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Published in: Journal of Gastrointestinal Cancer 1/2021

01-03-2021 | Hepatocellular Carcinoma | Case Report

Large Multifocal Hepatocarcinoma: Technical Details of Treatment with Combined Transarterial Chemoembolization, Microwave and Radiofrequency Ablation

Authors: Enrico Boninsegna, Emilio Simonini, Stefano Crosara, Michela De Angelis, Luigi Boccia, Stefano Colopi

Published in: Journal of Gastrointestinal Cancer | Issue 1/2021

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Excerpt

Percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) for the treatment of hepatocellular carcinoma (HCC) have shown excellent therapeutic efficacies, often comparable with those of surgical resection [13]. Combined transarterial chemoembolization (TACE) and percutaneous ablations (RFA/MWA) were first introduced as strategies to obtain a larger treatment zone during ablation procedures [4]. The efficacy of a combined approach has been proven for small- and medium-sized HCCs [1, 57]; in addition, TACE-RFA/MWA can be applied for the treatment of small HCCs inconspicuous on ultrasound (US) or unenhanced computed tomography (CT), two guiding modalities for minimally invasive ablation procedures [2, 8]. The efficacy of combined TACE and percutaneous technologies for large hepatocellular carcinoma in patients not suitable for surgical resection has not yet been proven [9]. We report two cases of a giant multifocal hepatocarcinoma, successfully treated with combined TACE-MWA and TACE-RFA. …
Literature
6.
go back to reference Morimoto M, Numata K, Kondou M, Nozaki A, Morita S, Tanaka K. Midterm outcomes in patients with intermediate-sized hepatocellular carcinoma: a randomized controlled trial for determining the efficacy of radiofrequency ablation combined with transcatheter arterial chemoembolization. Cancer. 2010;116(23):5452–60. https://doi.org/10.1002/cncr.25314.CrossRefPubMed Morimoto M, Numata K, Kondou M, Nozaki A, Morita S, Tanaka K. Midterm outcomes in patients with intermediate-sized hepatocellular carcinoma: a randomized controlled trial for determining the efficacy of radiofrequency ablation combined with transcatheter arterial chemoembolization. Cancer. 2010;116(23):5452–60. https://​doi.​org/​10.​1002/​cncr.​25314.CrossRefPubMed
9.
go back to reference Liu Z, Gao F, Yang G, Singh S, Lu M, Zhang T, et al. Combination of radiofrequency ablation with transarterial chemoembolization for hepatocellular carcinoma: an up-to-date meta-analysis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014;35(8):7407–13. https://doi.org/10.1007/s13277-014-1976-z.CrossRef Liu Z, Gao F, Yang G, Singh S, Lu M, Zhang T, et al. Combination of radiofrequency ablation with transarterial chemoembolization for hepatocellular carcinoma: an up-to-date meta-analysis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014;35(8):7407–13. https://​doi.​org/​10.​1007/​s13277-014-1976-z.CrossRef
Metadata
Title
Large Multifocal Hepatocarcinoma: Technical Details of Treatment with Combined Transarterial Chemoembolization, Microwave and Radiofrequency Ablation
Authors
Enrico Boninsegna
Emilio Simonini
Stefano Crosara
Michela De Angelis
Luigi Boccia
Stefano Colopi
Publication date
01-03-2021
Publisher
Springer US
Published in
Journal of Gastrointestinal Cancer / Issue 1/2021
Print ISSN: 1941-6628
Electronic ISSN: 1941-6636
DOI
https://doi.org/10.1007/s12029-020-00416-w

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