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Published in:

01-10-2006

Hepatectomy for Colorectal Liver Metastases with Macroscopic Intrabiliary Tumor Growth

Authors: Teiichi Sugiura, MD, Masato Nagino, MD, Koji Oda, MD, Tomoki Ebata, MD, Hideki Nishio, MD, Toshiyuki Arai, MD, Yuji Nimura, MD

Published in: World Journal of Surgery | Issue 10/2006

Abstract

Objectives

We set out to clarify the clinicopathologic characteristics of colorectal liver metastases with macroscopic intrabiliary tumor growth and to determine optimal surgical management.

Methods

Over 15 years, 6 of 103 patients undergoing hepatectomy for colorectal liver metastases had macroscopic intrabiliary tumor growth and were analyzed retrospectively.

Results

We performed 11 operations for the 6 patients, consisting of 10 hepatectomies (including 1 hepatopancreatoduodenectomy) and 1 pancreatoduodenectomy. Three patients survived more than 5 years: 1 died of pulmonary emphysema with no sign of recurrence 101 months after initial hepatectomy; the 2 others were alive with no sign of recurrence at 74 and 145 months after initial hepatectomy. Median survival time of all 6 patients was 87.5 months. Histologically, intrabiliary tumor growth had two components: intraluminal and intraepithelial extension. In the proximal direction, distance between these two components ranged from 4–10 mm.

Conclusion

Aggressive surgical treatment can improve chances of long-term survival for patients with macroscopic intrabiliary growth of colorectal liver metastasis. Although nonanatomic limited resection is a common procedure for colorectal liver metastasis, anatomic hepatobiliary resection is recommended.

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Title: Hepatectomy for Colorectal Liver Metastases with Macroscopic Intrabiliary Tumor Growth
Authors: Teiichi Sugiura, MD
Masato Nagino, MD
Koji Oda, MD
Tomoki Ebata, MD
Hideki Nishio, MD
Toshiyuki Arai, MD
Yuji Nimura, MD
Publication date: 01-10-2006
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 10/2006
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-006-0205-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Hepatectomy for Colorectal Liver Metastases with Macroscopic Intrabiliary Tumor Growth

Abstract

Objectives

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

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