Published in:
01-03-2017 | Correspondence
High-Resolution Vessel Wall MRI
Appearance of Intravascular Lymphoma Mimics Central Nervous System Vasculitis
Authors:
Joanna D Schaafsma, Ferdinand Hui, Dolora Wisco, Susan M Staugaitis, Ken Uchino, Elizabeth Kouzmitcheva, Cheryl Jaigobin, Lili-Naz Hazrati, David J Mikulis, Daniel M Mandell
Published in:
Clinical Neuroradiology
|
Issue 1/2017
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Excerpt
Intravascular lymphoma is a subtype of diffuse large B‑cell lymphoma characterized by neoplastic proliferation within the vascular lumen. It is a mimic of central nervous system (CNS) vasculitis: both diseases often present with recurrent focal neurological deficits and/or cognitive decline, routine brain imaging typically shows ischemic strokes of varying ages, angiography demonstrates multifocal narrowing of intracranial arteries and cerebrospinal fluid (CSF) analysis demonstrates a mildly elevated leukocyte count and/or elevated protein concentration [
1‐
3]. Differentiation between intravascular lymphoma and CNS vasculitis is important as their treatment differs; however, the diagnosis of intravascular lymphoma is commonly delayed or missed as it requires tissue biopsy [
1]. …