Published in:
01-12-2011 | VASCULITIS (LUIS R. ESPINOZA, SECTION EDITOR)
HIV Infection and Clinical Spectrum of Associated Vasculitides
Authors:
Nirupa Patel, Neema Patel, Tahir Khan, Neej Patel, Luis R. Espinoza
Published in:
Current Rheumatology Reports
|
Issue 6/2011
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Abstract
Various infections have been causative in the pathogenesis of systemic vasculitides, and HIV infection is not spared. In an immunocompromised host, cytomegalovirus, Epstein-Barr virus, varicella zoster virus, herpes simplex virus, hepatitis B and hepatitis C virus, and mycobacteria, along with HIV infection can cause vasculitis. Herein we emphasize the spectrum of vasculitides, their pathogenesis, presentation, course, and therapy in the HIV-infected population. Every spectrum and size of the blood vessel involvement have been seen in HIV-associated vasculitides. We review each spectrum in detail and describe our experience with polyarteritis nodosa, the most common presentation occurring in HIV-infected patients. We also discuss the differences in HIV, hepatitis B, and hepatitis C- related polyarteritis nodosa in detail.