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Published in: Annals of Hematology 3/2018

01-03-2018 | Original Article

High prevalence of hepatitis B virus infection in patients with aggressive B cell non-Hodgkin’s lymphoma in China

Authors: Chaoyu Wang, Bing Xia, Qiaoyang Ning, Haifeng Zhao, Hongliang Yang, Zhigang Zhao, Xiaofang Wang, Yafei Wang, Yong Yu, Yizhuo Zhang

Published in: Annals of Hematology | Issue 3/2018

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Abstract

We retrospectively analyzed a large study to investigate the association of hepatitis B virus (HBV) with aggressive B cell non-Hodgkin’s lymphoma (aggressive B-NHL) in China, where HBV is endemic. HBV was present in 39 aggressive B-NHL patients (10.46%), 13 indolent B-NHL patients (5.09%), 12 multiple myeloma (MM) patients (3.67%), and 5 solitary plasmacytoma (SP) patients (6.67%). HBV infection was significantly associated with increased risks for aggressive B-NHL (P < 0.01). HBV seems to have a very important role in the pathogenesis of aggressive B-NHL in China.
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Metadata
Title
High prevalence of hepatitis B virus infection in patients with aggressive B cell non-Hodgkin’s lymphoma in China
Authors
Chaoyu Wang
Bing Xia
Qiaoyang Ning
Haifeng Zhao
Hongliang Yang
Zhigang Zhao
Xiaofang Wang
Yafei Wang
Yong Yu
Yizhuo Zhang
Publication date
01-03-2018
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 3/2018
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-017-3188-2

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