect agent for the patient versus the informed treatment decision-making model. Soc Sci Med. 1998;47:347–54.PubMedCrossRef Gafni A, Charles C, Whelan T. The physician-patient encounter: the physician as a perfect agent for the patient versus the informed treatment decision-making model. Soc Sci Med. 1998;47:347–54.PubMedCrossRef
6.
go back to reference Ristvedt SL, McFarland EG, Weinstock LB, Thyssen EP. Patient preferences for CT colonography, conventional colonoscopy and bowel preparation. Am J Gastroenterol. 2003;98:578–85.PubMedCrossRef Ristvedt SL, McFarland EG, Weinstock LB, Thyssen EP. Patient preferences for CT colonography, conventional colonoscopy and bowel preparation. Am J Gastroenterol. 2003;98:578–85.PubMedCrossRef
7.
go back to reference Ross CK, Steward CA, Sinacore JM. The importance of patient preferences in the measurement of health care satisfaction. Medical Care. 1993;31:1138–49.PubMedCrossRef Ross CK, Steward CA, Sinacore JM. The importance of patient preferences in the measurement of health care satisfaction. Medical Care. 1993;31:1138–49.PubMedCrossRef
8.
go back to reference Gold MR, Siegel JE, Russell LB, Weinstein MC, eds. Cost-Effectiveness in Health and Medicine. New York: Oxford University Press; 1996. Gold MR, Siegel JE, Russell LB, Weinstein MC, eds. Cost-Effectiveness in Health and Medicine. New York: Oxford University Press; 1996.
9.
go back to reference Gage BF, Cardinalli AB, Owens DK. The effect of stroke and stroke prophylaxis with aspirin or warfarin on quality of life. Arch Intern Med. 1996;156:1829–36.PubMedCrossRef Gage BF, Cardinalli AB, Owens DK. The effect of stroke and stroke prophylaxis with aspirin or warfarin on quality of life. Arch Intern Med. 1996;156:1829–36.PubMedCrossRef
10.
go back to reference Sox H, Marton K, Blatt M, Higgins M. Medical Decision MakingLondon: RSM Press; 2006. Sox H, Marton K, Blatt M, Higgins M. Medical Decision MakingLondon: RSM Press; 2006.
11.
go back to reference Samsa GP, Matchar DB, Goldstein L, et al. Utilities for major stroke: results from a survey of preferences among persons at increased risk for stroke. Am Heart J. 136(4 Pt 1):703–713. Samsa GP, Matchar DB, Goldstein L, et al. Utilities for major stroke: results from a survey of preferences among persons at increased risk for stroke. Am Heart J. 136(4 Pt 1):703–713.
12.
go back to reference Bajorek BV, Ogle SJ, Duguid MJ, Shenfield GM, Krass I. Management of warfarin in atrial fibrillation: views of health professionals, older patients and their carers. Med J Aust. 2007;186:175–80.PubMed Bajorek BV, Ogle SJ, Duguid MJ, Shenfield GM, Krass I. Management of warfarin in atrial fibrillation: views of health professionals, older patients and their carers. Med J Aust. 2007;186:175–80.PubMed
13.
go back to reference Fuller R, Dudley N, Blacktop J. Avoidance hierarchies and preferences for anticoagulation—semi-qualitative analysis of older patients’ views about stroke prevention and the use of warfarin. Age Ageing. 2004;33:608–11.PubMedCrossRef Fuller R, Dudley N, Blacktop J. Avoidance hierarchies and preferences for anticoagulation—semi-qualitative analysis of older patients’ views about stroke prevention and the use of warfarin. Age Ageing. 2004;33:608–11.PubMedCrossRef
14.
go back to reference Man-Son-Hing M, Laupacis A, O’Connor AM, et al. A patient decision aid regarding antithrombotic therapy for stroke prevention in atrial fibrillation: a randomized controlled trial. JAMA. 1999;282:737–43.PubMedCrossRef Man-Son-Hing M, Laupacis A, O’Connor AM, et al. A patient decision aid regarding antithrombotic therapy for stroke prevention in atrial fibrillation: a randomized controlled trial. JAMA. 1999;282:737–43.PubMedCrossRef
15.
go back to reference Man-Son-Hing M, O’Connor AM, Drake E, Biggs J, Hum V, Laupacis A. The effect of qualitative vs. quantitative presentation of probability estimates on patient decision-making: a randomized trial. Health Expect. 5:246–255 Man-Son-Hing M, O’Connor AM, Drake E, Biggs J, Hum V, Laupacis A. The effect of qualitative vs. quantitative presentation of probability estimates on patient decision-making: a randomized trial. Health Expect. 5:246–255
16.
go back to reference Coulter A. Paternalism or partnership? Patients have grown up—and there’s no going back. BMJ. 1999;319:719–20.PubMed Coulter A. Paternalism or partnership? Patients have grown up—and there’s no going back. BMJ. 1999;319:719–20.PubMed
17.
go back to reference Barry MJ. Involving patients in medical decisions, how can physicians do better? JAMA. 1999;282:2356–7.PubMedCrossRef Barry MJ. Involving patients in medical decisions, how can physicians do better? JAMA. 1999;282:2356–7.PubMedCrossRef
18.
go back to reference Bensing J. Bridging the gap. The separate worlds of evidence-based medicine and patient-centered medicine. Patient Educ Couns. 2000;39:17–25.PubMedCrossRef Bensing J. Bridging the gap. The separate worlds of evidence-based medicine and patient-centered medicine. Patient Educ Couns. 2000;39:17–25.PubMedCrossRef
19.
go back to reference Schunemann HJ, Fretheim A, Oxman AD. Improving the use of research evidence in guideline development: 10. Integrating values and consumer involvement. Health Res Policy Syst. 2006;4: 22.PubMedCrossRef Schunemann HJ, Fretheim A, Oxman AD. Improving the use of research evidence in guideline development: 10. Integrating values and consumer involvement. Health Res Policy Syst. 2006;4: 22.PubMedCrossRef
20.
go back to reference Owens DK. Spine update. Patient preferences and the development of practice guidelines. Spine. 1998;23:1073–9.PubMedCrossRef Owens DK. Spine update. Patient preferences and the development of practice guidelines. Spine. 1998;23:1073–9.PubMedCrossRef
21.
go back to reference Cabana MD, Rand CS, Powe NR, et al. Why don’t physicians follow clinical practice guidelines. JAMA. 1999;282:1458–65.PubMedCrossRef Cabana MD, Rand CS, Powe NR, et al. Why don’t physicians follow clinical practice guidelines. JAMA. 1999;282:1458–65.PubMedCrossRef
23.
go back to reference Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Qual Saf Health Care. 2003;12:18–23. Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Qual Saf Health Care. 2003;12:18–23.
25.
go back to reference Shaneyfelt TM, Mayo-Smith MF, Rothwangl J. Are guidelines following guidelines? The methodological quality of clinical practice guidelines in the peer-reviewed medical literature. JAMA. 1999;281:1900–5.PubMedCrossRef Shaneyfelt TM, Mayo-Smith MF, Rothwangl J. Are guidelines following guidelines? The methodological quality of clinical practice guidelines in the peer-reviewed medical literature. JAMA. 1999;281:1900–5.PubMedCrossRef
26.
go back to reference Canadian Health Services Research Foundation. Weighing up the evidence: Making evidence-informed guidance accurate, achievable and acceptable. Ottawa (ON): Canadian Health Services Research Foundation; 2006. Canadian Health Services Research Foundation. Weighing up the evidence: Making evidence-informed guidance accurate, achievable and acceptable. Ottawa (ON): Canadian Health Services Research Foundation; 2006.
27.
go back to reference Schattner A, Fletcher RH. Research evidence and the individual patient. Q J Med. 2003;96:1–5. Schattner A, Fletcher RH. Research evidence and the individual patient. Q J Med. 2003;96:1–5.
28.
go back to reference Marks DF, Murray M, Evans B, Willig C, Woodall C, Sykes CM. Health psychology: theory, research and practice. 2nd ed. Thousand Oaks, CA: Sage; 2005. Marks DF, Murray M, Evans B, Willig C, Woodall C, Sykes CM. Health psychology: theory, research and practice. 2nd ed. Thousand Oaks, CA: Sage; 2005.
29.
go back to reference Green J, Britten N. Qualitative research and evidence based medicine. BMJ. 1998;316:1230–2.PubMed Green J, Britten N. Qualitative research and evidence based medicine. BMJ. 1998;316:1230–2.PubMed
30.
go back to reference Ryan M, Farrar S. Using conjoint analysis to elicit preference for health care. BMJ. 2000;320:1530–3.PubMedCrossRef Ryan M, Farrar S. Using conjoint analysis to elicit preference for health care. BMJ. 2000;320:1530–3.PubMedCrossRef
31.
go back to reference Zimmer L. Qualitative meta-synthesis: a question of dialoguing with texts. J Adv Nurs. 2006;53:311–8.PubMedCrossRef Zimmer L. Qualitative meta-synthesis: a question of dialoguing with texts. J Adv Nurs. 2006;53:311–8.PubMedCrossRef
32.
go back to reference Feldman RD, Zou GY, Vandervoort MK, Wong CJ, Nelson SA, Feagan BG. A simplified approach to the treatment of uncomplicated hypertension. A cluster randomized, controlled trial. Hypertension. 2009 Feb 23 [epub ahead of print]. Feldman RD, Zou GY, Vandervoort MK, Wong CJ, Nelson SA, Feagan BG. A simplified approach to the treatment of uncomplicated hypertension. A cluster randomized, controlled trial. Hypertension. 2009 Feb 23 [epub ahead of print].
33.
go back to reference Cantor SB, Spann SJ, Volk RJ, Cardenas MP, Warren MM. Prostate cancer screening: a decision analysis. J Fam Pract. 1995;41:33–41.PubMed Cantor SB, Spann SJ, Volk RJ, Cardenas MP, Warren MM. Prostate cancer screening: a decision analysis. J Fam Pract. 1995;41:33–41.PubMed
34.
go back to reference Krahn MD, Mahoney JE, Eckman MH, Trachtenberg J, Pauker SG, Detsky AS. Screening for prostate cancer. A decision analytic view. JAMA. 1994;272:773–80.PubMedCrossRef Krahn MD, Mahoney JE, Eckman MH, Trachtenberg J, Pauker SG, Detsky AS. Screening for prostate cancer. A decision analytic view. JAMA. 1994;272:773–80.PubMedCrossRef
35.
go back to reference Frosch DL, Bhatnagar V, Tally S, Hamori CJ, Kaplan RM. A randomized controlled trial comparing alternative approaches for men considering prostate cancer screening. Arch Intern Med. 2008;168:363–9.PubMedCrossRef Frosch DL, Bhatnagar V, Tally S, Hamori CJ, Kaplan RM. A randomized controlled trial comparing alternative approaches for men considering prostate cancer screening. Arch Intern Med. 2008;168:363–9.PubMedCrossRef
Metadata
Title
How Well Do Guidelines Incorporate Evidence on Patient Preferences?
Authors
Christopher AKY Chong, MD
Ing-je Chen, BSc
Gary Naglie, MD
Murray D. Krahn, MD,MSc
Publication date
01-08-2009
Publisher
Springer-Verlag
Published in
Journal of General Internal Medicine / Issue 8/2009
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-009-0987-8

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