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Medical Oncology
Published in: Medical Oncology 1/2014

Open Access 01-01-2014 | Original Paper

Hodgkin lymphoma transformation of chronic lymphocytic leukemia: cases report and discussion

Authors: Maciej Kaźmierczak, Renata Kroll-Balcerzak, Andrzej Balcerzak, Elżbieta Czechowska, Lidia Gil, Krzysztof Sawiński, Andrzej Szczepaniak, Mieczysław Komarnicki

Published in: Medical Oncology | Issue 1/2014

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Abstract

B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is the most common form of leukemia affecting adults in Europe and North America. Large B-cell lymphoma known as Richter’s syndrome (RS) may develop approximately in 3–15 % patients. Furthermore, other hematological malignancies may also occur as RS variants, among them—Hodgkin lymphoma (HL). CLL/SLL transformation into HL is observed in about 0.5 % of patients, and till now, fewer than 100 cases have been reported in the medical literature. We present two cases of HL transformation of CLL/SLL and review the previously published literature.
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Metadata
Title
Hodgkin lymphoma transformation of chronic lymphocytic leukemia: cases report and discussion
Authors
Maciej Kaźmierczak
Renata Kroll-Balcerzak
Andrzej Balcerzak
Elżbieta Czechowska
Lidia Gil
Krzysztof Sawiński
Andrzej Szczepaniak
Mieczysław Komarnicki
Publication date
01-01-2014
Publisher
Springer US
Published in
Medical Oncology / Issue 1/2014
Print ISSN: 1357-0560
Electronic ISSN: 1559-131X
DOI
https://doi.org/10.1007/s12032-013-0800-8

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