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Abdominal Radiology
Published in: Abdominal Radiology 3/2013

01-06-2013

Hepatic adenomatosis: spectrum of imaging findings

Authors: Siva P. Raman, Ralph H. Hruban, Elliot K. Fishman

Published in: Abdominal Radiology | Issue 3/2013

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Abstract

Objective

This pictorial essay reviews the imaging appearance and differential diagnosis of hepatic adenomatosis.

Conclusion

In addition to such entities as multifocal hepatocellular carcinoma, metastases, and multiple focal nodular hyperplasia, hepatic adenomatosis should also be considered when confronted with multiple hypervascular liver lesions. Certain CT and MRI features can strongly suggest the diagnosis of adenomatosis.
Literature
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Grazioli L, Federle MP, Brancatelli G, et al. (2001) Hepatic adenomas: imaging and pathologic findings. Radiographics 21:877–894PubMed
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Brancatelli G, Federle MP, Vullierme M, et al. (2006) CT and MR imaging evaluation of hepatic adenoma. J Comput Assit Tomogr 30(5):745–750CrossRef
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Grazioli L, Federle MP, Ichikawa T, et al. (2000) Liver adenomatosis: clinical, histopathological, and imaging findings in 15 patients. Radiology 216:395–402PubMed
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Ulu EMK, Uyusur A, Ekici Y, et al. (2009) Mutlidetector CT findings of spontaneous rupture of hepatic adenoma in a patient with hepatic adenomatosis. Diagn Interv Radiol 15:135–138PubMed
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Bluteau O, Jeannot E, Bioulac-Sage P, et al. (2002) Bi-allelic inactivation of TCF1 in hepatic adenomas. Nat Genet 32(2):312–315PubMedCrossRef
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Lim AKP, Patel N, Gedroyc WMW, Blomley MJK, et al. (2002) Hepatocellular adenoma: diagnostic difficulties and novel imaging techniques. Br J Radiol 75:695–699PubMed
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Greaves WOC, Battacharya B (2008) Hepatic adenomatosis. Arch Pathol Lab Med 132:1951–1955PubMed
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Volmar KE, Burchette JL, Creager AJ (2003) Hepatic adenomatosis in glycogen storage disease type Ia: Report of an unusual case with unusual histology. Arch Pathol Lab Med 127:e402–e405PubMed
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Furlan A, van der Windt DJ, Nalesnik MA, et al. (2008) Multiple hepatic adenomas associated with liver steatosis at CT and MRI: a case control study. AJR Am J Roentgenol 191:1430–1435PubMedCrossRef
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Di Sandro S, Slim AO, Lauterio A, et al. (2009) Liver adenomatosis: a rare indication for living donor liver transplantation. Transpl Proc 41:1375–1377CrossRef
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Ichikawa T, Federle MP, Grazioli L, Nalesnik M (2000) Hepatocellular adenoma: multiphasic CT and histopathology findings in 25 patients. Radiology 214:861–868PubMed
Metadata
Title
Hepatic adenomatosis: spectrum of imaging findings
Authors
Siva P. Raman
Ralph H. Hruban
Elliot K. Fishman
Publication date
01-06-2013
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 3/2013
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-012-9906-2

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