Published in:
01-03-2021 | Hepatocellular Carcinoma | Case Report
Large Multifocal Hepatocarcinoma: Technical Details of Treatment with Combined Transarterial Chemoembolization, Microwave and Radiofrequency Ablation
Authors:
Enrico Boninsegna, Emilio Simonini, Stefano Crosara, Michela De Angelis, Luigi Boccia, Stefano Colopi
Published in:
Journal of Gastrointestinal Cancer
|
Issue 1/2021
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Excerpt
Percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) for the treatment of hepatocellular carcinoma (HCC) have shown excellent therapeutic efficacies, often comparable with those of surgical resection [
1‐
3]. Combined transarterial chemoembolization (TACE) and percutaneous ablations (RFA/MWA) were first introduced as strategies to obtain a larger treatment zone during ablation procedures [
4]. The efficacy of a combined approach has been proven for small- and medium-sized HCCs [
1,
5‐
7]; in addition, TACE-RFA/MWA can be applied for the treatment of small HCCs inconspicuous on ultrasound (US) or unenhanced computed tomography (CT), two guiding modalities for minimally invasive ablation procedures [
2,
8]. The efficacy of combined TACE and percutaneous technologies for large hepatocellular carcinoma in patients not suitable for surgical resection has not yet been proven [
9]. We report two cases of a giant multifocal hepatocarcinoma, successfully treated with combined TACE-MWA and TACE-RFA. …